Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Xi-Rui Zhou"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundRecently, the role of inorganic pyrophosphatase 2 (PPA2) has been remaining merely superficial in many tumors. Hence, the aim was to analyze the potential functions of PPA2 in pan-cancer, focusing on its role in breast cancer.MethodsA syste
Externí odkaz:
https://doaj.org/article/4fcd568102f347c68f1019256676b998
Autor:
Pengfei Pei, Long Chen, Ruru Fan, Xi-Rui Zhou, Shan Feng, Hangrui Liu, Quanqiang Guo, Huiwei Yin, Qiang Zhang, Fude Sun, Liang Peng, Peng Wei, Chengzhi He, Renzhong Qiao, Zai Wang, Shi-Zhong Luo
Publikováno v:
ACS Nano. 16:13783-13799
Anticancer peptides are promising drug candidates for cancer treatment, but the short circulation time and low delivery efficiency limit their clinical applications. Herein, we designed several lasso-like self-assembling anticancer peptides (LASAPs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de64782511475f6851cf0e05449db92
https://doi.org/10.1021/acsnano.2c01014
https://doi.org/10.1021/acsnano.2c01014
Publikováno v:
Bioconjugate chemistry. 32(1)
For HIV/AIDS treatment, the cocktail therapy which uses a combination of anti-retroviral drugs remains the most widely accepted practice. However, the potential drug toxicity, patient tolerability, and emerging drug resistance have limited its long-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332805c9d85852863d4d482cf56bcb4c
https://pubmed.ncbi.nlm.nih.gov/33405891
https://pubmed.ncbi.nlm.nih.gov/33405891
Publikováno v:
Chemical Communications. 54:9051-9054
Here we developed a critical gasotransmitter (H2S) mediated reduction to induce supramolecular self-assembly in multiple living cell lines. Specifically, the reduction converted an azido group to an amine which allowed the formation of intramolecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99522b05172f77a1e8d86e3914446361
https://doi.org/10.1039/c8cc05174g
https://doi.org/10.1039/c8cc05174g
Autor:
Long Chen, Fude Sun, Peng Wei, Shi-Zhong Luo, Lida Xu, Xiufang Ding, Xi-Rui Zhou, Jun-Feng Liang
Publikováno v:
The Journal of Physical Chemistry B. 121:7421-7430
Peptide self-assembly has a profound biological significance since self-assembled bioactive peptides are gifted with improved bioactivity as well as life-span. In this study, peptide self-assembly was investigated using a therapeutic peptide, PTP-7S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14d5c64f2530f147bd6acd92c9cecb33
https://doi.org/10.1021/acs.jpcb.7b03626
https://doi.org/10.1021/acs.jpcb.7b03626
Autor:
Lili Jia, Yanyan Yuan, Ruru Fan, Zhuqing Liu, Long Chen, Shi-Zhong Luo, Xi-Rui Zhou, Qiang Zhang, Changyuan Yu
Publikováno v:
Amino Acids. 49:193-202
Many lytic peptides contain a heptad sequence with leucine or isoleucine residues at “a” and “d” positions. However, their roles in the peptide-induced cytolytic process remain unclear. We have recently reported an anticancer lytic peptide ZX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c94bf104d82dccd9a56d0294eda0065
https://doi.org/10.1007/s00726-016-2350-9
https://doi.org/10.1007/s00726-016-2350-9
Publikováno v:
Chemical Communications. 52:2807-2810
An AIE fluorescent surfactant has been first used to prestain protein by ultrastrong hydrophobic interaction between fluorescent surfactants and proteins, distinguishing from the most widely used poststaining strategies by employing AIE molecules wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c3cb978a6f10b675abe18c41adf5979
https://doi.org/10.1039/c5cc09377e
https://doi.org/10.1039/c5cc09377e
Publikováno v:
Journal of Peptide Science. 21:530-539
Antimicrobial peptides (AMPs) are considered as potential antibiotic substitutes because of their potent activities. Previous studies mainly focused on the effects of peptide charges and secondary structures, but the self-assembly of AMPs was neglect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e429288f32d6900ce3ee2f8d27972ed6
https://doi.org/10.1002/psc.2788
https://doi.org/10.1002/psc.2788
Publikováno v:
International Journal of Peptide Research and Therapeutics. 21:497-502
A novel multiple responsive polymer-peptide bioconjugate, which exhibits responses to calcium ion, pH, and temperature, was presented. In our study, a peptide with calcium ion response was conjugated with a thermo-responsive polymer at the N terminus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bbb010315f14a85d69c683ca14c3526
https://doi.org/10.1007/s10989-015-9473-9
https://doi.org/10.1007/s10989-015-9473-9
Publikováno v:
International journal of pharmaceutics. 528(1-2)
Peptides are considered as a new generation of drugs due to their high structural and functional diversity. However, the development of peptide drugs is always limited by their poor stability and short circulation time. Carriers are applied for pepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b9f6c6a0ef8ed1888d62c6a9913dfb
https://pubmed.ncbi.nlm.nih.gov/28629983
https://pubmed.ncbi.nlm.nih.gov/28629983