Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Xiandeng Li"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
ObjectiveAbdominal aortic aneurysm (AAA) is a life-threatening vascular condition. This study aimed to discover new indicators for the early detection of AAA and explore the possible involvement of immune cell activity in its development.MethodsSourc
Externí odkaz:
https://doaj.org/article/a5fd462dedc8473795e9dabfc97c72f1
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 168, Iss , Pp 115670- (2023)
Diabetic nephropathy (DN) is a severe complication of diabetes mellitus, posing significant challenges in terms of early prevention, clinical diagnosis, and treatment. Consequently, it has emerged as a major contributor to end-stage renal disease. Th
Externí odkaz:
https://doaj.org/article/76aa8e3ef12d4b03bd266648521e555f
Autor:
Yanting Zhou, Xiandeng Li, Peifang Luo, Huiting Chen, Yan Zhou, Xueting Zheng, Yuan Yin, Haoche Wei, Hongji Liu, Wen Xia, Mingsong Shi, Xiaoan Li
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
CDK4/6 plays a crucial role in various cancers and is an effective anticancer drug target. However, the gap between clinical requirements and approved CDK4/6 drugs is unresolved. Thus, there is an urgent need to develop selective and oral CDK4/6 inhi
Externí odkaz:
https://doaj.org/article/f5588207e8284824be612e0214ce23b7
Autor:
Xiaodong Xing, Xinzhu Liu, Xiandeng Li, Mi Li, Xian Wu, Xiaohui Huang, Ajing Xu, Yan Liu, Jian Zhang
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 7, Pp 1849-1863 (2025)
Spinal muscular atrophy is a devastating motor neuron disease characterized by severe cases of fatal muscle weakness. It is one of the most common genetic causes of mortality among infants aged less than 2 years. Biomarker research is currently recei
Externí odkaz:
https://doaj.org/article/30c8d4fbbeb544939878e685f329d4cd
Publikováno v:
Physiological Research; Oct2024, Vol. 73 Issue 5, p819-829, 11p
Autor:
Kongjun Liu, Wei Zheng, Yong Chen, Minghai Tang, Dan Li, Dexin Deng, Tao Yang, Chufeng Zhang, Jiang Liu, Xue Yuan, Mingsong Shi, Xiandeng Li, Yong Guo, Yanting Zhou, Min Zhao, Lijuan Chen
Publikováno v:
Journal of Medicinal Chemistry. 65:9893-9917
Nowadays, PI3Kδ-γ dual inhibitors have been approved for the treatment of B-cell malignancies. Dual inhibition of PI3Kδ and PI3Kγ represents a unique therapeutic opportunity and may confer greater benefits than either isoform inhibition alone in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::269879bbc679b6daec44c932658666f2
https://doi.org/10.1021/acs.jmedchem.2c00568
https://doi.org/10.1021/acs.jmedchem.2c00568
Cyclin-Dependent Kinase 4 and 6 Inhibitors as Breast Cancer Therapy: Research Progress and Prospects
Autor:
Xiandeng Li
Publikováno v:
Pharmaceutical Chemistry Journal. 56:71-77
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bdefa4fb346a3d694db7e9539a76575
https://doi.org/10.1007/s11094-022-02599-x
https://doi.org/10.1007/s11094-022-02599-x
Autor:
Suhong Fu, Yi Wen, Bin Peng, Minghai Tang, Mingsong Shi, Jiang Liu, Yingxue Yang, Wenting Si, Yong Guo, Xiandeng Li, Tingting Yan, Jie Kang, Heying Pei, Lijuan Chen
Publikováno v:
Bioorganic Chemistry. 137:106539
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a087e1c1b313d8a2fb757d2cefec97e1
https://doi.org/10.1016/j.bioorg.2023.106539
https://doi.org/10.1016/j.bioorg.2023.106539
Autor:
Huan Wang, Minghai Tang, Xiang Qiu, Yan Tan, Yong Guo, Kongjun Liu, Xiandeng Li, Wenshuang Wu, Li Wan
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 52(3)
The objective of this study was to identify metabolites of PD110 by UHPLC-Q-Exactive Plus MS and determine its metabolic pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae85ad2b87a6d646ebbf3f46a16fa57
https://pubmed.ncbi.nlm.nih.gov/35377274
https://pubmed.ncbi.nlm.nih.gov/35377274
Publikováno v:
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery. 28(15)
To analyze and summarize clinical characteristic, treatment scheme and survival rate of primary melanom in nasal cavity and sinus.We retrospectively analyzed the 9 patients with primary melanom in nasal cavity and sinus who in data proceed were treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::50400d37b42fbf06af73d2bdc1949d39
https://pubmed.ncbi.nlm.nih.gov/25322610
https://pubmed.ncbi.nlm.nih.gov/25322610