Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Xi-Biao He"'
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
BackgroundFlavonoid monomers are proved to have an anti-inflammatory effect and may also be promising for chronic pain treatment. In the present study, the analgesic effect and the relevant mechanisms of luteoloside, one of the flavonoid monomers, we
Externí odkaz:
https://doaj.org/article/450169574dfb40e1a39a2dd7fdbee37e
Publikováno v:
Stem Cells. 40:1043-1055
Midbrain dopamine (DA) neurons are associated with locomotor and psychiatric disorders. DA phenotype is specified in ancestral neural precursor cells (NPCs) and maintained throughout neuronal differentiation. Here we show that endogenous expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1324df3a3ad5772094b833442bd80c
https://doi.org/10.1093/stmcls/sxac061
https://doi.org/10.1093/stmcls/sxac061
Autor:
Xi-Biao He, Fang Guo, Wei Zhang, Yi Wu, Weidong Le, Hui-Jing Wang, Qinming Zhou, Haozhi Huang
Regulation of dopamine (DA) biosynthesis is critical for the functionalities of midbrain DA neurons. Tyrosine hydroxylase (TH) is the rate-limiting enzyme for dopamine (DA) biosynthesis in midbrain DA neurons. Here we report that DA contents are decr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69e76ac6f6807a171fba7466b1adbbdd
https://doi.org/10.1101/2022.12.01.518657
https://doi.org/10.1101/2022.12.01.518657
Proteotoxic stress is a major stimulus and risk factor for the neuropathogenesis in central nervous system (CNS), which is tightly associated with neurodegenerative diseases. Here, we identify acrylamide (ACR), a type-2 alkene that is commonly detect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2790943e5bff8fcf2b4f25e1d382360
https://doi.org/10.1101/2022.07.29.498756
https://doi.org/10.1101/2022.07.29.498756
Cardiac autophagy serves as a potential mechanism to be genetically, epigenetically and pharmaceutically manipulated to prevent or alleviate pathological conditions in heart diseases. One of the complexities of this manipulation comes from the cellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0163581a98ab68248bca3a22de06b9f3
https://doi.org/10.1101/2022.06.10.495581
https://doi.org/10.1101/2022.06.10.495581
Publikováno v:
Journal of neurochemistryREFERENCES. 161(5)
The close association between astrocytes and microglia causes great difficulties to distinguish their individual roles in innate immune responses in central nervous system. Current chemical-based methods to eliminate microglia in glial cell culture i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85d133c1b0f3c51090762baf52847a83
https://pubmed.ncbi.nlm.nih.gov/35092690
https://pubmed.ncbi.nlm.nih.gov/35092690
Midbrain dopamine (DA) neurons are associated with locomotor and psychiatric disorders. DA subtype is specified in ancestral neural precursor cells (NPCs) and maintained throughout neuronal differentiation. Here we show that endogenous expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b3272e3e5f032e01e9d57088f5b361a
https://doi.org/10.1101/2021.11.12.468365
https://doi.org/10.1101/2021.11.12.468365
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 9, Pp 1-13 (2020)
Cell Death and Disease, Vol 11, Iss 9, Pp 1-13 (2020)
Heart is a multi-cellular organ made up of various cell types interacting with each other. Cardiomyocytes may benefit or suffer from crosstalk with noncardiomyocytes in response to diverse kinds of cardiac stresses. Proteasome dysfunction is a common
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6e35ab2727bc78437fb1e4285e6844
https://doi.org/10.1038/s41419-020-03005-8
https://doi.org/10.1038/s41419-020-03005-8
Aims Remote ischemic conditionings, such as pre- and per-conditioning, are known to provide cardioprotection in animal models of ischemia. However, little is known about the neuroprotection effect of postconditioning after cerebral ischemia. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8fd89c0a66f6e6bb0c83851e2b71e00
https://europepmc.org/articles/PMC6489769/
https://europepmc.org/articles/PMC6489769/
Autor:
Fiona E. Harrison, Chang-Hwan Park, Eun-Hye Lee, Shilpy Dixit, Mirang Kim, Yong Hee Rhee, Xi Biao He, Sang Hun Lee, Seon-Young Kim, Sang Hoon Yi, Taeho Kim
Publikováno v:
Stem Cells. 33:1320-1332
Intracellular Vitamin C (VC) is maintained at high levels in the developing brain by the activity of sodium-dependent VC transporter 2 (Svct2), suggesting specific VC functions in brain development. A role of VC as a cofactor for Fe(II)-2-oxoglutarat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b857bd6ba33abe3d62471c6959ff95
https://doi.org/10.1002/stem.1932
https://doi.org/10.1002/stem.1932