Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Xianfeng Zha"'
Autor:
Yun Tian, Jiafan Guo, Lipeng Mao, Zhixi Chen, Xingwei Zhang, Yangqiu Li, Yikai Zhang, Xianfeng Zha, Oscar Junhong Luo
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Background Quiescent self-renewal of leukemia stem cells (LSCs) and resistance to conventional chemotherapy are the main factors leading to relapse of acute myeloid leukemia (AML). Alpha-enolase (ENO1), a key glycolytic enzyme, has been show
Externí odkaz:
https://doaj.org/article/1b76bb0bad774a7c84ce0c6890428e9f
Autor:
Letong Cai, Wenpu Lai, Danlin Yao, Yinfeng Gu, Chaofeng Liang, Lian Liu, Jing Lai, Zhi Yu, Xianfeng Zha, Xibao Yu, Xiuli Wu, Shaohua Chen, Oscar Junhong Luo, Yangqiu Li, Chunyan Wang, Pengfei Qin, Xin Huang, Ling Xu
Publikováno v:
Blood Science, Vol 6, Iss 3, p e00194 (2024)
Tissue-resident memory T (TRM) cells infiltrating solid tumors could influence tumor progression and the response to immune therapies. However, the proportion and prognostic value of TRM cells in the bone marrow (BM) of patients with acute myeloid le
Externí odkaz:
https://doaj.org/article/d300d769922143ca97253538e7515d90
Autor:
Xibao Yu, Yuchen Li, Pengyue Yang, Yan Wang, Xuan Liu, Letong Cai, Jing Lai, Yue Zhang, Xianfeng Zha, Grzegorz Krzysztof Przybylski, Ling Xu, Yangqiu Li
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 2, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/2bd41c855cc74585bd5067a0b9c4393b
Autor:
Shuxin Huang, Yujie Zhao, Wenpu Lai, Jiaxiong Tan, Xue Zheng, Xianfeng Zha, Yangqiu Li, Shaohua Chen
Publikováno v:
Cancer Biology & Therapy, Vol 24, Iss 1 (2023)
ABSTRACTWith the success of immune checkpoint inhibitors (ICI), such as anti- programmed death-1 (PD-1) antibody for solid tumors and lymphoma immunotherapy, a number of clinical trials with ICIs have been attempted for acute myeloid leukemia (AML) i
Externí odkaz:
https://doaj.org/article/eb6965abad314310a9783cf52ddedd15
Autor:
Yikai Zhang, Xiangbo Zeng, Xianfeng Zha, Jing Lai, Guangxiao Tan, Shaohua Chen, Xibao Yu, Yangqiu Li, Ling Xu
Publikováno v:
Hematology, Vol 27, Iss 1, Pp 523-529 (2022)
Objective T cell dysfunction is a common characteristic of patients with myeloid leukemia and is closely related to clinical efficacy and prognosis. In order to clarify the mechanisms leading to the T cell dysfunction, we characterized the gene expre
Externí odkaz:
https://doaj.org/article/523a44953cf84dad98ca6d920916c39d
Analysis on the main structural factors controlling rockfalls in downtown of Ansai, Shaanxi Province
Autor:
Hu WANG, Huaijun GUO, Yimin WANG, Qiang XUE, Kai WANG, Xianfeng ZHA, Xiaoyong WANG, Pingping SUN, Xiujuan CHENG
Publikováno v:
Zhongguo dizhi zaihai yu fangzhi xuebao, Vol 33, Iss 3, Pp 51-60 (2022)
An anticlinal structure with an axis plane along Yanhe river and a strike of about 330° is developed in the bedrock strata within the main urban area of AnSai County. In the bedrock strata, there are generally two groups of tensile joints parallel t
Externí odkaz:
https://doaj.org/article/ec5e84d9a0f449ec91f979187a22fefc
Autor:
Danlin Yao, Jing Lai, Yuhong Lu, Jun Zhong, Xianfeng Zha, Xin Huang, Lian Liu, Xiangbo Zeng, Shaohua Chen, Jianyu Weng, Xin Du, Yangqiu Li, Ling Xu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundImmunological phenotypes and differentiation statuses commonly decide the T cell function and anti-tumor ability. However, little is known about these alterations in CML patients.MethodHere, we investigated the immunologic phenotypes (CD38/
Externí odkaz:
https://doaj.org/article/750a7db16df848c1924aa127a4575481
Autor:
Wenpu Lai, Xiaofang Wang, Lian Liu, Ling Xu, Lipeng Mao, Jiaxiong Tan, Xianfeng Zha, Huien Zhan, Wen Lei, Yu Lan, Guobing Chen, Yangqiu Li, Oscar Junhong Luo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionThe character and composition of leukemia-related T cells are closely related to the treatment response and prognosis for patients. Though B cell-acute lymphoblastic leukemia (B-ALL) patients have benefited from immune-based approaches, s
Externí odkaz:
https://doaj.org/article/66dd6f4ec8bf49a98bff5a83de614b62
Autor:
Shuxin Huang, Yujie Zhao, Pengjun Liao, Jinghua Wang, Zhiyan Li, Jiaxiong Tan, Xianfeng Zha, Shaohua Chen, Yangqiu Li, Liye Zhong
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
V-type immunoglobulin domain-containing suppressor of T cell activation (VISTA) is considered as an immunosuppressive factor and potential therapeutic target for anticancer therapy. However, little is known about VISTA expression and its role in immu
Externí odkaz:
https://doaj.org/article/5110badacf4846429b369b7a516e343e
Autor:
Xiaofang Wang, Yanjuan Chen, Zongcheng Li, Bingyan Huang, Ling Xu, Jing Lai, Yuhong Lu, Xianfeng Zha, Bing Liu, Yu Lan, Yangqiu Li
Publikováno v:
Advanced Science, Vol 8, Iss 19, Pp n/a-n/a (2021)
Abstract Characterization of functional T cell clusters is key to developing strategies for immunotherapy and predicting clinical responses in leukemia. Here, single‐cell RNA sequencing is performed with T cells sorted from the peripheral blood of
Externí odkaz:
https://doaj.org/article/3a3127d68e2442cbbd8f891e713854a2