Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Xi- Ping Zhang"'
Autor:
Tatiana Erazo, Chiara M. Evans, Daniel Zakheim, Eren L. Chu, Alice Yunsi Refermat, Zahra Asgari, Xuejing Yang, Mariana Da Silva Ferreira, Sanjoy Mehta, Marco Vincenzo Russo, Andrea Knezevic, Xi-Ping Zhang, Zhengming Chen, Myles Fennell, Ralph Garippa, Venkatraman Seshan, Elisa de Stanchina, Olena Barbash, Connie Lee Batlevi, Christina S. Leslie, Ari M. Melnick, Anas Younes, Michael G. Kharas
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Abstract To identify drivers of sensitivity and resistance to Protein Arginine Methyltransferase 5 (PRMT5) inhibition, we perform a genome-wide CRISPR/Cas9 screen. We identify TP53 and RNA-binding protein MUSASHI2 (MSI2) as the top-ranked sensitizer
Externí odkaz:
https://doaj.org/article/ae7897107ec04e2091ae2adabb8a333a
Autor:
Xi-Ping Zhang
Publikováno v:
Chinese Medicine and Culture, Vol 4, Iss 3, Pp 137-140 (2021)
This article provides an introduction to Michel Boym (1612–1659) and Jean Pierre Abel Rémusat (1788–1832) and examines the research on traditional Chinese medicine (TCM) conducted by the two prominent sinologists. This work points out that Miche
Externí odkaz:
https://doaj.org/article/bbc99bd0a4f947b7a5c0f0fd86713deb
Autor:
Wei Wei, Xiao-Man Fan, Shao-Hui Jia, Xi-Ping Zhang, Zhao Zhang, Xue-Jun Zhang, Jiu-Xun Zhang, Ye-Wang Zhang
Publikováno v:
Frontiers in Nutrition, Vol 8 (2021)
Sea cucumbers are one of many marine echinoderm animals that contain valuable nutrients and medicinal compounds. The bioactive substances in sea cucumbers make them have promising biological and pharmacological properties, including antioxidant, anti
Externí odkaz:
https://doaj.org/article/ab62e90143ea41a5a7d0bdd2a2ce8e71
Autor:
Xi- Ping Zhang, Hong- Seok Jeon
Publikováno v:
Theological Perspective. 220:60-95
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16348b20a9e1bdce34048223bb3500d4
https://doi.org/10.22504/tp.2023.03.220.60
https://doi.org/10.22504/tp.2023.03.220.60
Autor:
Xi-Ping Zhang, Hong-Seok Jeon
Publikováno v:
Religions of Korea. 54:264-294
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::165e05e4405998139f98759a646a18b9
https://doi.org/10.37860/krel.2023.02.54.264
https://doi.org/10.37860/krel.2023.02.54.264
Autor:
Wei Wei, Li-Jian Zhou, Shue Wang, Zheng Zhang, Jia-Ying Huang, Zhao Zhang, Xi-Ping Zhang, Xue-Jun Zhang, Jie Li, Ye-Wang Zhang
Publikováno v:
Frontiers in Chemistry. 10
Katsuwonus pelamispeptide and its complexes have the effect of lowering uric acid (UA)-levels. To identify the effect and possible mechanisms, different concentrations ofKatsuwonus pelamispeptide and its complexes were administered to the zebrafish a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3752a0f9288085cc918b47edd9adbe8c
Autor:
Tatiana Erazo, Chiara M. Evans, Daniel Zakheim, Karen L. Chu, Alice Yunsi Refermat, Zahra Asgari, Xuejing Yang, Mariana Da Silva Ferreira, Sanjoy Mehta, Marco Vincenzo Russo, Andrea Knezevic, Xi-Ping Zhang, Zhengming Chen, Myles Fennell, Ralph Garippa, Venkatraman Seshan, Elisa de Stanchina, Olena Barbash, Connie Lee Batlevi, Christina S. Leslie, Ari M. Melnick, Anas Younes, Michael G. Kharas
Publikováno v:
Nature communications. 13(1)
To identify drivers of sensitivity and resistance to Protein Arginine Methyltransferase 5 (PRMT5) inhibition, we perform a genome-wide CRISPR/Cas9 screen. We identify TP53 and RNA-binding protein MUSASHI2 (MSI2) as the top-ranked sensitizer and drive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be7e429b6aac6d3fecd6a10f5b0a27b5
https://pubmed.ncbi.nlm.nih.gov/36167829
https://pubmed.ncbi.nlm.nih.gov/36167829
Publikováno v:
Ann Transl Med
Background Triple-negative breast cancer (TNBC) is characterized by its aggressiveness and poor prognosis. Docetaxel is the common chemotherapeutic drug used in the treatment of TNBC. However, resistance to docetaxel has limited the effectiveness of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66c8dd4410e4f8681b3b7c1ea3e3e9d3
https://europepmc.org/articles/PMC8506551/
https://europepmc.org/articles/PMC8506551/
Autor:
Alex Phillipou, Ryan G. Kruger, Simon Taylor, Chun-wa Chung, Rab K. Prinjha, Laurie J. Gordon, Robert J. Watson, James Gray, Alex Preston, James J. Foley, Cassie Messenger, Anna K. Bassil, Inmaculada Rioja, James Michael Woolven, Xi-Ping Zhang, Francesco Rianjongdee, Paola Grandi, Jeanne J. Matteo, Anastasia Wyce, Ian D. Wall, Paul Bamborough, Darren Jason Mitchell, Lee Andrew Harrison, Michael T. McCabe, Stephen John Atkinson, Jonathan Thomas Seal, Emmanuel Hubert Demont
Publikováno v:
Journal of medicinal chemistry. 64(15)
The profound efficacy of pan-BET inhibitors is well documented, but these epigenetic agents have shown pharmacology-driven toxicity in oncology clinical trials. The opportunity to identify inhibitors with an improved safety profile by selective targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4e26e07fd3767cf6b96980599351c38
https://pubmed.ncbi.nlm.nih.gov/34255512
https://pubmed.ncbi.nlm.nih.gov/34255512
Publikováno v:
Pathology & Oncology Research. 25:827-835
With abilities to renew themselves and lead to heterogeneity of tumors, cancer stem cells (CSCs) are similar to stem cells. As three leading causes of death that endanger women's health, breast cancer, ovarian cancer and cervical cancer are character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::686cd60d69ff318b1b8590225a6628f9
https://doi.org/10.1007/s12253-018-0448-y
https://doi.org/10.1007/s12253-018-0448-y