Výsledky vyhledávání - "Xian-Long Fang"

Akademický článek

Preliminary efficacy and safety of YSCH-01 in patients with advanced solid tumors: an investigator-initiated trial

Autor: Rong Zhang, Min Liu, Xiaoxia Li, Feng Liu, Yanqiu Liu, Wenting Zhong, Hongwei Liu, Yandong He, Xuhong Huang, Junjia Tao, Yuanzhou Shan, Hafiz Khuram Raza, Xue-ping Cao, Yuan-yuan Yang, Ruimei Li, Xian-long Fang, Kang-jian Zhang

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 5 (2024)

Objective To evaluate the safety and preliminary efficacy of YSCH-01 (Recombinant L-IFN adenovirus) in subjects with advanced solid tumors.Methods In this single-center, open-label, investigator-initiated trial of YSCH-01, 14 patients with advanced s

Externí odkaz: https://doaj.org/article/fb45b65080ba48b69a0ddfc121103402

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Supplementary Information from A Potent In Vivo Antitumor Efficacy of Novel Recombinant Type I Interferon

Supplementary methods, tables, figures and legends to figures Supplementary Figure 1. The structure of AB loops for sIFN-I and IFNα-2b and comparison on the sequences for sIFN-I and IFNα-21. Supplementary Figure 2. Quantification of phosphorylaiton

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d7d534bf96dd0984a42cde1954afaf
https://doi.org/10.1158/1078-0432.22466456.v1

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Data from A Potent In Vivo Antitumor Efficacy of Novel Recombinant Type I Interferon

Purpose: Antiproliferative, antiviral, and immunomodulatory activities of endogenous type I IFNs (IFN1) prompt the design of recombinant IFN1 for therapeutic purposes. However, most of the designed IFNs exhibited suboptimal therapeutic efficacies aga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b3b4d772358fb107d6a9cddd1ecf806
https://doi.org/10.1158/1078-0432.c.6526319

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