Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Xiang Dong, Sun"'
Autor:
Zi-Yang Liu, Yuan-Quan Li, Die-Lin Wang, Ying Wang, Wan-Ting Qiu, Yu-Yang Qiu, He-Lin Zhang, Qiang-Long You, Shi-min Liu, Qiu-Ni Liang, Er-Jian Wu, Bing-Jie Hu, Xiang-Dong Sun
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Background Human patients often experience an episode of serious seizure activity, such as status epilepticus (SE), prior to the onset of temporal lobe epilepsy (TLE), suggesting that SE can trigger the development of epilepsy. Yet, the unde
Externí odkaz:
https://doaj.org/article/e208833a4391498a9b5dd818bf681600
Autor:
Jie Huang, Yan-Yan Zhang, Yu-Yang Qiu, Shan Yao, Wan-Ting Qiu, Jin-Lin Peng, Yuan-Quan Li, Qiang-Long You, Cui-Hong Wu, Er-Jian Wu, Jin Wang, Yan-Ling Zhou, Yu-Ping Ning, Hong-Sheng Wang, Wen-Bing Chen, Bing-Jie Hu, Youtan Liu, Xiang-Dong Sun
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113905- (2024)
Summary: Motivation-driven mating is a basic affair for the maintenance of species. However, the underlying molecular mechanisms that control mating motivation are not fully understood. Here, we report that NRG1-ErbB4 signaling in the medial amygdala
Externí odkaz:
https://doaj.org/article/61d914530c4a4f569396c49faeeb745c
Autor:
Miao-Miao Lv, Xiang-Dong Sun, Zhen Jin, Hai-Rong Wu, Ming-Tao Li, Gui-Quan Sun, Xin Pei, Yu-Tong Wu, Ping Liu, Li Li, Juan Zhang
Publikováno v:
One Health, Vol 17, Iss , Pp 100615- (2023)
Rabies is an acute zoonotic infectious disease caused by rabies virus. In 2015, the World Health Organization proposed the goal of eliminating dog-induced human rabies by 2030. In response to this goal positively, China has been dedicated to the cont
Externí odkaz:
https://doaj.org/article/664869fc12c84ba4b9b081f5fd45414b
Autor:
Shan Yao, Min-Dong Xu, Ying Wang, Shen-Ting Zhao, Jin Wang, Gui-Fu Chen, Wen-Bing Chen, Jian Liu, Guo-Bin Huang, Wen-Juan Sun, Yan-Yan Zhang, Huan-Li Hou, Lei Li, Xiang-Dong Sun
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
The role of glycolysis in depression is unclear. Here the authors report a glycolytic deficit under social stress and demonstrate that astrocytic LDHA affects neuronal excitability and depressive-like behaviours via lactate homeostasis in mice.
Externí odkaz:
https://doaj.org/article/d2df2840bdd647cd8bb7bb8ce72c67aa
Autor:
Feng Gao, Jie Huang, Guo-Bin Huang, Qiang-Long You, Shan Yao, Shen-Ting Zhao, Jian Liu, Cui-Hong Wu, Gui-Fu Chen, Shi-Min Liu, Zongyan Yu, Yan-Ling Zhou, Yu-Ping Ning, Shenquan Liu, Bing-Jie Hu, Xiang-Dong Sun
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 9 (2023)
Chronic pain can cause both hyperalgesia and anxiety symptoms. However, how the two components are encoded in the brain remains unclear. The prelimbic cortex (PrL), a critical brain region for both nociceptive and emotional modulations, serves as an
Externí odkaz:
https://doaj.org/article/d3f04cad1c8e4cd585eb54e45f1c69a6
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Externí odkaz:
https://doaj.org/article/b8b92b8582e24b0fbd0cc29891a73625
Autor:
Jin Wang, Jie Huang, Shan Yao, Jia-Hui Wu, Hui-Bin Li, Feng Gao, Ying Wang, Guo-Bin Huang, Qiang-Long You, Jianhua Li, Xiaohui Chen, Xiang-Dong Sun
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Background The ketogenic diet (KD)has been considered an effective treatment for epilepsy, whereas its underlying mechanisms remain obscure. We have previously reported that the KD feeding increased Neuregulin 1 (NRG1) expression in the hipp
Externí odkaz:
https://doaj.org/article/cdf6ffd71b0940b18bae8a17ea04cd55
Autor:
Jin Wang, Jie Huang, Yuan-Quan Li, Shan Yao, Cui-Hong Wu, Ying Wang, Feng Gao, Min-Dong Xu, Guo-Bin Huang, Chang-Qin Zhao, Jia-Hui Wu, Yun-Long Zhang, Renjie Jiao, Zi-Hao Deng, Wei Jie, Hui-Bin Li, Aiguo Xuan, Xiang-Dong Sun
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Background The ketogenic diet (KD) has been recognized as a potentially effective therapy to treat neuropsychiatric diseases, including epilepsy. Previous studies have indicated that KD treatment elevates γ-Amino butyric acid (GABA) levels
Externí odkaz:
https://doaj.org/article/3193745eefaf4f668da2f48a615d6f01
ATP9A deficiency causes ADHD and aberrant endosomal recycling via modulating RAB5 and RAB11 activity
Autor:
Tian Meng, Xiaoting Chen, Zhengjie He, Haofeng Huang, Shiyin Lin, Kunru Liu, Guo Bai, Hao Liu, Mindong Xu, Haixia Zhuang, Yunlong Zhang, Ahmed Waqas, Qian Liu, Chuan Zhang, Xiang-Dong Sun, Huansen Huang, Muhammad Umair, Yousheng Yan, Du Feng
Publikováno v:
Molecular Psychiatry. 28:1219-1231
ATP9A, a lipid flippase of the class II P4-ATPases, is involved in cellular vesicle trafficking. Its homozygous variants are linked to neurodevelopmental disorders in humans. However, its physiological function, the underlying mechanism as well as it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f488900cce0e9fb9fbb1981eddd124
https://doi.org/10.1038/s41380-022-01940-w
https://doi.org/10.1038/s41380-022-01940-w
Autor:
Feng Gao, Jie Huang, Yan-Fei Guan, Guo-Bin Huang, Wen-Jing Li, Xi-Yi He, Zi-Cong Qiu, Yun-Long Zhang, Shen-Ting Zhao, Jianhua Li, Aiguo Xuan, Xiang-Dong Sun
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Fear extinction remains an unresolved challenge for behavioral exposure therapy in patients with post-traumatic stress disorder (PTSD). Previous reports have suggested that social support from either familiar or unfamiliar same-sex partners is benefi
Externí odkaz:
https://doaj.org/article/97ab2043dc8c487da4fd7b8f5784a5fa