Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Xi'e Wang"'
Autor:
Haitao Zhou, Shanshan Ding, Chuanxin Sun, Jiahui Fu, Dong Yang, Xi'e Wang, Chih-chen Wang, Lei Wang
Publikováno v:
Frontiers in Nutrition, Vol 8 (2022)
Lycium barbarum berry (Ningxia Gouqi, Fructus lycii, goji berry, or wolfberry), as a traditional Chinese herb, was recorded beneficial for longevity in traditional Chinese medical scriptures and currently is a natural dietary supplement worldwide. Ho
Externí odkaz:
https://doaj.org/article/f398f58f265b4f6ab2b4fc4d99615f65
Autor:
Yini Zhang, Tao Li, Lihui Zhang, Fugen Shangguan, Guizhi Shi, Xun Wu, Ya Cui, Xi'e Wang, Xi Wang, Yongzhang Liu, Bin Lu, Taotao Wei, Chih-chen Wang, Lei Wang
Publikováno v:
EBioMedicine, Vol 41, Iss , Pp 408-419 (2019)
Background: Endoplasmic reticulum (ER) oxidoreductin-1α (Ero1α) and protein disulfide isomerase (PDI) constitute the pivotal pathway of oxidative protein folding, and are highly expressed in many cancers. However, whether targeting the functional i
Externí odkaz:
https://doaj.org/article/21e7f0012b7d42528a29c91a9074bbf3
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105529 (2014)
Peroxiredoxin 4 (Prx4) is the only endoplasmic reticulum localized peroxiredoxin. It functions not only to eliminate peroxide but also to promote oxidative protein folding via oxidizing protein disulfide isomerase (PDI). In Prx4-mediated oxidative pr
Externí odkaz:
https://doaj.org/article/f3896079877b4ab29a17910a3dc878be
Autor:
Chih-chen Wang, Xi'e Wang, Junyu Xiao, Jianchao Zhang, Yangyang Wei, Lei Wang, Pulan Liu, Xinxin Chen
Publikováno v:
Proc Natl Acad Sci U S A
Family with sequence similarity 20C (Fam20C), the major protein kinase in the secretory pathway, generates the vast majority of the secreted phosphoproteome. However, the regulatory mechanisms of Fam20C transport, secretion, and function remain large
Autor:
Yongzhang Liu, Fugen Shangguan, Ya Cui, Tao Li, Lihui Zhang, Xun Wu, Chih-chen Wang, Xi'e Wang, Taotao Wei, Bin Lu, Lei Wang, Guizhi Shi, Xi Wang, Yini Zhang
Publikováno v:
EBioMedicine
Background Endoplasmic reticulum (ER) oxidoreductin-1α (Ero1α) and protein disulfide isomerase (PDI) constitute the pivotal pathway of oxidative protein folding, and are highly expressed in many cancers. However, whether targeting the functional in
Autor:
Jizhong Lou, Yu Liu, Jiaojiao Yu, Jianchao Zhang, Likun Wang, Tao Li, Xi Wang, Chih-chen Wang, Lei Wang, Guizhi Shi, Xi'e Wang
Publikováno v:
EMBO J
Accumulated unfolded proteins in the endoplasmic reticulum (ER) trigger the unfolded protein response (UPR) to increase ER protein folding capacity. ER proteostasis and UPR signaling need to be regulated in a precise and timely manner. Here, we ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d23b531cb21ed9c89c11f3b29d4229
https://europepmc.org/articles/PMC7232009/
https://europepmc.org/articles/PMC7232009/
Autor:
Xinxin Chen, Jianchao Zhang, Liu, Pulan, Yangyang Wei, Xi'e Wang, Junyu Xiao, Chih-chen Wang, Lei Wang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 8/10/2021, Vol. 118 Issue 32, p1-11, 11p
Autor:
Xi'e Wang, Chih-chen Wang, Tao Li, Guang-Hui Liu, Jiping Yang, Hong Zhang, Xun Wu, Lei Wang, Jingqi Fang, Gangming Zhang
Publikováno v:
Aging Cell
Summary Metformin, an FDA‐approved antidiabetic drug, has been shown to elongate lifespan in animal models. Nevertheless, the effects of metformin on human cells remain unclear. Here, we show that low‐dose metformin treatment extends the lifespan
Autor:
Xinxin Chen, Jiaojiao Yu, Junyu Xiao, Lei Wang, Chih-chen Wang, Xi Wang, Jianchao Zhang, Qinyu Zhu, Jifeng Wang, Xi'e Wang
Publikováno v:
The EMBO journal. 37(14)
Family with sequence similarity 20C (Fam20C), the physiological Golgi casein kinase, phosphorylates numerous secreted proteins that are involved in a wide variety of biological processes. However, the role of Fam20C in regulating proteins in the endo
Publikováno v:
Journal of Biological Chemistry. 289:31188-31199
Protein-disulfide isomerase (PDI) and sulfhydryl oxidase endoplasmic reticulum oxidoreductin-1α (Ero1α) constitute the pivotal pathway for oxidative protein folding in the mammalian endoplasmic reticulum (ER). Ero1α oxidizes PDI to introduce disul