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pro vyhledávání: '"Xiang Y. Tan"'
Autor:
Richard P. Junghans, Scot A. Marsters, Dezhen Zhang, Avi Ashkenazi, Randal A. Byrn, Steven M. Chamow, Shilpa M. Mhatre, Xiang Y. Tan, David H. Peers
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 153(9)
We have developed a humanized, bispecific immunoadhesin-antibody (BsIAb) that targets and kills HIV-infected cells. Comprised of CD4-IgG and humanized anti-CD3-IgG, this BsIAb is bifunctional. First, in targeting, it exploits the natural affinity of