Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Xi-Peng Cao"'
Publikováno v:
BMC Neurology, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Clusterin is a multifunctional protein, which is associated with the pathogenesis and the development of Alzheimer’s disease (AD). Compared with normal controls, inconsistent results have yielded in previous studies for concentr
Externí odkaz:
https://doaj.org/article/4e52b9ca580e4c75b0d238264c878bff
Autor:
Xin-Yu Yang, Xiao-He Hou, Yan-Lin Bi, Hao Hu, Xi-Peng Cao, Lan Tan, Jiu-Long Yang, Jin-Tai Yu
Publikováno v:
BMC Neurology, Vol 21, Iss 1, Pp 1-6 (2021)
Abstract Background Anaemia has been reported to be associated with cognitive decline and Alzheimer’s disease (AD), but the associations between anaemia and cerebrospinal fluid (CSF) AD biomarkers are still unknown. This study aimed to investigate
Externí odkaz:
https://doaj.org/article/a84dde9623f14f5cbcc65348fd26624d
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
BackgroundPerturbation of lipid metabolism is associated with Alzheimer’s disease (AD). Heart fatty acid-binding protein (HFABP) is an adipokine playing an important role in lipid metabolism regulation.Materials and methodsTwo datasets separately e
Externí odkaz:
https://doaj.org/article/7362eaa2e2e94bae920adbeaa37f1944
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
BackgroundAlzheimer's disease (AD) and Parkinson's disease (PD) are two of the most common neurodegenerative diseases, and mild cognitive impairment (MCI) is considered a prodromal stage of clinical AD. Animal studies have shown that probiotics can i
Externí odkaz:
https://doaj.org/article/9bf314a635bb4d71b040d8db818b99c8
Autor:
Xing Zhang, Xiao-He Hou, Ya-Hui Ma, Xue-Ning Shen, Xi-Peng Cao, Jing-Hui Song, Lan Tan, Jin-Tai Yu
Publikováno v:
BMC Neurology, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Inflammation plays an important role in atherosclerosis but the contribution of neutrophils to this process is unclear. We sought to assess whether neutrophil count is associated with intracranial atherosclerotic stenosis (ICAS).
Externí odkaz:
https://doaj.org/article/011b68a419704e9da9f9a7fa0ded54fa
Autor:
Kai-Xin Dou, Meng-Shan Tan, Chen-Chen Tan, Xi-Peng Cao, Xiao-He Hou, Qi-Hao Guo, Lan Tan, Vincent Mok, Jin-Tai Yu
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-10 (2018)
Abstract Background Cholinesterase inhibitors and memantine have been approved for management of Alzheimer’s disease (AD), but there has been no consensus about the choice of various types and doses of drugs at different stages. Hence, we compared
Externí odkaz:
https://doaj.org/article/2ff870f033014079b19fc4a5d4bb19db
Autor:
Jie-Qiong Li, Xiang-Zhen Yuan, Hai-Yan Li, Xi-Peng Cao, Jin-Tai Yu, Lan Tan, Wei-An Chen, Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
BMC Medical Genomics, Vol 11, Iss 1, Pp 1-8 (2018)
Abstract Background Plasma neurofilament light (NFL) is a promising biomarker for Alzheimer disease (AD), which increases in the early stage of AD and is associated with the progression of AD. We performed a genome-wide association study (GWAS) of pl
Externí odkaz:
https://doaj.org/article/c41247d47e3b47b2b6f67083c9b38f64
Autor:
Mei-Ling Tian, Xiao-Neng Ni, Jie-Qiong Li, Chen-Chen Tan, Xi-Peng Cao, Lan Tan, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Background: rs9357347 located at the triggering receptor expressed on myeloid cells (TREM) gene cluster could increase TREM2 and TREM-like transcript 1 (TREML1) brain gene expression, which is considered to play a protective role against Alzheimer’
Externí odkaz:
https://doaj.org/article/f2b5a8d5f12a4545855b86b95bfda4bd
Autor:
Ya-Nan Song, Jie-Qiong Li, Chen-Chen Tan, Hui-Fu Wang, Meng-Shan Tan, Xi-Peng Cao, Jin-Tai Yu, Lan Tan, the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
A coding missense mutation (rs3747742) in triggering receptor expressed on myeloid cell-like 2 (TREML2) has been recently proposed as an important protective factor against Alzheimer’s disease (AD). However, the link between TREML2 and AD pathology
Externí odkaz:
https://doaj.org/article/f69369f8821e48dea7f6e537b4d36329
Autor:
Lan Tan, Chen-Chen Tan, Xi-Peng Cao, Alzheimer’s Disease Neuroimaging Initiative, Wei Xu, Juan-Juan Zou
Publikováno v:
Journal of Alzheimer's Disease. 81:1701-1710
Background: It is suggested that not all individuals with elevated Aβ will develop dementia or cognitive impairment. Environment or lifestyle might modulate the association of amyloid pathology with cognition. Insomnia is a risk factor of cognitive