Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Xian-Zi Wen"'
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 22, Iss , Pp 1129-1141 (2020)
Long non-coding RNAs (lncRNAs) are characterized as key layers of the genome in various cancers. TSPEAR-AS2 was highlighted to be a candidate lncRNA potentially involved in gastric cancer (GC) progression. However, the clinical significance and mecha
Externí odkaz:
https://doaj.org/article/4d4f63ac3a38438ba23cf93f5b5cb904
Autor:
Xiaojing Cheng, Zhixue Zheng, Zhaode Bu, Xiaojiang Wu, Lianhai Zhang, Xiaofang Xing, Xiaohong Wang, Ying Hu, Hong Du, Lin Li, Shen Li, Rouli Zhou, Xian-Zi Wen, Jia-Fu Ji
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0121559 (2015)
Lysosome-associated transmembrane protein 4β-35 (LAPTM4B-35), a member of the mammalian 4-tetratransmembrane spanning protein superfamily, has been reported to be overexpressed in several cancers. However the expression of LAPTM4B-35 and its role in
Externí odkaz:
https://doaj.org/article/4dd8055d17074a04941f8fea4ddc9515
Publikováno v:
Annals of Surgical Oncology. 28:1407-1416
Immunogenic chemotherapy promotes antitumor immune response in the tumor microenvironment (TME). In gastric cancer, the effect of a preexisting T-cell–inflamed TME on the efficacy of adjuvant chemotherapy (ACT) is unclear. The purpose of the presen
Autor:
Xiangji Ying, Kelong Fan, Huirong Ding, Meng Zhou, Jiafu Ji, Ying Hu, Ziyu Li, Xiyun Yan, Hong Du, Xiaojing Cheng, Xiaofang Xing, Lin Wang, Ting Guo, Andrew James Sanders, Xian-Zi Wen, Wenguo Jiang
Publikováno v:
Cell Death and Disease, Vol 11, Iss 2, Pp 1-13 (2020)
Cell Death & Disease
Cell Death & Disease
H-ferritin (HFn) nanocarrier is emerging as a promising theranostic platform for tumor diagnosis and therapy, which can specifically target tumor cells via binding transferrin receptor 1 (TfR1). This led us to investigate the therapeutic function of
Publikováno v:
Molecular Cancer, Vol 19, Iss 1, Pp 1-22 (2020)
Molecular Cancer
Molecular Cancer
BackgroundCircular RNAs (circRNAs) are a new class of endogenous non-coding RNAs (ncRNAs) widely expressed in eukaryotic cells. Mounting evidence has highlighted circRNAs as critical regulators of various tumours. More importantly, circRNAs have been
Autor:
Xiaojing Cheng, Fengming Luan, Tao Fu, Xian-Zi Wen, Jiafu Ji, Jing Han, Longtao Huangfu, Hong Du, Chao Gao, Lin Wang, Ting Guo
Publikováno v:
Cancer Management and Research. 11:7877-7891
Purpose Eukaryotic translation initiation factor (EIF) plays a vital role in protein synthesis. EIF3B is a core subunit of the EIF3 family, and is overexpressed in many tumors. EIF3B is associated with an unfavorable prognosis, as well as the genesis
Autor:
Xian-Zi Wen, Jing Han, Jiafu Ji, Han-Chen Huang, Qing-Da Li, Xiaomei Li, Meng-Lin Nie, Hong Du, Ting Guo, Longtao Huangfu, Xiaojing Cheng
Publikováno v:
Cancer Management and Research. 11:5375-5391
Purpose: Emerging evidence has shown that long noncoding RNAs (lncRNAs) participate in oncogenesis and tumor progression. We previously found a novel lncRNA p4516 which was closely associated with prognosis by preliminary study of lncRNA expression p
Publikováno v:
Chinese Journal of Cancer Research
Objective Tumor heterogeneity renders identification of suitable biomarkers of gastric cancer (GC) challenging. Here, we aimed to identify prognostic genes of GC using computational analysis. Methods We first used microarray technology to profile gen
Autor:
Meng Xie, Meng-Lin Nie, Qing-Da Li, Xian-Zi Wen, Hong Du, Xiaohong Wang, Ziyu Li, Haibo Han, Ting Guo, Yan-hua Bai, Ying Hu, Xiaofang Xing, Jiafu Ji, Chen-guang Zhang, Xiaojing Cheng, Yongning Jia
Publikováno v:
Cell Death and Disease, Vol 10, Iss 2, Pp 1-14 (2019)
Cell Death & Disease
Cell Death & Disease
ISL1, a LIM-homeodomain transcription factor, serves as a biomarker of metastasis in multiple tumors. However, the function and underlying mechanisms of ISL1 in gastric cancer (GC) have not been fully elucidated. Here we found that ISL1 was frequentl
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 22, Iss, Pp 1129-1141 (2020)
Molecular Therapy: Nucleic Acids, Vol 22, Iss, Pp 1129-1141 (2020)
Long non-coding RNAs (lncRNAs) are characterized as key layers of the genome in various cancers. TSPEAR-AS2 was highlighted to be a candidate lncRNA potentially involved in gastric cancer (GC) progression. However, the clinical significance and mecha