Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Xhordi Lleshi"'
Autor:
Patricia Altea-Manzano, Anke Vandekeere, Joy Edwards-Hicks, Mar Roldan, Emily Abraham, Xhordi Lleshi, Ania Naila Guerrieri, Domenica Berardi, Jimi Wills, Jair Marques Junior, Asimina Pantazi, Juan Carlos Acosta, Rosario M. Sanchez-Martin, Sarah-Maria Fendt, Miguel Martin-Hernandez, Andrew J. Finch
Publikováno v:
Molecular cell. 82(23)
Supplemental information can be found online at https://doi.org/10.1016/j.molcel.2022.10.005
ACKNOWLEDGMENTS P.A.-M was supported by a Marie Sklodowska-Curie Actions individual fellowship and the Beug Foundation. A.V. was supported by Fonds Wete
ACKNOWLEDGMENTS P.A.-M was supported by a Marie Sklodowska-Curie Actions individual fellowship and the Beug Foundation. A.V. was supported by Fonds Wete
Autor:
Hazel C. Thoms, Rory R. Duncan, Ian T Lobb, Jimi Wills, Lesley A. Stark, Pierre Morin, Kirsty J. Martin, Karl C.F. Olsen, Xhordi Lleshi
Publikováno v:
Lobb, I T, Morin, P, Martin, K J, Thoms, H, Wills, J, Lieshi, X, Olsen, K C F, Duncan, R R & Stark, L A 2020, ' A role for the autophagic receptor, SQSTM1/p62, in trafficking NF-κB/RelA to nucleolar aggresomes ', Molecular Cancer Research . https://doi.org/10.1158/1541-7786.MCR-20-0336
Elevated NF-κB activity is a contributory factor in many hematologic and solid malignancies. Nucleolar sequestration of NF-κB/RelA represses this elevated activity and mediates apoptosis of cancer cells. Here, we set out to understand the mechanism