Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Xi-Ying Zhao"'
Publikováno v:
Chemical and Pharmaceutical Bulletin. 60:1076-1082
The addition of 4 eq of chloral to osmundalactone (4S,5R)-4 gave quantitative formation of the hemiacetal derivative (4S,5R)-8, which was treated with methane sulfonic acid to afford the intramolecular Micheal addition product (+)-(3S,4S,5R)-9 posses
Publikováno v:
Tetrahedron. 63:10140-10148
(±)-(4,5-anti)-4-Benzyloxy-5-hydroxy-(2E)-hexenoic acid 6 was subjected to δ-lactonization in the presence of 2,4,6-trichlorobenzoyl chloride and pyridine to give the α,β-unsaturated-δ-lactone congener (±)-7 (87% yield) accompanied by trans–c
Autor:
Fumio Hashimoto, Wen-mei Yan, Toshihiro Nohara, Shinobu Sakurada, Junei Kinjo, Toyokichi Yoshizawa, Yu-Ming Chi, Motoyuki Nakamura, Xi-Ying Zhao
Publikováno v:
Biological and Pharmaceutical Bulletin. 29:580-584
Our recent study demonstrated that the dimeric structure of alpha-truxillic acid derivatives played an important role in the expression of their anti-inflammatory activities. In the present report, to investigate the correlation between the structure
Autor:
Toyokichi Yoshizawa, Toshihiro Nohara, Xi Ying Zhao, Motoyuki Nakamura, Fumio Hashimoto, Wen Mei Yan, Yu Ming Chi, Shinobu Sakurada, Junei Kinjo
Publikováno v:
Biological and Pharmaceutical Bulletin. 29:489-493
The oral anti-inflammatory activity of 4,4'-dihydroxy-alpha-truxillic acid (1) was compared with that of two other nonsteroidal anti-inflammatory drugs, loxoprofen sodium (LOX) and diclofenac sodium (DIC). The activity of 1 against the inflammatory p
Autor:
Wen Mei Yan, Toshihiro Nohara, Motoyuki Nakamura, Xi Ying Zhao, Yu-Ming Chi, Junei Kinjo, Toyokichi Yoshizawa, Fumio Hashimoto, Shinobu Sakurada
Publikováno v:
Biological and Pharmaceutical Bulletin. 28:1989-1991
To determine the antinociceptive mechanism of incarvillateine (INCA), the opiate antagonists nor-binaltorphimine (nor-BNI), beta-funaltrexamine (beta-FNA) and naltrindole (NTI) were pretreated prior to its injection in a formalin test. The antinocice
Publikováno v:
Chemicalpharmaceutical bulletin. 60(8)
The addition of 4 eq of chloral to osmundalactone (4S,5R)-4 gave quantitative formation of the hemiacetal derivative (4S,5R)-8, which was treated with methane sulfonic acid to afford the intramolecular Micheal addition product (+)-(3S,4S,5R)-9 posses
Autor:
Motoyuki Nakamura, Yu-Ming Chi, Wen Mei Yan, Yu Cheng Chi, Toshihiro Nohara, Toyokichi Yoshizawa, Fumio Hashimoto, Junei Kinjo, Xi-Ying Zhao
Publikováno v:
Chemicalpharmaceutical bulletin. 53(11)
Method for rapid quantitative analysis of incarvillateine in Incarvillea sinensis by high-performance liquid chromatography (HPLC) has been developed. The sample preparation involves solid phase extraction (SPE) with a mixed-mode reversed-phase and c
Autor:
Junei Kinjo, Fumio Hashimoto, Motoyuki Nakamura, Wen Mei Yan, Toshihiro Nohara, Xi Ying Zhao, Yu Ming Chi, Shinobu Sakurada, Toyokichi Yoshizawa
Publikováno v:
Biologicalpharmaceutical bulletin. 28(9)
The anti-inflammatory activities of alpha-truxillic acid (1) and 4,4'-dihydroxy-alpha-truxillic acid (2) as well as their monomer components (E)-cinnamic acid (3) and (E)-p-coumaric acid (4) were evaluated in the formalin test. alpha-Truxillic acid (
Autor:
Motoyuki Nakamura, Fumio Hashimoto, Junei Kinjo, Toyokichi Yoshizawa, Wen Mei Yan, Xi Ying Zhao, Toshihiro Nohara, Yu Ming Chi
Publikováno v:
Chemical and Pharmaceutical Bulletin. 53:1178-1179
A novel monoterpene alkaloid, named incarvillateine E, possessing three moles of incarvilline moieties, has been obtained from the aerial parts of Incarvillea sinensis LAM. (Bignoniaceae). On the basis of spectroscopic evidence, the structure of inca