Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Xian-feng Cen"'
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116589- (2024)
Diabetic cardiomyopathy (DCM) is a common severe complication of diabetes that occurs independently of hypertension, coronary artery disease, and valvular cardiomyopathy, eventually leading to heart failure. Previous studies have reported that Tector
Externí odkaz:
https://doaj.org/article/93f75ea4e25647a6b126ec8c8d840fd1
Autor:
Yingying Guo, Xian-feng Cen, Dan Li, Hong-liang Qiu, Ya-jie Chen, Meng Zhang, Si-hui Huang, Hao Xia, Man Xu
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundChronic pressure overload triggers pathological cardiac hypertrophy that eventually leads to heart failure. Effective biomarkers and therapeutic targets for heart failure remain to be defined. The aim of this study is to identify key genes
Externí odkaz:
https://doaj.org/article/123ec5a0abfd4e519776d7b152ae74e3
Autor:
Man Xu, Ying-ying Guo, Dan Li, Xian-feng Cen, Hong-liang Qiu, Yu-lan Ma, Si-hui Huang, Qi-zhu Tang
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundDilated cardiomyopathy (DCM) is characterized by enlarged ventricular dimensions and systolic dysfunction and poor prognosis. Myocardial lipid metabolism appears abnormal in DCM. However, the mechanism of lipid metabolism disorders in DCM r
Externí odkaz:
https://doaj.org/article/6c732029a4a74661bc4ab1b3270f2094
Autor:
Li-Bo, Liu, Si-Hui, Huang, Hong-Liang, Qiu, Xian-Feng, Cen, Ying-Ying, Guo, Dan, Li, Yu-Lan, Ma, Man, Xu, Qi-Zhu, Tang
Publikováno v:
British Journal of Pharmacology. 179:4516-4533
Limonin, a naturally occurring tetracyclic triterpenoid, has extensive pharmacological effects. Its role in cardiac hypertrophy remains to be elucidated. We investigated its effects on cardiac hypertrophy along with the potential mechanisms involved.
Autor:
Dan, Li, Ying-Ying, Guo, Xian-Feng, Cen, Hong-Liang, Qiu, Si, Chen, Xiao-Feng, Zeng, Qian, Zeng, Man, Xu, Qi-Zhu, Tang
Publikováno v:
Acta Pharmacologica Sinica. 43:1989-2002
Inflammation and apoptosis are main pathological processes that lead to the development of cardiac hypertrophy. Lupeol, a natural triterpenoid, has shown anti-inflammatory and anti-apoptotic activities as well as potential protective effects on cardi
Autor:
Yingying Guo, Dan Li, Xian-feng Cen, Hong-liang Qiu, Yu-lan Ma, Yi Liu, Si-hui Huang, Li-bo Liu, Man Xu, Qi-Zhu Tang
Publikováno v:
Oxidative medicine and cellular longevity. 2022
An important pathophysiological consequence of pressure overload-induced cardiac hypertrophy is adverse cardiac remodeling, including structural changes in cardiomyocytes and extracellular matrix. Diosmetin (DIO), a monomethoxyflavone isolated from c