Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Xiandong Dai"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Capsaicin derivatives with thiourea structure (CDTS) is highly noteworthy owing to its higher analgesic potency in rodent models and higher agonism in vitro. However, the direct synthesis of CDTS remains t one or more shortcomings. In this s
Externí odkaz:
https://doaj.org/article/a2db7ed134f0474f98d89941df925643
Publikováno v:
Molecules, Vol 28, Iss 3, p 1007 (2023)
Linaclotide is a 14-amino acid residue peptide approved by the FDA for the treatment of irritable bowel syndrome with constipation (IBS-C), which activates guanylate cyclase C to accelerate intestinal transit. Here we show a new method for the synthe
Externí odkaz:
https://doaj.org/article/38c1c2efbaa24a9d90cf5f5f80dd3514
Autor:
Penggang Han, Kang Wang, Xiandong Dai, Ying Cao, Shangyi Liu, Hui Jiang, Chongxu Fan, Wenjian Wu, Jisheng Chen
Publikováno v:
Marine Drugs, Vol 14, Iss 11, p 213 (2016)
μ-Conotoxin GIIIA, a peptide toxin isolated from Conus geographus, preferentially blocks the skeletal muscle sodium channel NaV1.4. GIIIA folds compactly to a pyramidal structure stabilized by three disulfide bonds. To assess the contributions of in
Externí odkaz:
https://doaj.org/article/ee52765094a84640aec119c6f50671f9
Publikováno v:
Protein and peptide letters. 29(1)
Background: Contryphan-Bt is a D-tryptophan-containing disulfide-constrained decapeptide recently isolated from the venom of Conus betulinus. The molecular targets of contryphans are controversial, and the identification of its interacting proteins m
Contryphan-Bt: A pyroglutamic acid containing conopeptide isolated from the venom of Conus betulinus
Autor:
Ying Cao, Shang-Yi Liu, Ge Yao, Chong-Xu Fan, Xiandong Dai, Wenjian Wu, Penggang Han, Ji-Sheng Chen
Publikováno v:
Toxicon. 135:17-23
A new member of the contryphans family was isolated from the venom of Conus betilinus, a vermivorous species distributed in the South China Sea. Its sequence, ZSGCO(D-W)KPWC-NH 2 (Z, pyroglutamic acid), was established by a combination of de novo MS/
Autor:
Shang-Yi Liu, Chong-Xu Fan, Kang Wang, Wenjian Wu, Ying Cao, Xiandong Dai, Penggang Han, Hui Jiang, Ji-Sheng Chen
Publikováno v:
Marine Drugs, Vol 14, Iss 11, p 213 (2016)
Marine Drugs; Volume 14; Issue 11; Pages: 213
Marine Drugs; Volume 14; Issue 11; Pages: 213
μ-Conotoxin GIIIA, a peptide toxin isolated from Conus geographus, preferentially blocks the skeletal muscle sodium channel NaV1.4. GIIIA folds compactly to a pyramidal structure stabilized by three disulfide bonds. To assess the contributions of in
Publikováno v:
Toxicon. 158:S73
Publikováno v:
Toxicon. 158:S76
Publikováno v:
Chinese Journal of Natural Medicines. 8:132-136
Autor:
Hui Jiang, Ji-Sheng Chen, Cheng-Zhong Wang, Cheng-Wu Chi, Chong-Xu Fan, Chenqi Xu, Xiandong Dai
Publikováno v:
Peptides. 27:682-689
Cone snails are tropical marine mollusks that envenomate prey with a complex mixture of neuropharmacologically active compounds for the purpose of feeding and defence, each evolved to act in a highly specific manner on different parts of the nervous