Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Xialin Zhu"'
Recent advances in targeted gene silencing and cancer therapy by nanoparticle-based delivery systems
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 157, Iss , Pp 114065- (2023)
Nanomedicine has emerged as a promising platform for disease treatment and much progress has been achieved in the clinical translation for cancer treatment. Several types of nanomedicines have been approved for therapeutic application. However, many
Externí odkaz:
https://doaj.org/article/5f709c182cf940e0813258e03411326d
Autor:
Xialin Zhu, Yun Chen, Xu Xu, Xiaoju Xu, Yin Lu, Xi Huang, Jinpei Zhou, Lihong Hu, Jiaying Wang, Xu Shen
Publikováno v:
EBioMedicine, Vol 61, Iss , Pp 103061- (2020)
Background: Diabetic peripheral neuropathy (DPN) is a common complication of diabetes severely afflicting the patients, while there is yet no effective medication against this disease. As Kv2.1 channel functions potently in regulating neurological di
Externí odkaz:
https://doaj.org/article/17f1936de0e346c692387c14140d8939
Autor:
Xiaoju Xu, Xu Xu, Yanping Hao, Xialin Zhu, Jian Lu, Xingnan Ouyang, Yin Lu, Xi Huang, Yang Li, Jiaying Wang, Xu Shen
Publikováno v:
iScience, Vol 23, Iss 10, Pp 101617- (2020)
Summary: Diabetic peripheral neuropathy (DPN) is a common diabetic complication and has yet no efficient medication. Here, we report that antispasmodic drug drofenine (Dfe) blocks Kv2.1 and ameliorates DPN-like pathology in diabetic mice. The underly
Externí odkaz:
https://doaj.org/article/9d835a50cf9941f3a04af23139ae18a3
Autor:
Weiqiang Lu, Xialin Zhu, Xu Shen, Chuzhao Zhang, Jiaying Wang, Jianlu Lv, Xingwu Jiang, Zongxiang Tang, Yin Lu, Jian Lu
Publikováno v:
Aging Cell
Alzheimer's disease (AD) is a progressively neurodegenerative disease characterized by cognitive deficits and alteration of personality and behavior. As yet, there is no efficient treatment for AD. 5HT2A receptor (5HT2AR) is a subtype of 5HT2 recepto
Autor:
Xu Shen, Jinpei Zhou, Jiaying Wang, Xi Huang, Wenhu Duan, Yin Lu, Xialin Zhu, Juanzhen Yang, Jiawen Xu, Xiaoju Xu, Jianlu Lv, Zhengyu Wang, Wei Wang, Xu Xu, Ada Admin
Diabetic peripheral neuropathy (DPN) is a long-term complication of diabetes with a complicated pathogenesis. AMP-activated protein kinase (AMPK) senses oxidative stress and mitochondrial function playing a central role in the regulation of DPN. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0c39d541d0e547ca945b78bf7870998
https://doi.org/10.2337/figshare.12583115
https://doi.org/10.2337/figshare.12583115
Autor:
Jinpei Zhou, Jiaying Wang, Xu Shen, Jianlu Lv, Jian Lu, Xi Huang, Xiaoju Xu, Xialin Zhu, Qiuying Yan, Xiaofan Shi, Wenhu Duan, Wei Wang, Zhengyu Wang
Publikováno v:
Brain, behavior, and immunity. 90
Alzheimer's disease (AD) is a progressively neurodegenerative disease with typical hallmarks of amyloid β (Aβ) plaque accumulation, neurofibrillary tangle (NFT) formation and neuronal death extension. In AD brain, activated microglia phagocytose A
Autor:
Xiaoju Xu, Zhengyu Wang, Xu Shen, Yin Lu, Xu Xu, Jiawen Xu, Xi Huang, Xialin Zhu, Jinpei Zhou, Wei Wang, Jiaying Wang, Jianlu Lv, Wenhu Duan, Juanzhen Yang
Publikováno v:
Diabetes. 69(9)
Diabetic peripheral neuropathy (DPN) is a long-term complication of diabetes with a complicated pathogenesis. AMP-activated protein kinase (AMPK) senses oxidative stress, and mitochondrial function plays a central role in the regulation of DPN. Here,
Autor:
Yun Chen, Xi Huang, Xiaoju Xu, Xu Xu, Yin Lu, Lihong Hu, Jinpei Zhou, Xu Shen, Xialin Zhu, Jiaying Wang
Publikováno v:
EBioMedicine, Vol 61, Iss, Pp 103061-(2020)
EBioMedicine
EBioMedicine
Background Diabetic peripheral neuropathy (DPN) is a common complication of diabetes severely afflicting the patients, while there is yet no effective medication against this disease. As Kv2.1 channel functions potently in regulating neurological dis