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Spinal cord stimulation reduces cardiac pain through microglial deactivation in rats with chronic myocardial ischemia

Autor: Jia-Hao Ren, Yun-Qing Li, Xiaochen Wu, Liu Jingzhen, Jinbao Zhang, Jian Wang, Siyi He, Xi-Qiang Wu, Yi Sun, Mingming Zhang

Publikováno v: Molecular Medicine Reports

Angina pectoris is cardiac pain that is a common clinical symptom often resulting from myocardial ischemia. Spinal cord stimulation (SCS) is effective in treating refractory angina pectoris, but its underlying mechanisms have not been fully elucidate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f5714301f692391eb5b99376d5dec3
https://doi.org/10.3892/mmr.2021.12475

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The molecular mechanism of aminoguanidine-mediated reduction on the brain edema after surgical brain injury in rats

Autor: Wei Hao, Xi-qiang Wu, Rong-tian Xu

Publikováno v: Brain research. 1282

The study investigated the effect of aminoguanidine (AG) on inducible nitric oxide synthase (iNOS), aquaporin-4 (AQP4), malondialdehyde (MDA) and glutathione (GSH) levels in surgical brain injury (SBI) in rats. AG (75, 150 and 300 mg/kg, i.p.) was ad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eec7d3ee96b7b03d248491c7f485631
https://pubmed.ncbi.nlm.nih.gov/19465010

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