Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Xian-Zhang Wang"'
Autor:
Le Wen, Xian-Zhang Wang, Yong Qiu, Yue-Peng Zhou, Qing-Yang Zhang, Shuang Cheng, Jin-Yan Sun, Xing-Jun Jiang, Simon Rayner, William J Britt, Jian Chen, Fei Hu, Fang-Cheng Li, Min-Hua Luo, Han Cheng
Publikováno v:
PLoS Pathogens, Vol 19, Iss 4, p e1011316 (2023)
The presence of human cytomegalovirus (HCMV) in glioblastoma (GBM) and improved outcomes of GBM patients receiving therapies targeting the virus have implicated HCMV in GBM progression. However, a unifying mechanism that accounts for the contribution
Externí odkaz:
https://doaj.org/article/f5e4674bd37b4ebb8b6023ef29db6ae1
Autor:
Xian-Zhang Wang, Le Wen, Yue-Peng Zhou, Sheng-Nan Huang, Bo Yang, Shuang Cheng, Wen-Bo Zeng, Meng-Jie Mei, Jin-Yan Sun, Xuan Jiang, Han Cheng, Min-Hua Luo
Publikováno v:
PLoS Pathogens, Vol 19, Iss 2, p e1011166 (2023)
Congenital human cytomegalovirus (HCMV) infection causes severe damage to the fetal brain, and the underlying mechanisms remain elusive. Cytokine signaling is delicately controlled in the fetal central nervous system to ensure proper development. Her
Externí odkaz:
https://doaj.org/article/c1f51dd46253487aa21798b962ca84a2
Autor:
Yue-Peng Zhou, Meng-Jie Mei, Xian-Zhang Wang, Sheng-Nan Huang, Lin Chen, Ming Zhang, Xin-Yan Li, Hai-Bin Qin, Xiao Dong, Shuang Cheng, Le Wen, Bo Yang, Xue-Fang An, Ao-Di He, Bing Zhang, Wen-Bo Zeng, Xiao-Jun Li, Youming Lu, Hong-Chuang Li, Haidong Li, Wei-Guo Zou, Alec J. Redwood, Simon Rayner, Han Cheng, Michael A. McVoy, Qiyi Tang, William J. Britt, Xin Zhou, Xuan Jiang, Min-Hua Luo
Publikováno v:
JCI Insight, Vol 7, Iss 1 (2022)
Congenital cytomegalovirus (cCMV) infection is the leading infectious cause of neurodevelopmental disorders. However, the neuropathogenesis remains largely elusive due to a lack of informative animal models. In this study, we developed a congenital m
Externí odkaz:
https://doaj.org/article/a84c40cfdd2d4bf8aa2063cff7bfd216
Autor:
Sheng-Nan Huang, Yu-Ting Pan, Yue-Peng Zhou, Xian-Zhang Wang, Meng-Jie Mei, Bo Yang, Dong Li, Wen-Bo Zeng, Shuang Cheng, Jin-Yan Sun, Han Cheng, Fei Zhao, Min-Hua Luo
Publikováno v:
Journal of Virology. 97
Congenital CMV (cCMV) infection causes neurological sequelae in newborns. Recent studies of cCMV pathogenesis in animal models reveal ventriculomegaly and cortical atrophy associated with impaired neural progenitor cell (NPC) proliferation and migrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c27d4de29c5074a6cc50983c62302fcb
https://doi.org/10.1128/jvi.00313-23
https://doi.org/10.1128/jvi.00313-23
Autor:
Xue‐Hui Ma, Yong‐Xuan Yao, Xian‐Zhang Wang, Yue‐Peng Zhou, Sheng‐Nan Huang, Dong Li, Meng‐Jie Mei, Jing‐Peng Wu, Yu‐Ting Pan, Shuang Cheng, Xuan Jiang, Jin‐Yan Sun, Wen‐Bo Zeng, Sitang Gong, Han Cheng, Min‐Hua Luo, Bo Yang
Publikováno v:
Journal of medical virologyREFERENCES. 94(11)
During the long coevolution of human cytomegalovirus (HCMV) and humans, the host has formed a defense system of multiple layers to eradicate the invader, and the virus has developed various strategies to evade host surveillance programs. The intrinsi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ab62fbd787d4d376b986cb7fc34569
https://pubmed.ncbi.nlm.nih.gov/35879101
https://pubmed.ncbi.nlm.nih.gov/35879101
Autor:
Bo Yang, YongXuan Yao, Han Cheng, Xian-Zhang Wang, Yue-peng Zhou, Sheng-Nan Huang, Xuehui Ma, Hong Yang, Jinpeng Wu, Xuan Jiang, Shuang Cheng, Jin-Yan Sun, Wen-Bo Zeng, Jason Chen, Fu-Kun Zhang, Hong-Jie Shen, Jian-Yang Gu, Michael A. McVoy, William J. Britt, Sitang Gong, Min-Hua Luo
Publikováno v:
J Virol
Human cytomegalovirus (HCMV) has a large (∼235 kb) genome with more than 200 predicted open reading frames that exploits numerous cellular factors to facilitate its replication. A key feature of HCMV-infected cells is the emergence of a distinctive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1425d3d3390c944f77c86fe34fe833df
https://europepmc.org/articles/PMC8906412/
https://europepmc.org/articles/PMC8906412/
Autor:
Dong Li, Sitang Gong, Zhen-Li Huang, Hong Yang, Xian-Zhang Wang, Cong-Jian Zhao, Yongxuan Yao, Jin-Yan Sun, Jin-Hyun Ahn, Hui Wu, Bo Yang, Wen-Bo Zeng, Michael A. McVoy, Sheng-Nan Huang, Xue-Hui Ma, Xuan Jiang, William J. Britt, Min-Hua Luo, Shuang Cheng
Publikováno v:
J Virol
We previously reported that human cytomegalovirus (HCMV) utilizes the cellular protein WD repeat-containing protein 5 (WDR5) to facilitate capsid nuclear egress. Here, we further show that HCMV infection results in WDR5 localization in a juxtanuclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa91502320ca340dab66b7094d211b9
https://doi.org/10.1128/jvi.02101-20
https://doi.org/10.1128/jvi.02101-20
Publikováno v:
Industrial & Engineering Chemistry Research; 12/1/2021, Vol. 60 Issue 47, p16951-16960, 10p
Autor:
Yanyi Wang, Yongxuan Yao, Michael A. McVoy, Jin-Yan Sun, Yun Miao, Qiyi Tang, Xi-Juan Liu, Wei Wang, Xian-Zhang Wang, Xuan Jiang, William J. Britt, Hong Yang, Simon Rayner, Bo Yang, Zhen-Li Huang, Fei Zhao, Min-Hua Luo
Publikováno v:
Journal of Virology. 92
WD repeat-containing protein 5 (WDR5) is essential for assembling the VISA-associated complex to induce a type I interferon antiviral response to Sendai virus infection. However, the roles of WDR5 in DNA virus infections are not well described. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f398b4fc60152e7f9789b2cef0f14d2
https://doi.org/10.1128/jvi.00207-18
https://doi.org/10.1128/jvi.00207-18
Autor:
Min-Hua Luo, Han-Qing Ye, Christina Paulus, Huimin Xia, Wei Wang, Xi-Juan Liu, Michael Nevels, Bo Yang, Man Jiang, William J. Britt, Cong-Cong Wu, Thomas Harwardt, Xian-Zhang Wang, Xiao-Jun Li, Xuan Jiang
The mechanisms underlying neurodevelopmental damage caused by virus infections remain poorly defined. Congenital human cytomegalovirus (HCMV) infection is the leading cause of fetal brain development disorders. Previous work has linked HCMV to pertur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9be876c6383c66e8501964681ad65b9e