Hepatic and extrahepatic metabolic modulation in hbv-related decompensated cirrhosis and acute-on-chronic liver failure.

Autor: Li ZW; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health Key Laboratory of Organ Transplantation, Hangzhou, China., Tu S; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Yu X; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Wang YJ; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Department of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Gong K; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Department of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Yang DX; Department of Toxicology of School of Public Health, School of Medicine, Zhejiang University, Hangzhou, China., Yao JJ; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Department of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Ren HT; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Department of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Wu DX; Department of Infectious Diseases, The First Affiliated Hospital, Nanchang University, Nanchang, China., Zhang ZH; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Su XL; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Wang Y; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Pan ZY; Cellular Biology Platform, Jinan Microecological Biomedicine Shandong Laboratory, Jinan, Shandong, China., Zhao RH; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Department of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Sheng JF; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Department of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Qiu YQ; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Department of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Shi Y; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Department of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Sun ZY; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

Publikováno v: Virulence [Virulence] 2024 Dec; Vol. 15 (1), pp. 2404953. Date of Electronic Publication: 2024 Sep 23.

Machine learning-assisted amidase-catalytic enantioselectivity prediction and rational design of variants for improving enantioselectivity.

Autor: Li ZL; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China., Pei S; Key Laboratory of Theoretical and Computational Photochemistry of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing, China., Chen Z; Key Laboratory of Theoretical and Computational Photochemistry of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing, China., Huang TY; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China., Wang XD; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China., Shen L; Key Laboratory of Theoretical and Computational Photochemistry of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing, China. lshen@bnu.edu.cn.; Yantai-Jingshi Institute of Material Genome Engineering, Yantai, China. lshen@bnu.edu.cn., Chen X; Key Laboratory of Theoretical and Computational Photochemistry of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing, China. xuebochen@bnu.edu.cn.; Yantai-Jingshi Institute of Material Genome Engineering, Yantai, China. xuebochen@bnu.edu.cn.; Shandong Laboratory of Yantai Advanced Materials and Green Manufacturing, Yantai, China. xuebochen@bnu.edu.cn., Wang QQ; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China., Wang DX; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China., Ao YF; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China. aoyufe@iccas.ac.cn.; University of Chinese Academy of Sciences, Beijing, China. aoyufe@iccas.ac.cn.

Publikováno v: Nature communications [Nat Commun] 2024 Oct 10; Vol. 15 (1), pp. 8778. Date of Electronic Publication: 2024 Oct 10.

Spontaneous Transition between Multiple Conductance States and Rectifying Behaviors in an Artificial Single-Molecule Funnel.

Autor: Lin JF; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Wang XD; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China., Ao YF; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Wang QQ; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Wang DX; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Oct 01; Vol. 63 (40), pp. e202411702. Date of Electronic Publication: 2024 Aug 25.

Precirrhotic Primary Biliary Cholangitis with Portal Hypertension: Bile Duct Injury Correlate.

Autor: Hu YF; Department of Infectious Disease and Liver Disease, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, Nanjing, China., Li SX; Department of Infectious Disease and Liver Disease, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, Nanjing, China., Liu HL; Department of Second Clinical Medical College, Southeast University School of Medicine, Nanjing, China., Du ZX; Department of Infectious Disease and Liver Disease, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, Nanjing, China., Wang SS; Department of School of Public Health, Nanjing Medical University, Nanjing, China., Chen MY; Department of Infectious Disease and Liver Disease, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, Nanjing, China., Wang L; Department of Infectious Disease and Liver Disease, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, Nanjing, China., Xiong QF; Department of Infectious Disease and Liver Disease, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, Nanjing, China., Zhong YD; Department of Infectious Disease and Liver Disease, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, Nanjing, China., Liu DX; Department of Pathology, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, Nanjing, China., Yang YF; Department of Infectious Disease and Liver Disease, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, Nanjing, China.

Publikováno v: Gut and liver [Gut Liver] 2024 Sep 15; Vol. 18 (5), pp. 867-876. Date of Electronic Publication: 2024 Apr 16.

Preparation, pharmacokinetics and anti-obesity effects on dogs of nuciferine liposomes.

Autor: Lu J; Department of Pet Science and Technology, Jiangsu Agri-Animal Husbandry Vocational College, Taizhou, China., Xu YT; Department of Pet Science and Technology, Jiangsu Agri-Animal Husbandry Vocational College, Taizhou, China., Qian XL; Department of Canine Disease Outpatient, Wuxi Paideshi Pet Hospital, Wuxi, China., Zhu DX; Department of Animal Medicine, Jiangsu Agri-Animal Husbandry Vocational College, Taizhou, China., Lu JY; Department of Pet Science and Technology, Jiangsu Agri-Animal Husbandry Vocational College, Taizhou, China., Ma H; Department of Pet Science and Technology, Jiangsu Agri-Animal Husbandry Vocational College, Taizhou, China., Liu J; Department of Pet Science and Technology, Jiangsu Agri-Animal Husbandry Vocational College, Taizhou, China.

Publikováno v: Veterinary medicine and science [Vet Med Sci] 2024 Sep; Vol. 10 (5), pp. e70017.