Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Xianfei He"'
Autor:
Hang Ke, Tao Yang, Faming Zhang, Cen Chen, Jingjing Wang, Jinping Liu, Xiaoyu An, Lingxin Xiong, Xianfei He, Lei Zhang, Qi-Xiang Li
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Certain immune-checkpoint inhibitors have a narrow therapeutic window (TW) as cancer therapeutics, and engineered dual-/multi-targeting agents could potentially widen the TW to bring true clinical benefits. We report a new rationally-designe
Externí odkaz:
https://doaj.org/article/ca9ac7b4a1eb404fab5c23f987819202
Publikováno v:
Thoracic Cancer, Vol 12, Iss 12, Pp 1900-1908 (2021)
Abstract Background The cylindromatosis (CYLD) tumor suppressor is a microtubule‐associated deubiquitinase that plays a critical role in the regulation of cell signaling and contributes to a variety of physiological and pathological processes. Howe
Externí odkaz:
https://doaj.org/article/b12788e18d7248bba75c9ac9d6eaf4e1
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94496 (2014)
The innate immune system is the first line of host defense against infection and involves several different cell types. Here we investigated the role of the phosphatidylinositol 3 kinase (PI3K) signaling pathway in innate immune cells. By blocking th
Externí odkaz:
https://doaj.org/article/8f87e47bc79d4049b8cb76d5517fa9d8
Autor:
Xiaoyu An, Henry Li, Hang Ke, Lingxin Xiong, Faming Zhang, Mingfa Zang, Xiaolong Tu, Jingjing Wang, Demi Liu, Cen Chen, Cunxiang Ju, Xianfei He, Lei Zhang
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9b8e22fb2908b814376fbae84b47633
https://doi.org/10.1136/jitc-2022-sitc2022.0491
https://doi.org/10.1136/jitc-2022-sitc2022.0491
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::755bc0eb015a7269301bc47a9185a4e7
https://doi.org/10.1136/jitc-2022-sitc2022.0106
https://doi.org/10.1136/jitc-2022-sitc2022.0106
Publikováno v:
Thoracic Cancer
Thoracic Cancer, Vol 12, Iss 12, Pp 1900-1908 (2021)
Thoracic Cancer, Vol 12, Iss 12, Pp 1900-1908 (2021)
Background The cylindromatosis (CYLD) tumor suppressor is a microtubule‐associated deubiquitinase that plays a critical role in the regulation of cell signaling and contributes to a variety of physiological and pathological processes. However, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64ba2bb323b23b7c979574568a677bf
https://doi.org/10.1111/1759-7714.13973
https://doi.org/10.1111/1759-7714.13973
Autor:
Tao Yang, Rongfei Lu, Xiaofei Xu, Likun Zhang, Dawei Wang, Xinhe Feng, Xiaoyu An, Jessie (Jingjing) Wang, Xianfei He, Carl K. Edwards
Publikováno v:
Cancer Research. 83:5133-5133
Background. Th2 cytokines (e.g. IL-4, IL-5, IL13) drive defined allergic reactions and various autoimmune and inflammatory diseases including atopic dermatitis (AD), asthma and rhinitis. IL-4Ra is a receptor shared by both IL-4 and IL-13, thus blocki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ce7e5f2004800d4c0cacdf431f7cefe
https://doi.org/10.1158/1538-7445.am2023-5133
https://doi.org/10.1158/1538-7445.am2023-5133
Publikováno v:
Cancer Research. 82:615-615
BACKGROUND: Immune checkpoint inhibitors (ICIs) have revolutionized the cancer therapy landscape in recent years. Despite the success of the checkpoint blockade strategies targeting cytotoxic T lymphocyte antigen 4 (CTLA-4) and programmed death recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e2dc219bdad7f11d1bb36deb5780123
https://doi.org/10.1158/1538-7445.am2022-615
https://doi.org/10.1158/1538-7445.am2022-615
Autor:
Lihong Yang, Qingchao Li, Te Li, Tao Zhong, Wei Xie, Yan Zhang, Min Liu, Jun Zhou, Song Yang, Jie Feng, Dengwen Li, Xianfei He, Songbo Xie
Publikováno v:
Experimental cell research. 387(1)
Microtubule-binding proteins provide an alternative and vital pathway to the functional diversity of microtubules. Considerable work is still required to understand the complexities of microtubule-associated cellular processes and to identify novel m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b75ce3958aa1a454bd2c31d30640ffe
https://pubmed.ncbi.nlm.nih.gov/31838060
https://pubmed.ncbi.nlm.nih.gov/31838060
Autor:
Ruilin Sun, Henry Q. X. Li, Daniel Xianfei He, Annie Xiaoyu An, Chenpan Nie, Cunxiang Ju, Davy Xuesong Ouyang, Lei Zheng, Mingkun Zhang
Publikováno v:
Cancer Research. 80:5614-5614
Introduction: Ample clinical and preclinical evidence have shown the remarkable antitumor effects of anti-PD-1 antibodies. However, the fact that only around 20% of patients respond to anti-PD-1 immunotherapy indicates that additional inhibitory circ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba986f061ebcb71d265d5f4d51671862
https://doi.org/10.1158/1538-7445.am2020-5614
https://doi.org/10.1158/1538-7445.am2020-5614