Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Xia‐lian Zhu"'
Publikováno v:
Pharmaceutical Biology, Vol 57, Iss 1, Pp 169-175 (2019)
Context: Ursolic acid (UA; 3β-hydroxy-urs-12-en-28-oic acid), one of the pentacyclic triterpenoids found in various plants and herbs, possesses some beneficial effects under pathological conditions, including combating hepatic fibrosis. Objective: T
Externí odkaz:
https://doaj.org/article/8e1c8b61f4474d0bb4af176ad32bb0a4
Autor:
Jian‐hua Zhou, Xia‐lian Zhu, Ming‐yong Li, You‐Wen Luo, Zhi‐Min Yang, Li Wang, Tao Tong, Song‐lin Qin, Bo‐long Liu, Bing‐hai Chen, Wei Hu
Publikováno v:
AndrologiaREFERENCES. 54(10)
Adrenomedullin (ADM) has beneficial effects on Leydig cells under pathological conditions, including lipopolysaccharide (LPS)-induced orchitis. Our previous studies demonstrated that ADM exerts a restorative effect on steroidogenesis in LPS-treated p
Autor:
You-wen Luo, Xia-lian Zhu, Ming-yong Li, Jian-hua Zhou, Zhi-min Yang, Tao Tong, Bing-hai Chen, Song-lin Qin, Bo-long Liu, Wei Hu
To investigate whether adrenomedullin (ADM) rescues the steroidogenic functions of Leydig cells by suppressing transforming growth factor-β1 (TGF-β1) via the Hippo signaling. Primary Leydig cells were treated with lipopolysaccharide (LPS), an adeno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74c76abe0a7a8e53daee7a79073a8a20
https://doi.org/10.21203/rs.3.rs-1468990/v1
https://doi.org/10.21203/rs.3.rs-1468990/v1
Autor:
Wei Hu, Bo Qiu, Wei Wang, Bo-long Liu, Yong Gao, Lei Shi, Xia-lian Zhu, Pang-hu Zhou, Bing-hai Chen, Song-lin Qin, Ming-yong Li, Bi-xia Zhao
Publikováno v:
Cell Death and Disease, Vol 10, Iss 7, Pp 1-14 (2019)
Cell Death & Disease
Cell Death & Disease
Adrenomedullin (ADM) exerts anti-oxidant, anti-inflammatory and anti-apoptotic effects in Leydig cells. However, the role and mechanism of ADM in the pyroptosis of Leydig cells are poorly understood. This study first showed the protective effects of
Publikováno v:
Pharmaceutical Biology
Pharmaceutical Biology, Vol 57, Iss 1, Pp 169-175 (2019)
Pharmaceutical Biology, Vol 57, Iss 1, Pp 169-175 (2019)
Context: Ursolic acid (UA; 3β-hydroxy-urs-12-en-28-oic acid), one of the pentacyclic triterpenoids found in various plants and herbs, possesses some beneficial effects under pathological conditions, including combating hepatic fibrosis. Objective: T
Autor:
Wei Wang, Bo-long Liu, Wei Hu, Song-lin Qin, Ran Kang, Chang-geng Xu, Ming-yong Li, Xia-lian Zhu, Bing-hai Chen
Publikováno v:
SSRN Electronic Journal.
Backgroud: Lipopolysaccharide (LPS) exposure can induce Leydig cell dysfunction. This study aims to investigate whether adrenomedullin (ADM) rescues the steroidogenic functions of Leydig cells by suppressing TGF-β1 via PI3K/Akt/ GSK-3β/β-catenin s