Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Xiang Ju Wang"'
Autor:
Andrew Tuplin, Jody Hobson-Peters, Xiang Ju Wang, Andrii Slonchak, Pullinger B, Rhys Parry, Buck Tf, Colmant Amg, Jessica J. Harrison, Alexander A. Khromykh, Francisco J. Torres, Sng Jdj, Roy A. Hall
Publikováno v:
Nature Communications. 13
Insect-specific flaviviruses (ISFs) circulate in nature due to vertical transmission in mosquitoes and do not infect vertebrates. ISFs include two distinct lineages – classical ISFs (cISFs) that evolved independently and dual host associated ISFs (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033b475f9d318bd2a33266a52813d5be
https://doi.org/10.1038/s41467-022-28977-3
https://doi.org/10.1038/s41467-022-28977-3
Autor:
Xiang Ju. Wang
Kunjin virus (KUNV) is an Australian Flavivirus that very rarely causes disease in humans. West Nile virus (WNV) infects the central nervous system and causes severe disease primarily in humans. KUNV shares a high degree of homology and pathogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81b23e5ad412b7388e862eb2bae6e3ca
https://doi.org/10.14264/uql.2019.481
https://doi.org/10.14264/uql.2019.481
Autor:
Andreas Suhrbier, Erik Rollman, Vlad Mokhonov, Viv Peut, Xiang Ju Wang, Ekaterina I. Mokhonova, Alexander A. Khromykh, Sheilajen Alcantara, Caroline S. Fernandez, Kim Wilson, Liyen Loh, Rosemarie D. Mason, Robert De Rose, Stephen J. Kent, Jeanette C. Reece
Publikováno v:
Virology. 374:528-534
Persistent gag-specific T cell immunity would be a useful component of an effective HIV vaccine. The Flavivirus Kunjin replicon was previously engineered to persistently express HIV gag and was shown to induce protective responses in mice. We evaluat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd54aa0d3df1cd08a31bb8d3c0ab3678
https://doi.org/10.1016/j.virol.2008.01.006
https://doi.org/10.1016/j.virol.2008.01.006
Publikováno v:
Journal of Virology. 80:2396-2404
Alpha/beta interferons (IFN-α/β) are key mediators of the innate immune response against viral infection. The ability of viruses to circumvent IFN-α/β responses plays a crucial role in determining the outcome of infection. In a previous study usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e3e35ceb0ab989111f37e45a5b0e42
https://doi.org/10.1128/jvi.80.5.2396-2404.2006
https://doi.org/10.1128/jvi.80.5.2396-2404.2006
Autor:
Alexander A. Khromykh, Vladislav V. Mokhonov, Xiang Ju Wang, Wen Jun Liu, Richard E. Randall, Pei Yong Shi
Publikováno v:
Journal of Virology. 79:1934-1942
The interferon (IFN) response is the first line of defense against viral infections, and the majority of viruses have developed different strategies to counteract IFN responses in order to ensure their survival in an infected host. In this study, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47baf4d953115a5a8c8a287b8fc5f9a3
https://doi.org/10.1128/jvi.79.3.1934-1942.2005
https://doi.org/10.1128/jvi.79.3.1934-1942.2005
Autor:
Richard Linedale, Michael Jacobs, Itaru Anraku, Andreas Suhrbier, Xiang Ju Wang, Wen Jun Liu, Alexander A. Khromykh, Pei Yong Shi, Thuy T. Le, Andrew D. Davidson, Tracey J. Harvey
Publikováno v:
Journal of Virology. 78:531-538
We have previously developed replicon vectors derived from the Australian flavivirus Kunjin that have a unique noncytopathic nature and have been shown to direct prolonged high-level expression of encoded heterologous genes in vitro and in vivo and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b5e5655e62cc8c7755ece5e0eeb8592
https://doi.org/10.1128/jvi.78.1.531-538.2004
https://doi.org/10.1128/jvi.78.1.531-538.2004
Autor:
Paweena Rattanasena, Thuy T. Le, Andreas Suhrbier, Joy Gardner, Alexander A. Khromykh, Itaru Anraku, Xiang Ju Wang
Publikováno v:
Immunology and cell biology. 89(3)
Recombinant Kunjin replicon virus-like particle (VLP), vaccinia virus (rVV) and DNA vaccines were tested in a large series of prime-boost vaccinations using interferon (IFN)γ ELISPOT assays that reflected effector (E), effector memory (EM) and centr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::517b32719e205b4cef9fb74b9c8feb4a
https://pubmed.ncbi.nlm.nih.gov/20680025
https://pubmed.ncbi.nlm.nih.gov/20680025
Autor:
Thuy T. Le, Itaru Anraku, Wen Jun Liu, Gorben P. Pijlman, Leonie Smeenk, Xiang Ju Wang, Alexander A. Khromykh, Wayne A. Schroder, J. De Vrij, Andreas Suhrbier, Diem Hoang-Le
Publikováno v:
Gene Therapy 16 (2009)
Gene Therapy, 16, 190-199
Gene Therapy, 16, 190-199
We have recently developed a non-cytopathic RNA replicon-based viral vector system based on the flavivirus Kunjin. Here, we illustrate the utility of the Kunjin replicon system for gene therapy. Intra-tumoral injections of Kunjin replicon virus-like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea195652f171a29b8d5dbb6cd13c959a
https://research.wur.nl/en/publications/a-kunjin-replicon-vector-encoding-granulocyte-macrophage-colony-s
https://research.wur.nl/en/publications/a-kunjin-replicon-vector-encoding-granulocyte-macrophage-colony-s
Publikováno v:
Journal of virology. 78(22)
The establishment of persistent noncytopathic replication by replicon RNAs of a number of positive-strand RNA viruses usually leads to generation of adaptive mutations in nonstructural genes. Some of these adaptive mutations (e.g., in hepatitis C vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f67253d71e9517436b262870920275c6
https://pubmed.ncbi.nlm.nih.gov/15507609
https://pubmed.ncbi.nlm.nih.gov/15507609
Autor:
Rattanasena, Paweena, Anraku, Itaru, Gardner, Joy, Le, Thuy T., Xiang Ju Wang, Khromykh, Alexander A., Suhrbier, Andreas
Publikováno v:
Immunology & Cell Biology; Mar2011, Vol. 89 Issue 3, p426-436, 11p, 7 Graphs