Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Xian-wei Ye"'
Publikováno v:
European Journal of Medical Research, Vol 28, Iss 1, Pp 1-7 (2023)
Abstract Background Hypomethylation of the perforin gene promoter in CD4 + T cells, inflammation and oxidative stress, might be involved in alveolar septal cell apoptosis associated with emphysema in rats. This study aimed to investigate the effects
Externí odkaz:
https://doaj.org/article/d2b0f8ba0bc4468cb6a97f1d5d81b91b
Autor:
Jia-jia Liu, Lin Liu, Hong-hong Mu, Jia-yi Li, Lin Xu, Yao-yao Wu, Ben-xue Li, Ye Zhang, Xiang-yan Zhang, Xian-wei Ye, Cheng Zhang
Publikováno v:
COPD, Vol 19, Iss 1, Pp 255-261 (2022)
Our previous study suggested that hypomethylation of perforin promoter of CD4 + T cells might be involved in the pathogenesis of autoimmune emphysema of rats. Whether transfer of this kind of cells hypomethylated in vitro into naive immunocompetent r
Externí odkaz:
https://doaj.org/article/7ff76013fde9443c99807eab9c570f73
Publikováno v:
Case Reports in Medicine, Vol 2011 (2011)
After early outbreaks in North America in April 2009, the pandemic influenza A (H1N1) virus spread rapidly around the world, and even some patients developed certain severe complications. We reported one case of hemophagocytic lymphohistiocytosis (HL
Externí odkaz:
https://doaj.org/article/7d6e5d1f2bd448d1b8fc27dd3501b9bf
Publikováno v:
Ultrasound.
Publikováno v:
Experimental and Therapeutic Medicine.
Obstructive sleep apnoea (OSA) is a very common sleep and breathing disorder that occurs in worldwide. It is important to develop a more effective treatment for OSA to overcome lung cell apoptosis during intermittent hypoxia (IH). A mitochondrial sep
Publikováno v:
The Clinical Respiratory Journal. 9:27-33
Objective Underlying mechanisms of non-small cell lung cancer (NSCLC) development remain poorly understood. miR-138 and 3-phosphoinositide-dependent protein kinase-1 (PDK1) have been reported to be involved in the genesis of NSCLC. The aim of this st
Autor:
Cheng Zhang, Ping Chen, Xu Mei, Min Yang, Xiang-Yan Zhang, Mu-Yun Yan, Lu Ping, Zhang-Hong Ou Yang, Xian-Wei Ye
Publikováno v:
Respirology. 19:376-381
Background and objective It is widely accepted that perforin regulatory elements are hypomethylated in CD4+ T cells from patients with active lupus, but whether this is the case in autoimmune emphysema is not known. Methods Twenty rats were randomly
Autor:
Bin Yu, Ying-Chao Duan, Hong-Min Liu, En Zhang, Meng-Meng Wang, Jin-Lian Ma, Yi-Chao Zheng, Jing-Li Ren, Xian-Wei Ye
Publikováno v:
Med. Chem. Commun.. 5:650-654
Two series of coumarin–1,2,3-triazole–dithiocarbamate hybrids were designed, synthesized and evaluated for their inhibitory activity towards lysine specific demethylase 1 (LSD1). Compounds 8a, 8d–8f, 8i–8l presented potent activity against ly
Autor:
Hong-Min Liu, Ying-Chao Duan, Yuan-Yuan Guan, Gai-Zhi Liu, Jiaxin Zheng, Meng-Meng Wang, Xian-Wei Ye, Yi-Chao Zheng, Xiao-Chen Li
Publikováno v:
European Journal of Medicinal Chemistry. 64:99-110
A series of novel 1,2,3-triazole–dithiocarbamate–urea hybrids were designed, synthesized and their antiproliferative activities against four selected human cancer cell lines were evaluated. The results showed that a number of the hybrids exhibite
Autor:
Yong-Cheng Ma, Ying-Chao Duan, Hong-Min Liu, Xian-Wei Ye, Meng-Meng Wang, En Zhang, Xiao-Jing Shi
Publikováno v:
European Journal of Medicinal Chemistry. 62:11-19
A series of novel 1,2,3-triazole-dithiocarbamate hybrids were designed, synthesized and evaluated for anticancer activity against four selected human tumor cell lines (MGC-803, MCF-7, PC-3, EC-109). Majority of the synthesized compounds exhibited mod