Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Xian-Ling Yang"'
Publikováno v:
ACS macro letters. 8(6)
A trackable water-soluble prodrug conjugate possessing high contents of chlorambucil (Cb) and triphenylphosphonium cation (TPP) was designed and developed after TPP modification on the “branch” of amphipathic prodrugs based on convenient synthesi
Publikováno v:
ACS Applied Bio Materials. 3:7382-7387
A facile strategy to construct dual-drug delivery nanoparticles (TL-CPT NPs), which possessed higher loading content of CPT and TPP-LND. Notably, TL-CPT NPs showed promising ultrarapid pH/GSH respo...
Autor:
Meng-Qian Zhang, Meng-Yang Li, Yan-Hong Liu, Jun Li, Xiao-Qi Yu, Na Wang, Xian-Ling Yang, Yun-Jie Wei, Zu-E Hu, Wan-Xia Wu
Publikováno v:
ACS Applied Materials & Interfaces. 12:32432-32445
To maximize the utilization and response to the high oxidative stress environment of tumor sites while avoiding the dilemma of enhancing reactive oxygen species (ROS) response in a single way, mitochondrial targeting combined with fluorescent self-re
Publikováno v:
Pakistan Veterinary Journal, Vol 32, Iss 4, Pp 601-604 (2012)
Alanine aminotransferase (ALT), aspartate aminotransferase (AST), γ-glutamyl- transferase (GGT), and alkaline phosphatase (ALP) are important catabolic enzymes, which play an important role in liver function of animals. The activities of these enzym
Externí odkaz:
https://doaj.org/article/7c5db71442ef4678978e2c0ca995205e
Publikováno v:
RSC Advances. 9:6003-6010
Although functional aliphatic polycarbonates (APCs) have attracted prominent research interest as stimuli-responsive biomaterials, the majority of functional APCs are fabricated by detrimental organometallic catalysts or organo-catalysts. Herein, a f
Autor:
Zu-E Hu, Na Wang, Xian-Ling Yang, Jun Li, Xiu Xing, Yan-Hong Liu, Bo Gu, Wan-Xia Wu, Xiao-Qi Yu
Publikováno v:
Biomaterials Science. 7:3277-3286
Dual stimuli-responsive camptothecin polymeric prodrugs (CPT Prodrugs) with grafted structures were designed via chemoenzymatic methods and combined with doxorubicin (DOX) for synergistic drug delivery to improve anticancer efficiency. The CPT Prodru
Publikováno v:
Journal of materials chemistry. B. 6(43)
A series of amphiphilic graft copolymers, poly(N-propargyldiethanolamine 4,4'-dithiodibutyionate)-graft-monomethoxy poly(ethylene glycol) (PPD-g-mPEG), were designed via a chemoenzymatic method for pH and reduced glutathione (GSH) dual-responsive dru
Publikováno v:
Polymer Chemistry. 8:5982-5987
A series of mitochondria-targeting amphipathic prodrugs were developed and subsequently the relationship of different locations of TPP modification and molecular weights of mPEG for selective imaging and therapeutic targeting were tested. The aqueous
Publikováno v:
Materials scienceengineering. C, Materials for biological applications. 108
In the field of drug delivery, the controlled release of drugs is continuously one of the highly prioritized research domains. Stimuli-responsive polymers are being investigated as drug delivery vehicles that modulate pharmaceutical effect via tumor
Publikováno v:
RSC Advances. 6:11870-11879
A series of novel oxidation-responsive amphiphilic diblock copolymers with β-thioether ester groups were synthesized via the one-step lipase-catalyzed polycondensation of methyl 3-((2-hydroxyethyl)thio)propanoate (MHETP) with monomethoxy poly(ethyle