Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Xian-Chun Yan"'
Autor:
Zi-Yan Yang, Xian-Chun Yan, Jia-Yu-Lin Zhang, Liang Liang, Chun-Chen Gao, Pei-Ran Zhang, Yuan Liu, Jia-Xing Sun, Bai Ruan, Juan-Li Duan, Ruo-Nan Wang, Xing-Xing Feng, Bo Che, Tian Xiao, Hua Han
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 20 (2023)
Human cancers induce a chaotic, dysfunctional vasculature that promotes tumor growth and blunts most current therapies; however, the mechanisms underlying the induction of a dysfunctional vasculature have been unclear. Here, we show that split end (S
Externí odkaz:
https://doaj.org/article/bd6ace602e4845dc99347c79490dd45e
Autor:
Jia-Xing Sun, Guo-Rui Dou, Zi-Yan Yang, Liang Liang, Juan-Li Duan, Bai Ruan, Man-Hong Li, Tian-Fang Chang, Xin-Yuan Xu, Juan-Juan Chen, Yu-Sheng Wang, Xian-Chun Yan, Hua Han
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 25, Iss , Pp 554-566 (2021)
After angiogenesis-activated embryonic and early postnatal vascularization, endothelial cells (ECs) in most tissues enter a quiescent state necessary for proper tissue perfusion and EC functions. Notch signaling is essential for maintaining EC quiesc
Externí odkaz:
https://doaj.org/article/6b355598f6fc466e98e22b4d43c3b38d
Autor:
Fang Gao, Yu-Fei Zhang, Zheng-Ping Zhang, Luo-An Fu, Xiu-Li Cao, Yi-Zhe Zhang, Chen-Jun Guo, Xian-Chun Yan, Qin-Chuan Yang, Yi-Yang Hu, Xiang-Hui Zhao, Ya-Zhou Wang, Sheng-Xi Wu, Gong Ju, Min-Hua Zheng, Hua Han
Publikováno v:
Stem Cell Reports, Vol 8, Iss 4, Pp 1032-1045 (2017)
Summary: Notch signaling is critically involved in neural development, but the downstream effectors remain incompletely understood. In this study, we cultured neurospheres from Nestin-Cre-mediated conditional Rbp-j knockout (Rbp-j cKO) and control em
Externí odkaz:
https://doaj.org/article/71dd106965c14f438f70175d16c22a66
Autor:
Xian‐Chun Yan, Jing Cao, Liang Liang, Li Wang, Fang Gao, Zi‐Yan Yang, Juan‐Li Duan, Tian‐Fang Chang, San‐Ming Deng, Yuan Liu, Guo‐Rui Dou, Jian Zhang, Qi‐Jun Zheng, Ping Zhang, Hua Han
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 2 (2016)
BackgroundEndothelial cells (ECs) form blood vessels through angiogenesis that is regulated by coordination of vascular endothelial growth factor (VEGF), Notch, transforming growth factor β, and other signals, but the detailed molecular mechanisms r
Externí odkaz:
https://doaj.org/article/eef58ee14aa048468431e50968e09608
Autor:
Manhong Li, Guo-Rui Dou, Juan-Juan Chen, Bai Ruan, Jia-Xing Sun, Liang Liang, Hua Han, Xin-Yuan Xu, Zi-Yan Yang, Tian-Fang Chang, Juan-Li Duan, Xian-Chun Yan, Yusheng Wang
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 25, Iss, Pp 554-566 (2021)
Molecular Therapy: Nucleic Acids, Vol 25, Iss, Pp 554-566 (2021)
After angiogenesis-activated embryonic and early postnatal vascularization, endothelial cells (ECs) in most tissues enter a quiescent state necessary for proper tissue perfusion and EC functions. Notch signaling is essential for maintaining EC quiesc
Publikováno v:
Journal of Biological Education. :1-11
With the better understanding of human genome and genetic contributions to human complex diseases, more and more clinical genetic tests have been developed for the prevention, diagnosis, and treatm...
Autor:
Xian-Chun Yan, Hua Han, Min-Hua Zheng, Xiu-Li Cao, Yu-Fei Zhang, Jian Zhang, Xinxin Zhang, Zi-Yan Yang, Jing Cao, Xiao-Wei Liu, Liang Liang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-14 (2020)
Background Malformation of blood vessels represents a hallmark of cancers, but the role and regulation of vascular mural cells (vMCs), including vascular smooth muscle cells (vSMCs) and pericytes, in tumors has not been fully understood. SM22α has b
Publikováno v:
AoB PLANTS. 14
The evolution of persistent calyces may be an adaptation to ensure reproductive success of certain flowering plants. However, experimental evidence of the functions of persistent calyces during flowering and seed development remains scarce. We explor
Publikováno v:
AoB PLANTS. 13
Pollen and nectar are the primary rewards offered by flowers to pollinators. In floral visitors of some plant species, pollen thieves and nectar robbers cause the reduction in pollen grain number and nectar volume, respectively. However, it remains u
Publikováno v:
AoB Plants
Pollen and nectar are the primary rewards offered by flowers to pollinators. In floral visitors of some plant species, pollen thieves and nectar robbers cause the reduction in pollen grain number and nectar volume, respectively. However, it remains u