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Akademický článek

714 Selective expansion of antigen-specific CD8 T cells with engineered antigen presenting exosome

Autor: Tomoyoshi Yamano, Xiabing Lyu, Rikinari Hanayama

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)

Externí odkaz: https://doaj.org/article/bab29c2f9c914b6192734f3e761ee9f4

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Preventing SARS-CoV-2 Infection Using Anti-spike Nanobody-IFN-β Conjugated Exosomes

Autor: Xiabing Lyu, Shota Imai, Tomoyoshi Yamano, Rikinari Hanayama

Publikováno v: Pharmaceutical Research. 40:927-935

To inhibit the transmission of SARS-CoV-2, we developed engineered exosomes that were conjugated with anti-spike nanobodies and type I interferon β (IFN-β). We evaluated the efficacy and potency of nanobody-IFN-β conjugated exosomes to treatment o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc9791fd25a0e7a6e7bdc1a8a227e1b
https://doi.org/10.1007/s11095-022-03400-0

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714 Selective expansion of antigen-specific CD8 T cells with engineered antigen presenting exosome

Autor: Xiabing Lyu, Tomoyoshi Yamano, Rikinari Hanayama

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)

BackgroundExosomes are vesicular granules of about 100 nm and are secreted by many types of cells. Exosomes contain various proteins, lipids, and RNAs that are transported to target cells which induce functional and physiological changes. Exosomes ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be2f363b04ee1314f8ddc6985ea1e5d4
https://doaj.org/article/bab29c2f9c914b6192734f3e761ee9f4

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