Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Xianai Xu"'
Autor:
Yoshiyuki Mizushina, Xianai Xu, Chikako Murakami, Toshio Okano, Masaharu Takemura, Hiromi Yoshida, Kengo Sakaguchi
Publikováno v:
Journal of Pharmacological Sciences, Vol 92, Iss 3, Pp 283-290 (2003)
As described previously (H. Togashi et al. Biochem Pharmacol. 1998;56:583–590), the irradiated products of provitamin D2 (ergosterol) inhibit the activities of eukaryotic DNA polymerases. In this report, therefore, we investigated whether vitamin D
Externí odkaz:
https://doaj.org/article/54dcc86120c0422baf720575370ef852
Autor:
Kiminori Matsubara, Kengo Sakaguchi, Chikako Murakami, Isoko Kuriyama, Xianai Xu, Norihisa Kato, Masahiko Oshige, Hiromi Yoshida, Yoshiyuki Mizushina, Masaharu Takemura
Publikováno v:
Biochemical and Biophysical Research Communications. 312:1025-1032
Vitamin B6 compounds such as pyridoxal 5′-phosphate (PLP), pyridoxal (PL), pyridoxine (PN), and pyridoxamine (PM), which reportedly have anti-angiogenic and anti-cancer effects, were thought to be inhibitors of some types of eukaryotic DNA polymera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ee43071f3a9f40ce48cfc4ff180cb49
https://doi.org/10.1016/j.bbrc.2003.11.027
https://doi.org/10.1016/j.bbrc.2003.11.027
Autor:
Chikako Murakami, Kenji Mori, Masahiko Oshige, Osamu Koiwai, Toyofumi Yamaguchi, Mineo Saneyoshi, Noriko Shimazaki, Hiromi Yoshida, Yoshiyuki Mizushina, Kengo Sakaguchi, Nobuyuki Kasai, Hirosato Takikawa, Fumio Sugawara, Xianai Xu
Publikováno v:
Journal of Biochemistry. 133:541-552
Hippospongic acid A (HA-A) is a novel natural triterpene metabolite that exhibits inhibitory activity against the gastrulation of starfish embryos isolated from a marine sponge, Hippospongia sp. We succeeded in chemically synthesizing the natural ena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a427af710dd27d8478b65808a5c6edf
https://doi.org/10.1093/jb/mvg070
https://doi.org/10.1093/jb/mvg070
Autor:
Hitomi Asahara, Atsushi Kato, Hiromi Yoshida, Yoshiyuki Mizushina, Kengo Sakaguchi, Xianai Xu, Fumio Sugawara, Nobuyuki Kasai, Masaharu Takemura, Naoki Asano, Stuart Linn
Publikováno v:
Biochemical and Biophysical Research Communications. 304:78-85
The pyrrolidine alkaloids mimicking the structures of pentose with nitrogen in the ring are known to be inhibitors of glycosidases. We report here that a compound belonging to this category is an inhibitor of eukaryotic DNA polymerases. Among the eig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f49b638d6c594650b48c2b341d301062
https://doi.org/10.1016/s0006-291x(03)00540-0
https://doi.org/10.1016/s0006-291x(03)00540-0
Autor:
Motohiko Ukiya, Kengo Sakaguchi, Isoko Kuriyama, Toshihiro Akihisa, Chikako Murakami, Xianai Xu, Yoshiyuki Mizushina, Hiromi Yoshida
Publikováno v:
Cancer science. 95(4)
Traditional Chinese medicinal plants are a treasure house for screening novel inhibitors of DNA polymerases and DNA topoisomerases from mammals; in the present study, nine lanostane-type triterpene acids were found in sclerotium of Poria cocos. Among
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e7ca9fbde91098d2fc12f3ec68908a8
https://pubmed.ncbi.nlm.nih.gov/15072595
https://pubmed.ncbi.nlm.nih.gov/15072595
Autor:
Kengo Sakaguchi, Miho Kawasaki, Naoki Maeda, Hideki Ichikawa, Chikako Murakami, Hiromi Yoshida, Fumio Sugawara, Masaharu Takemura, Xianai Xu, Yoshinobu Fukumori, Yoshiyuki Mizushina
Publikováno v:
Lipids. 38(10)
We reported previously that sulfoquinovosyl diacylglycerol and sulfoquinovosyl monoacylglycerol (SQDG/SQMG) are potent inhibitors of mammalian DNA polymerases and DNA topoisomerase II, and can be potent immunosuppressive agents and anticancer chemoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8a59330fb6d891e6f04ab08bc5b69a
https://pubmed.ncbi.nlm.nih.gov/14669972
https://pubmed.ncbi.nlm.nih.gov/14669972
Autor:
Yoshiyuki, Mizushina, Xianai, Xu, Kiminori, Matsubara, Chikako, Murakami, Isoko, Kuriyama, Masahiko, Oshige, Masaharu, Takemura, Norihisa, Kato, Hiromi, Yoshida, Kengo, Sakaguchi
Publikováno v:
Biochemical and biophysical research communications. 312(4)
Vitamin B(6) compounds such as pyridoxal 5(')-phosphate (PLP), pyridoxal (PL), pyridoxine (PN), and pyridoxamine (PM), which reportedly have anti-angiogenic and anti-cancer effects, were thought to be inhibitors of some types of eukaryotic DNA polyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e519aacc30bc1bbc30c8c97eb986c5e
https://pubmed.ncbi.nlm.nih.gov/14651974
https://pubmed.ncbi.nlm.nih.gov/14651974
Autor:
Hiromi Yoshida, Xianai Xu, Toshio Okano, Chikako Murakami, Kengo Sakaguchi, Yoshiyuki Mizushina, Masaharu Takemura
Publikováno v:
Journal of pharmacological sciences. 92(3)
As described previously (H. Togashi et al. Biochem Pharmacol. 1998;56:583-590), the irradiated products of provitamin D(2) (ergosterol) inhibit the activities of eukaryotic DNA polymerases. In this report, therefore, we investigated whether vitamin D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66bdfa2f8aba03507f9abd40a8e6b941
https://pubmed.ncbi.nlm.nih.gov/12890894
https://pubmed.ncbi.nlm.nih.gov/12890894
Autor:
Masaharu Takemura, Kengo Sakaguchi, Kazufumi Kuroda, Mineo Saneyoshi, Fumio Sugawara, Ryo Takeuchi, Hiromi Yoshida, Hitomi Asahara, Toyofumi Yamaguchi, Noriko Shimazaki, Osamu Koiwai, Xianai Xu, Yoshiyuki Mizushina, Stuart Linn, Masahiko Oshige
Sulphoquinovosyl diacylglycerol (SQDG) was reported as a selective inhibitor of eukaryotic DNA polymerases alpha and beta [Hanashima, Mizushina, Ohta, Yamazaki, Sugawara and Sakaguchi (2000) Jpn. J. Cancer Res. 91, 1073-1083] and an immunosuppressive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742ead40e9c5392b7d1847e5ae6a6507
https://europepmc.org/articles/PMC1223160/
https://europepmc.org/articles/PMC1223160/
Autor:
Hiromi Yoshida, Kengo Sakaguchi, Satoshi Nakazawa, Fumio Sugawara, Shinji Kamisuki, Ui Kanekazu, Xianai Xu, Takahiko Hada, Chikako Murakami, Yoshiyuki Mizushina, Taeko Kumagai, Naoki Maeda
Publikováno v:
Biochemical pharmacology. 65(2)
We purified the major glycolipids in the class of monogalactosyl diacylglycerol (MGDG), digalactosyl diacylglycerol (DGDG) and sulfoquinovosyl diacylglycerol (SQDG) from a green vegetable, spinach (Spinacia oleracea L.). MGDG was an inhibitor of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e48febf8b53c81a52cb96ac22d66b5a7
https://pubmed.ncbi.nlm.nih.gov/12504801
https://pubmed.ncbi.nlm.nih.gov/12504801