Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Xiang S. Ye"'
Publikováno v:
Chinese Journal of Cancer, Vol 35, Iss 1, Pp 1-7 (2016)
Abstract Gastric cancer (GC) is a highly heterogenic disease, and it is the second leading cause of cancer death in the world. Common chemotherapies are not very effective for GC, which often presents as an advanced or metastatic disease at diagnosis
Externí odkaz:
https://doaj.org/article/5b6f5600d1a44292924f7285179eb040
Autor:
Nikhil Wagle, Sean G. Buchanan, Nancy U. Lin, Sara M. Tolaney, Eric P. Winer, Levi A. Garraway, Jill D. Kremer, Melissa E. Hughes, Gerald Batist, Quincy S. Chu, Gerard J. Oakley, Patricia S. Smith, John R. Stille, Valerie M. Jansen, Chunping Yu, Xiang S. Ye, Lacey M. Litchfield, Ricardo Martinez, Stephen H. Parsons, Adrienne G. Waks, Utthara Nayar, Kailey J. Kowalski, Karla Helvie, Pingping Mao, Flora Luo, Dewey Kim, Maxwell R. Lloyd, Jorge E. Buendia-Buendia, Gabriela N. Johnson, Xueqian Gong, Ofir Cohen, Seth A. Wander
Figure S9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f4429c0b5f6674a0a879dccdfd024b9
https://doi.org/10.1158/2159-8290.22535354.v1
https://doi.org/10.1158/2159-8290.22535354.v1
Autor:
Nikhil Wagle, Sean G. Buchanan, Nancy U. Lin, Sara M. Tolaney, Eric P. Winer, Levi A. Garraway, Jill D. Kremer, Melissa E. Hughes, Gerald Batist, Quincy S. Chu, Gerard J. Oakley, Patricia S. Smith, John R. Stille, Valerie M. Jansen, Chunping Yu, Xiang S. Ye, Lacey M. Litchfield, Ricardo Martinez, Stephen H. Parsons, Adrienne G. Waks, Utthara Nayar, Kailey J. Kowalski, Karla Helvie, Pingping Mao, Flora Luo, Dewey Kim, Maxwell R. Lloyd, Jorge E. Buendia-Buendia, Gabriela N. Johnson, Xueqian Gong, Ofir Cohen, Seth A. Wander
Mechanisms driving resistance to cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) in hormone receptor–positive (HR+) breast cancer have not been clearly defined. Whole-exome sequencing of 59 tumors with CDK4/6i exposure revealed multiple candidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89133c0f6a6b34907466acc61efd6697
https://doi.org/10.1158/2159-8290.c.6547832.v1
https://doi.org/10.1158/2159-8290.c.6547832.v1
Autor:
Sean G. Buchanan, James R. Henry, Robert M. Campbell, Christoph Reinhard, Gregory D. Plowman, David A. Barda, Xiang S. Ye, Hui-Rong Qian, Shaoyou Chu, Thompson Doman, Matthew Z. Dieter, Yu-Hua Hui, Scott W. Eastman, María José Lallena, Carmen Baquero, Carlos Marugán, Michele Dowless, Stephen R. Wasserman, Kenneth Weichert, Anna Pustilnik, Danalyn Manglicmot, Karen Froning, Ann M. Mc Nulty, Stephen Antonysamy, Avnish Kapoor, Li Fan, Chris Ficklin, Huimin Bian, Sufang Yao, Shaoling Jin, Bomie Han, Wayne Blosser, Xi Lin, Robert D. Van Horn, Li-Chun Chio, Philip W. Iversen, Yue Webster, Farhana F. Merzoug, Stephen H. Parsons, Jian Du, Xueqian Gong
LY3295668 chemical characterization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459c3119cab021ba3189b2c2e7d96d2e
https://doi.org/10.1158/2159-8290.22533034.v1
https://doi.org/10.1158/2159-8290.22533034.v1
Autor:
Nikhil Wagle, Sean G. Buchanan, Nancy U. Lin, Sara M. Tolaney, Eric P. Winer, Levi A. Garraway, Jill D. Kremer, Melissa E. Hughes, Gerald Batist, Quincy S. Chu, Gerard J. Oakley, Patricia S. Smith, John R. Stille, Valerie M. Jansen, Chunping Yu, Xiang S. Ye, Lacey M. Litchfield, Ricardo Martinez, Stephen H. Parsons, Adrienne G. Waks, Utthara Nayar, Kailey J. Kowalski, Karla Helvie, Pingping Mao, Flora Luo, Dewey Kim, Maxwell R. Lloyd, Jorge E. Buendia-Buendia, Gabriela N. Johnson, Xueqian Gong, Ofir Cohen, Seth A. Wander
Figure S8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::015e896eb128c33df61fd5df03da0d7d
https://doi.org/10.1158/2159-8290.22535357
https://doi.org/10.1158/2159-8290.22535357
Autor:
Nikhil Wagle, Sean G. Buchanan, Nancy U. Lin, Sara M. Tolaney, Eric P. Winer, Levi A. Garraway, Jill D. Kremer, Melissa E. Hughes, Gerald Batist, Quincy S. Chu, Gerard J. Oakley, Patricia S. Smith, John R. Stille, Valerie M. Jansen, Chunping Yu, Xiang S. Ye, Lacey M. Litchfield, Ricardo Martinez, Stephen H. Parsons, Adrienne G. Waks, Utthara Nayar, Kailey J. Kowalski, Karla Helvie, Pingping Mao, Flora Luo, Dewey Kim, Maxwell R. Lloyd, Jorge E. Buendia-Buendia, Gabriela N. Johnson, Xueqian Gong, Ofir Cohen, Seth A. Wander
Figure S5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001f147702d0ceaf79fb4c743f76c6cc
https://doi.org/10.1158/2159-8290.22535366
https://doi.org/10.1158/2159-8290.22535366
Autor:
Nikhil Wagle, Sean G. Buchanan, Nancy U. Lin, Sara M. Tolaney, Eric P. Winer, Levi A. Garraway, Jill D. Kremer, Melissa E. Hughes, Gerald Batist, Quincy S. Chu, Gerard J. Oakley, Patricia S. Smith, John R. Stille, Valerie M. Jansen, Chunping Yu, Xiang S. Ye, Lacey M. Litchfield, Ricardo Martinez, Stephen H. Parsons, Adrienne G. Waks, Utthara Nayar, Kailey J. Kowalski, Karla Helvie, Pingping Mao, Flora Luo, Dewey Kim, Maxwell R. Lloyd, Jorge E. Buendia-Buendia, Gabriela N. Johnson, Xueqian Gong, Ofir Cohen, Seth A. Wander
Figure S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96ed46edadca7e07fadb84a63501aae8
https://doi.org/10.1158/2159-8290.22535369
https://doi.org/10.1158/2159-8290.22535369
Autor:
Robert M. Campbell, Sean G. Buchanan, James R. Henry, David A. Barda, Gregory D. Plowman, Christoph Reinhard, Bharvin K.R. Patel, Xiang S. Ye, Maria Jose Lallena, Emiko L. Kreklau, Shripad V. Bhagwat, Ricardo Martinez, Matthew Z. Dieter, Bartley W. Halstead, Jennie L. Walgren, Jason R. Manro, Phillip W. Iversen, Michele S. Dowless, Louis F. Stancato, Shobha Bhattachar, Shaoyou Chu, Amit Aggarwal, Yue W. Webster, Yuewei Qian, Li-Chun Chio, Mark S. Marshall, Richard P. Beckmann, Jack A. Dempsey, Darlene S. Barnard, Robert D. Van Horn, Gregory P. Donoho, Andrew Capen, Robert T. Foreman, Sarah M. Bogner, Yi Zeng, Yanzhu Yang, Sonya C. Chapman, Yu-Hua Hui, Carmen Baquero, Karsten Boehnke, Carlos Marugán, Huimin Bian, Xueqian Gong, Raquel Torres, Lei Yan, Jian Du
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ab9e588f7270d239b69faebcc24e90
https://doi.org/10.1158/1535-7163.22506969.v1
https://doi.org/10.1158/1535-7163.22506969.v1
Autor:
Xiang S. Ye, Yong Wang, Juan A. Velasco, Courtney Tate, James J. Starling, Louis F. Stancato, Chuan Shih, Susan E. Pratt, Stephen H. Parsons, Songqing Na, Denis McCann, Mary Mader, Enrique Jambrina, Jeremy R. Graff, Raymond Gilmour, Alfonso De Dios, Edward M. Chan, Harold B. Brooks, Nathan A. Brooks, Bryan D. Anderson, Robert M. Campbell
p38α mitogen-activated protein kinase (MAPK) is activated in cancer cells in response to environmental factors, oncogenic stress, radiation, and chemotherapy. p38α MAPK phosphorylates a number of substrates, including MAPKAP-K2 (MK2), and regulates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22628225105d10e01b1823421dc49781
https://doi.org/10.1158/1535-7163.c.6536578.v1
https://doi.org/10.1158/1535-7163.c.6536578.v1
Autor:
Robert M. Campbell, Sean G. Buchanan, James R. Henry, David A. Barda, Gregory D. Plowman, Christoph Reinhard, Bharvin K.R. Patel, Xiang S. Ye, Maria Jose Lallena, Emiko L. Kreklau, Shripad V. Bhagwat, Ricardo Martinez, Matthew Z. Dieter, Bartley W. Halstead, Jennie L. Walgren, Jason R. Manro, Phillip W. Iversen, Michele S. Dowless, Louis F. Stancato, Shobha Bhattachar, Shaoyou Chu, Amit Aggarwal, Yue W. Webster, Yuewei Qian, Li-Chun Chio, Mark S. Marshall, Richard P. Beckmann, Jack A. Dempsey, Darlene S. Barnard, Robert D. Van Horn, Gregory P. Donoho, Andrew Capen, Robert T. Foreman, Sarah M. Bogner, Yi Zeng, Yanzhu Yang, Sonya C. Chapman, Yu-Hua Hui, Carmen Baquero, Karsten Boehnke, Carlos Marugán, Huimin Bian, Xueqian Gong, Raquel Torres, Lei Yan, Jian Du
Although Aurora A, B, and C kinases share high sequence similarity, especially within the kinase domain, they function distinctly in cell-cycle progression. Aurora A depletion primarily leads to mitotic spindle formation defects and consequently prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0aca539a9e32036f4566410352eeff32
https://doi.org/10.1158/1535-7163.c.6538536.v1
https://doi.org/10.1158/1535-7163.c.6538536.v1