Zobrazeno 1 - 10
of 776
pro vyhledávání: '"Xian-Zheng Zhang"'
Autor:
Zi-Yi Han, Zhuang-Jiong Fu, Yu-Zhang Wang, Cheng Zhang, Qi-Wen Chen, Jia-Xin An, Xian-Zheng Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The intratumor microbiome imbalance in pancreatic cancer promotes a tolerogenic immune response and triggers immunotherapy resistance. Here we show that Lactobacillus rhamnosus GG probiotics, outfitted with a gallium-polyphenol network (LGG@
Externí odkaz:
https://doaj.org/article/99969d708bdd4640be9615ce14b85c15
Publikováno v:
Advanced Science, Vol 11, Iss 6, Pp n/a-n/a (2024)
Abstract A critical challenge of existing cancer vaccines is to orchestrate the demands of antigen‐enriched furnishment and optimal antigen‐presentation functionality within antigen‐presenting cells (APCs). Here, a complementary immunotherapeut
Externí odkaz:
https://doaj.org/article/23308effb42944cea34e490dba3a4aa0
Autor:
Xinhua Liu, Youteng Qin, Liyun Dong, Ziyi Han, Tianning Liu, Ying Tang, Yun Yu, Jingjie Ye, Juan Tao, Xuan Zeng, Jun Feng, Xian-Zheng Zhang
Publikováno v:
Bioactive Materials, Vol 21, Iss , Pp 253-266 (2023)
Many skin diseases, such as atopic dermatitis (AD), are featured with the dysbiosis of skin microbiota. The clinically recommended options for AD treatments suffer from poor outcomes and high side-effects, leading to severe quality-of-life impairment
Externí odkaz:
https://doaj.org/article/d777e3e54ca541d6af590c0eb43d80be
Autor:
Jian‐Hua Yan, Di‐Wei Zheng, Hui‐Yun Gu, Yun‐Jian Yu, Jin‐Yue Zeng, Qi‐Wen Chen, Ai‐Xi Yu, Xian‐Zheng Zhang
Publikováno v:
Advanced Science, Vol 10, Iss 4, Pp n/a-n/a (2023)
Abstract Systematic administration of antibiotics to treat infections often leads to the rapid evolution and spread of multidrug‐resistant bacteria. Here, an in situ‐formed biotherapeutic gel that controls multidrug‐resistant bacterial infectio
Externí odkaz:
https://doaj.org/article/9b0faeac412044d68aa0c01848060e91
Publikováno v:
Advanced Science, Vol 9, Iss 17, Pp n/a-n/a (2022)
Abstract Cholestatic drug‐induced liver injury (DILI) induced by drugs or other xenobiotics is a severe and even fatal clinical syndrome. Here, living materials of hierarchy‐assembled dual probiotics system are fabricated by sequentially encapsul
Externí odkaz:
https://doaj.org/article/c2038a07c11d4241b0e642ff370988ee
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 940 (2023)
Photodynamic therapy (PDT) is a promising strategy for cancer treatment. However, a poor tissue penetration of activation light and low target specificity seriously hindered the clinical application of PDT. Here, we designed and constructed a size-co
Externí odkaz:
https://doaj.org/article/72744c56321f4dc6ab7ba0d8f5914e8d
Autor:
Di-Wei Zheng, Sheng Hong, Qiu-Ling Zhang, Xue Dong, Pei Pan, Wen-Fang Song, Wen Song, Si-Xue Cheng, Xian-Zheng Zhang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The extracellular matrix (ECM) can influence tumor growth and its response to therapy. Here, the authors develop a fibrinogen and thrombin based artificial ECM that can starve tumours and prevent dissemination of cancer cells.
Externí odkaz:
https://doaj.org/article/5ecac35df00f43fe86be05abd44bbf7e
Autor:
Di-Wei Zheng, Fan Gao, Qian Cheng, Peng Bao, Xue Dong, Jin-Xuan Fan, Wen Song, Xuan Zeng, Si-Xue Cheng, Xian-Zheng Zhang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Immune checkpoint blockade (ICB) immunotherapy efficacy has still limitations. Here, the authors generate a vaccine that integrates CD274 siRNA into the L1 protein of human papillomavirus, which cooperates with ICB by activating innate immunity in br
Externí odkaz:
https://doaj.org/article/a6b06cb0091e4b669efd503940dbedac
Publikováno v:
ACS Central Science, Vol 6, Iss 4, Pp 555-565 (2020)
Externí odkaz:
https://doaj.org/article/577bb6faea5341c294c3bb5f46308140
Publikováno v:
Advanced NanoBiomed Research, Vol 1, Iss 10, Pp n/a-n/a (2021)
Live cells are implicated in diverse biological processes, including nutrient transport and removal of foreign substances. Their intelligent biofunctions with complex mechanisms cannot be replicated at all in man‐made materials despite the signific
Externí odkaz:
https://doaj.org/article/9eff2610c3ef4042a346a26cef54a91c