Zobrazeno 1 - 10
of 164
pro vyhledávání: '"XiYong Yu"'
Autor:
Xiaoling Guan, Xiaowei Xu, Yiwen Tao, Xiaohua Deng, Linlong He, Zhongxiao Lin, Jishuo Chang, Jionghua Huang, Dazhi Zhou, Xiyong Yu, Minyan Wei, Lingmin Zhang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Epigenetic regulation has emerged as a promising therapeutic strategy for lung cancer treatment, which can facilitate the antitumor responses by modulating epigenetic dysregulation of target proteins in lung cancer. The proteolysis-targeting
Externí odkaz:
https://doaj.org/article/844e77478f364ceea0fb44ed6bbef605
Autor:
Xueping Lei, Zhan Li, Manting Huang, Lijuan Huang, Yong Huang, Sha Lv, Weisong Zhang, Zhuowen Chen, Yuanyu Ke, Songpei Li, Jingfei Chen, Xiangyu Yang, Qiudi Deng, Junshan Liu, Xiyong Yu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background Tumor angiogenesis inhibitors have been applied for non-small cell lung cancer (NSCLC) therapy. However, the drug resistance hinders their further development. Intercellular crosstalk between lung cancer cells and vascular cells w
Externí odkaz:
https://doaj.org/article/03ad17795c724933b0c38838bd0628ba
Autor:
Aiping Qin, Xiao-juan Wang, Jijun Fu, Ao Shen, Xiaotao Huang, Zhida Chen, Huiting Wu, Yu Jiang, Qian Wang, Fei Chen, Andy Peng Xiang, Xiyong Yu
Publikováno v:
Molecular Biomedicine, Vol 4, Iss 1, Pp 1-19 (2023)
Abstract Immunocompromised individuals are particularly vulnerable to viral infections and reactivation, especially endogenous herpes viruses such as Epstein-Barr virus (EBV), a member of oncogenic gamma-herpesviruses, which are commonly linked to pn
Externí odkaz:
https://doaj.org/article/55ab8c6163614540ae28950483bd4783
Autor:
Yi Zhou, Yingling Miao, Qiudi Huang, Wenwen Shi, Jiacui Xie, Jiachang Lin, Pei Huang, Chengfeng Yue, Yuan Qin, Xiyong Yu, He Wang, Linghao Qin, Jianhai Chen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 7, Pp 3153-3167 (2023)
Metastasis and resistance are main causes to affect the outcome of the current anticancer therapies. Heat shock protein 90 (Hsp90) as an ATP-dependent molecular chaperone takes important role in the tumor metastasis and resistance. Targeting Hsp90 an
Externí odkaz:
https://doaj.org/article/8770009d2fd3463b8f66fe77d0e715a9
Publikováno v:
Molecules, Vol 29, Iss 8, p 1789 (2024)
Increased oxidative stress is one of the critical pathologies inducing age-related macular degeneration (AMD), characterized by retinal pigment epithelial (RPE) cell damage and death. The unbalanced acetylation and deacetylation of histones have been
Externí odkaz:
https://doaj.org/article/a0684d0a952949ebaf78f0617e6327ac
Autor:
Xueping Lei, Zhan Li, Yihang Zhong, Songpei Li, Jiacong Chen, Yuanyu Ke, Sha Lv, Lijuan Huang, Qianrong Pan, Lixin Zhao, Xiangyu Yang, Zisheng Chen, Qiudi Deng, Xiyong Yu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 10, Pp 3877-3890 (2022)
Metastasis is crucial for the mortality of non-small cell lung carcinoma (NSCLC) patients. The epithelial–mesenchymal transition (EMT) plays a critical role in regulating tumor metastasis. Glioma-associated oncogene 1 (Gli1) is aberrantly active in
Externí odkaz:
https://doaj.org/article/8738c66daefe40ffb8d05dd35bfd3cff
Autor:
Wenyan Xu, Lingran Du, Lina Yu, Huiyu Cen, Fangyu Lin, Siran Wang, Zhixiong Ruan, Zhongxiao Lin, Xin Zhang, Na Zhou, Jishuo Chang, Xiyong Yu, Lingmin Zhang, Lu Liang
Publikováno v:
MedComm, Vol 4, Iss 4, Pp n/a-n/a (2023)
Abstract Gene therapy has emerged as a potential approach for lung cancer therapy. However, the application of gene therapy is still limited by their properties, such as low specificity to the cancer cells, negatively charged groups, short systemic c
Externí odkaz:
https://doaj.org/article/fe234a53a96b4dbcb7748a05d1b4a2f0
Autor:
Lu Liang, Huiyu Cen, Jionghua Huang, Aiping Qin, Wenyan Xu, Siran Wang, Zhijun Chen, Lin Tan, Qiqi Zhang, Xiyong Yu, Xin Yang, Lingmin Zhang
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-19 (2022)
Abstract Background Lung cancer is one of the fatal cancers worldwide, and over 60% of patients are lung adenocarcinoma (LUAD). Our clinical data demonstrated that DNA methylation of the promoter region of miR-126-3p was upregulated, which led to the
Externí odkaz:
https://doaj.org/article/c052657fd26c4a75be6ea88e1c69d281
Autor:
Lu Liang, Wenyan Xu, Ao Shen, Xiaomei Fu, Huiyu Cen, Siran Wang, Zhongxiao Lin, Lingmin Zhang, Fangyu Lin, Xin Zhang, Na Zhou, Jishuo Chang, Zhe‐Sheng Chen, Chuwen Li, Xiyong Yu
Publikováno v:
MedComm, Vol 4, Iss 3, Pp n/a-n/a (2023)
Abstract The balance of M1/M2 macrophage polarization plays an important role in regulating inflammation during acute lung injury (ALI). Yes‐associated protein (YAP1) is a key protein in the Hippo–YAP1 signaling pathway and is involved in macroph
Externí odkaz:
https://doaj.org/article/c0a8e15706c04052bcee8049586e74ef
Autor:
Hang Song, Jianye Zhang, Bin Liu, Jing Xu, Biao Cai, Hai Yang, Julia Straube, Xiyong Yu, Teng Ma
Publikováno v:
Biomarker Research, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract Epigenetics including DNA and RNA modifications have always been the hotspot field of life sciences in the post-genome era. Since the first mapping of N6-methyladenosine (m6A) and the discovery of its widespread presence in mRNA, there are a
Externí odkaz:
https://doaj.org/article/2abf04dc27024f74a6701cb11119213f