Zobrazeno 1 - 10
of 230
pro vyhledávání: '"Xian Chang Li"'
Autor:
Mingli Fang, Ao Zhang, Yong Du, Wenting Lu, Junying Wang, Laurie J. Minze, Timothy C. Cox, Xian Chang Li, Junji Xing, Zhiqiang Zhang
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-20 (2022)
Abstract Background Infections by viruses including severe acute respiratory syndrome coronavirus 2 could cause organ inflammations such as myocarditis, pneumonia and encephalitis. Innate immunity to viral nucleic acids mediates antiviral immunity as
Externí odkaz:
https://doaj.org/article/82994d7153f24275860532824be4a797
Autor:
Junji Xing, Ao Zhang, Yong Du, Mingli Fang, Laurie J. Minze, Yong-Jun Liu, Xian Chang Li, Zhiqiang Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Innate immune cells play critical roles patrolling for and detecting viral infection by expression of a range of nucleic acid sensors. Here the authors implicate PARP9 in the detection of viral RNA and the induction of the IFN pathway via PI3K/AKT3.
Externí odkaz:
https://doaj.org/article/a71c12caa26f44d78217562e8216d63b
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Proteins of the TRIM family have regulatory functions in immune signaling, often via ubiquitination of target proteins. Here, the authors show that TRIM29 is induced upon infection with DNA viruses, resulting in degradation of STING, decreased interf
Externí odkaz:
https://doaj.org/article/d562b06923eb4f768531d624223a11f4
Autor:
Xiaojun Xia, Junhua Mai, Rong Xu, Jorge Enrique Tovar Perez, Maria L. Guevara, Qi Shen, Chaofeng Mu, Hui-Ying Tung, David B. Corry, Scott E. Evans, Xuewu Liu, Mauro Ferrari, Zhiqiang Zhang, Xian Chang Li, Rong-fu Wang, Haifa Shen
Publikováno v:
Cell Reports, Vol 11, Iss 6, Pp 957-966 (2015)
Micro- and nanometer-size particles have become popular candidates for cancer vaccine adjuvants. However, the mechanism by which such particles enhance immune responses remains unclear. Here, we report a porous silicon microparticle (PSM)-based cance
Externí odkaz:
https://doaj.org/article/7bc414590aaf474d8d8d75a29ce4edeb
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77322 (2013)
The peripheral Foxp3(+) Treg pool consists of naturally arising Treg (nTreg) and adaptive Treg cells (iTreg). It is well known that naive CD4(+) T cells can be readily converted to Foxp3(+) iTreg in vitro, and memory CD4(+) T cells are resistant to c
Externí odkaz:
https://doaj.org/article/f9cc2465bd374f65bd1ddcb51067534b
Autor:
Stephen Paul Cobbold, Xian Chang Li
Publikováno v:
Frontiers in Immunology, Vol 3 (2012)
Externí odkaz:
https://doaj.org/article/0d7283600d0c4c8ea6ab4b699904b3d1
Autor:
Wenhao Chen, Gangcheng Kong, Mou Wen, Xiang Xiao, Nianguo Dong, Guangchuan Wang, Yixuan Wang, Rafik M. Ghobrial, Xian Chang Li
Publikováno v:
Am J Transplant
T cells must be activated and become effectors first before executing allograft rejection, a process that is regulated by diverse signals and transcription factors. In the present study, we studied the basic leucine zipper ATF-like transcription fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb08516f0f9e4b41f674a5ac8d767a2
https://doi.org/10.1111/ajt.16861
https://doi.org/10.1111/ajt.16861
Autor:
Stephanie G. Yi, Dawei Zou, Yixuan Wang, Wenhao Chen, Xian Chang Li, A. Osama Gaber, Guohua Wang, Nancy M. Gonzalez
Publikováno v:
The Journal of Heart and Lung Transplantation. 40:1122-1132
BACKGOUND B cells contribute to chronic transplant rejection by producing donor-specific antibodies and promoting T cell response , but how these processes are regulated at the transcriptional level remains unclear. Herein, we investigate the role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c1ef07476fa1ba4b0009817d4bc5947
https://doi.org/10.1016/j.healun.2021.06.008
https://doi.org/10.1016/j.healun.2021.06.008
Autor:
Gabriel M. Danovitch, Ronald W. Busuttil, Ashish Saharia, Keri E. Lunsford, Michael P. Harlander-Locke, Stephanie G. Yi, Mark J. Hobeika, Vatche G. Agopian, A. Osama Gaber, R. Mark Ghobrial, Ali Zarrinpar, Xian Chang Li, Richard J. Knight, Jeffrey L. Veale, Douglas G. Farmer, Edward A. Graviss, H. Albin Gritsch, Hemangshu Podder, Duc T. Nguyen, Fady M. Kaldas, Constance M. Mobley
Publikováno v:
Transplantation. 104:1591-1603
Background Combined liver-kidney transplantation (CLKT) improves survival for liver transplant recipients with renal dysfunction; however, the tenuous perioperative hemodynamic and metabolic milieu in high-acuity CLKT recipients increases delayed gra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c26f819391a9644a630ce786f35f3aa
https://doi.org/10.1097/tp.0000000000003040
https://doi.org/10.1097/tp.0000000000003040