Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Xi-xiu Xie"'
Autor:
Ling-Jie Li, Xiao-Ying Sun, Ya-Ru Huang, Shuai Lu, Yu-Ming Xu, Jing Yang, Xi-Xiu Xie, Jie Zhu, Xiao-Yun Niu, Dan Wang, Shi-Yu Liang, Xiao-Yu Du, Sheng-Jie Hou, Xiao-Lin Yu, Rui-Tian Liu
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-17 (2024)
Abstract Background Deoxyribonuclease 2 (DNase II) plays a key role in clearing cytoplasmic double-stranded DNA (dsDNA). Deficiency of DNase II leads to DNA accumulation in the cytoplasm. Persistent dsDNA in neurons is an early pathological hallmark
Externí odkaz:
https://doaj.org/article/7a9b0bec679c43d4b8d1202c43f3c6dc
Autor:
Xiao-yun Niu, Xi-xiu Xie, Hou-zhen Tuo, Cui-ping Lv, Ya-ru Huang, Jie Zhu, Shi-yu Liang, Xiao-yu Du, Cheng-gang Yang, Sheng-jie Hou, Xiao-ying Sun, Ling-jie Li, Fang Cui, Qi-xin Huang, Ying-bo Jia, Yu-jiong Wang, Rui-tian Liu
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-15 (2024)
Abstract The neurotoxic α-synuclein (α-syn) oligomers play an important role in the occurrence and development of Parkinson’s disease (PD), but the factors affecting α-syn generation and neurotoxicity remain unclear. We here first found that thr
Externí odkaz:
https://doaj.org/article/74621297ce3f44dbbbe78cb2be9d79f1
Autor:
Ya-ru Huang, Xi-xiu Xie, Jing Yang, Xiao-ying Sun, Xiao-yun Niu, Cheng-gang Yang, Ling-jie Li, Lun Zhang, Dan Wang, Chun-yu Liu, Sheng-jie Hou, Chen-yang Jiang, Yu-ming Xu, Rui-tian Liu
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112624- (2023)
Summary: Amyloid-β (Aβ) plays an important role in the neuropathology of Alzheimer’s disease (AD), but some factors promoting Aβ generation and Aβ oligomer (Aβo) neurotoxicity remain unclear. We here find that the levels of ArhGAP11A, a Ras ho
Externí odkaz:
https://doaj.org/article/0fc98a5893394101a62f5db921a73f36
Autor:
Ya-ru Huang, Xi-xiu Xie, Mei Ji, Xiao-lin Yu, Jie Zhu, Ling-xiao Zhang, Xiao-ge Liu, Chen Wei, Gang Li, Rui-tian Liu
Publikováno v:
Neurobiology of Disease, Vol 124, Iss , Pp 202-217 (2019)
It has been suggested that aggregation of α-synuclein (α-syn) into oligomers leads to neurodegeneration in Parkinson's disease (PD), but intravenous immunoglobulin (IVIG) which contains antibodies against α-syn monomers and oligomers fails to trea
Externí odkaz:
https://doaj.org/article/e32fd0b6658847ebacb36342141d1ef6
Autor:
Mei Ji, Xi-xiu Xie, Dong-qun Liu, Xiao-lin Yu, Yue Zhang, Ling-Xiao Zhang, Shao-wei Wang, Ya-ru Huang, Rui-tian Liu
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-15 (2018)
Abstract Background Truncated mis-disordered tau protein plays an important role in the pathogenesis of Alzheimer’s disease (AD) and frontotemporal dementia (FTD). Tau294–305, an epitope in the truncated tau, is essential for pathological tau-tau
Externí odkaz:
https://doaj.org/article/f50953cb30a846db91d8dca212459126
Autor:
Shao-wei Wang, Dong-qun Liu, Ling-xiao Zhang, Mei Ji, Yang-xin Zhang, Quan-xiu Dong, Shu-ying Liu, Xi-xiu Xie, Rui-tian Liu
Publikováno v:
Alzheimer’s Research & Therapy, Vol 9, Iss 1, Pp 1-14 (2017)
Abstract Background β-Amyloid peptide (Aβ) oligomers are initial factors used to induce Alzheimer’s disease (AD) development, and Aβ monomers have normal physiological function. The antibodies or vaccines against Aβ monomers have serious proble
Externí odkaz:
https://doaj.org/article/9bafd0a82e1747aca5d6184a9c0aac8e
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8645 (2020)
α-synuclein (α-syn) is a protein associated with the pathogenesis of Parkinson’s disease (PD), the second most common neurodegeneration disease with no effective treatment. However, how α-syn drives the pathology of PD remains elusive. Recent st
Externí odkaz:
https://doaj.org/article/7b1737689bac4f6ba52fbc5118d4dc65
Autor:
Jie Zhu, Shuai Lu, Yu ling Wang, Ting rui Yang, Xiao-lin Yu, Mei Ji, Er hei Dai, Bin Wang, Guangwen Yang, Xi xiu Xie, Xue han Shi, Xi ming Fu, Chang wen Ke, Lei Zhao, Jian Xue, Rui-tian Liu, Dong qun Liu, Bi xia Ke, Cui Lv, Hui xia Gao, Chun guo Jiang, Lun Zhang, Sheng jie Hou
Publikováno v:
Cell reports, 34(4):108666
Cell Reports
Cell Reports
Although vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are under development, the antigen epitopes on the virus and their immunogenicity are poorly understood. Here, we simulate the 3D structures and predict the B cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::385e2aed4120f119b84b7ce2e5ef5823
https://repository.publisso.de/resource/frl:6427845
https://repository.publisso.de/resource/frl:6427845
Autor:
Xi-xiu Xie, Lena Björkman, Jonas Mårtensson, Martina Sundqvist, A. Manandhar, Loukas Ieremias, L. Linjie, Huamei Forsman, Trond Ulven
Neutrophils express many G protein-coupled receptors (GPCRs) including the two formyl peptide receptors (FPR1 and FPR2) and the medium chain fatty acid receptor GPR84. The FPRs are known to define a hierarchy among neutrophil GPCRs, i.e., the GPCR-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df7639c3f2237a976883a768febfcd77
https://doi.org/10.1101/2020.11.13.381582
https://doi.org/10.1101/2020.11.13.381582
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 8645, p 8645 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 8645, p 8645 (2020)
α-synuclein (α-syn) is a protein associated with the pathogenesis of Parkinson’s disease (PD), the second most common neurodegeneration disease with no effective treatment. However, how α-syn drives the pathology of PD remains elusive. Recent st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f98ed67f4e9b8d58f953dbca42a37bf
https://pubmed.ncbi.nlm.nih.gov/33212758
https://pubmed.ncbi.nlm.nih.gov/33212758