Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Xiang‐Guo Hu"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract N-Glycosylated heterocycles play important roles in biological systems and drug development. The synthesis of these compounds heavily relies on ionic N-glycosylation, which is usually constrained by factors such as labile glycosyl donors, pr
Externí odkaz:
https://doaj.org/article/0d1e767801134613b20cf25f16ba1a34
Autor:
Ruochen Lan, Xiang‐Guo Hu, Jingyu Chen, Xingping Zeng, Xinyu Chen, Tongji Du, Xinyue Song, Huai Yang
Publikováno v:
Responsive Materials, Vol 2, Iss 1, Pp n/a-n/a (2024)
Abstract Liquid crystal polymers (LCPs) have gained tremendous attention in recent years due to their great potentials from fabrication of responsive actuators and sensors to construction of intelligent soft robotic and light modulators. However, con
Externí odkaz:
https://doaj.org/article/8e55a70fd4834b2fb6f2904f9b0883ec
Autor:
Raju Cheerlavancha, Ahmed Ahmed, Yun Cheuk Leung, Aggie Lawer, Qing-Quan Liu, Marina Cagnes, Hee-Chan Jang, Xiang-Guo Hu, Luke Hunter
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 2316-2325 (2017)
Backbone-extended amino acids have a variety of potential applications in peptide and protein science, particularly if the geometry of the amino acid is controllable. Here we describe the synthesis of δ-amino acids that contain three vicinal C–F b
Externí odkaz:
https://doaj.org/article/8f6f4ba5619d414e9591e238346ecde5
Autor:
Xiang-Guo Hu, Luke Hunter
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 2696-2708 (2013)
The stereoselective incorporation of fluorine atoms into N-heterocycles can lead to dramatic changes in the molecules’ physical and chemical properties. These changes can be rationally exploited for the benefit of diverse fields such as medicinal c
Externí odkaz:
https://doaj.org/article/8112659e8aa44570bd95403acc9a408f
Autor:
Amber L. Thompson, Agnieszka Michalik, Robert J. Nash, Francis X. Wilson, Renate van Well, Peter Johnson, George W. J. Fleet, Chu-Yi Yu, Xiang-Guo Hu, Richard I. Cooper, David J. Watkin
Publikováno v:
Acta Crystallographica Section E, Vol 65, Iss 11, Pp o2904-o2905 (2009)
X-ray crystallographic analysis of the title hydrobromide salt, C10H20N+·Br−, of (1R,2S,3R,5R,8aR)-3-hydroxymethyl-5-methyloctahydroindolizine-1,2-diol defines the absolute and relative stereochemistry at the five chiral centres in steviamine, a n
Externí odkaz:
https://doaj.org/article/5291fcab05ff425dbeb8474867a68d7c
Publikováno v:
Organic Letters; 7/26/2024, Vol. 26 Issue 29, p6225-6229, 5p
Publikováno v:
Organic Letters. 24:9130-9134
We have developed a dual copper/photoredox-catalyzed approach for the construction of the P(O)-N bond from commercially available aromatic amines and P(O)-H compounds. This metallaphotoredox method avoids toxic or corrosive reagents and does not requ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8f11200d63329173746bfae1d0d9e0
https://doi.org/10.1021/acs.orglett.2c03860
https://doi.org/10.1021/acs.orglett.2c03860
Publikováno v:
Green Chemistry. 24:8280-8291
A metal-free, photo-mediated method for the synthesis of C2-phosphorylated carbohydrates has been developed, whose reaction mechanism consists of the reduction of a glycosyl radical to a glycosyl anion.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::920af6b780fa923a3d22059089b43a15
https://doi.org/10.1039/d2gc01513g
https://doi.org/10.1039/d2gc01513g
Publikováno v:
The Journal of Organic Chemistry. 87:1272-1284
Inspired by Roush's pioneering work on rare sugars, we have developed a scalable, stereoselective, de novo synthesis of orthogonally protected C2-fluoro digitoxose and cymarose, utilizing Sharpless kinetic resolution and organocatalytic fluorination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a65dc17e819c99b6213b1dce3389dcb2
https://doi.org/10.1021/acs.joc.1c02592
https://doi.org/10.1021/acs.joc.1c02592
Publikováno v:
Organic Letters. 23:8899-8904
We have developed a stereoselective, glycosyl radical-based method for the synthesis of C-alkyl glycosides via a photomediated defluorinative gem-difluoroallylation reaction. We demonstrate for the first time that glycosyl radicals, generated from gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a18d8ad2a872295270c72582d0184dcd
https://doi.org/10.1021/acs.orglett.1c03390
https://doi.org/10.1021/acs.orglett.1c03390