Probing the Influence of Linker Length and Flexibility in the Design and Synthesis of New Trehalase Inhibitors

Autor: Giampiero D’Adamio, Matilde Forcella, Paola Fusi, Paolo Parenti, Camilla Matassini, Xhenti Ferhati, Costanza Vanni, Francesca Cardona

Publikováno v: Molecules, Vol 23, Iss 2, p 436 (2018)

This work aims to synthesize new trehalase inhibitors selective towards the insect trehalase versus the porcine trehalase, in view of their application as potentially non-toxic insecticides and fungicides. The synthesis of a new pseudodisaccharide mi

Externí odkaz: https://doaj.org/article/66b0b8bd72664dc7a846c27618d844b0

Emerging glyco-based strategies to steer immune responses

Autor: Robert Sackstein, Barbara Richichi, Marco Marradi, Alba Silipo, Milena Marinović-Cincović, Wiesław Kaca, Francesco Berti, Urban Švajger, Ondřej Vaněk, Rikard Holmdahl, Sandra J. van Vliet, Fabrizio Chiodo, Katarzyna Durlik, Celso A. Reis, Dragana Jovanovic, Marko Anderluh, Xhenti Ferhati, Josè Juan Reina-Martin, Anna Bzducha-Wróbel, Luigi Lay, Fumiichiro Yamamoto, Laura Polito, Musa Özil, Federica Compostella, Cinzia Colombo

Publikováno v: Anderluh, M, Berti, F, Bzducha-Wróbel, A, Chiodo, F, Colombo, C, Compostella, F, Durlik, K, Ferhati, X, Holmdahl, R, Jovanovic, D, Kaca, W, Lay, L, Marinovic-Cincovic, M, Marradi, M, Ozil, M, Polito, L, Reina-Martin, J J, Reis, C A, Sackstein, R, Silipo, A, Švajger, U, Vaněk, O, Yamamoto, F, Richichi, B & van Vliet, S J 2021, ' Emerging glyco-based strategies to steer immune responses ', FEBS Journal, vol. 288, no. 16, pp. 4746-4772 . https://doi.org/10.1111/febs.15830
FEBS Journal
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
FEBS Journal, 288(16), 4746-4772. Wiley-Blackwell Publishing Ltd
The FEBS Journal
The Febs Journal

Glycan structures are common posttranslational modifications of proteins, which serve multiple important structural roles (for instance in protein folding), but also are crucial participants in cell–cell communications and in the regulation of immu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab5acafe3744a8d851e52741aa061a5
https://research.vumc.nl/en/publications/948d0f43-7112-475a-90f6-a02b2a013b6d

Recent advances on smart glycoconjugate vaccines in infections and cancer

Autor: Musa Özil, José J. Reina, Fabrizio Chiodo, Barbara Richichi, Ondřej Vaněk, Katarzyna Durlik, Cinzia Colombo, Sandra J. van Vliet, Alba Silipo, Federica Compostella, Anna Bzducha-Wróbel, Xhenti Ferhati, Francesco Berti, Milena Marinović-Cincović, Robert Sackstein, Rikard Holmdahl, Luigi Lay, Fumiichiro Yamamoto, Dragana Jovanovic, Marko Anderluh, Wiesław Kaca, Urban Švajger, Marco Marradi, Celso A. Reis, Laura Polito

Publikováno v: Anderluh, M, Berti, F, Bzducha-Wróbel, A, Chiodo, F, Colombo, C, Compostella, F, Durlik, K, Ferhati, X, Holmdahl, R, Jovanovic, D, Kaca, W, Lay, L, Marinovic-Cincovic, M, Marradi, M, Ozil, M, Polito, L, Reina, J J, Reis, C A, Sackstein, R, Silipo, A, Švajger, U, Vaněk, O, Yamamoto, F, Richichi, B & van Vliet, S J 2021, ' Recent advances on smart glycoconjugate vaccines in infections and cancer ', FEBS Journal . https://doi.org/10.1111/febs.15909, https://doi.org/10.1111/febs.15909
The FEBS Journal

Vaccination is one of the greatest achievements in biomedical research preventing death and morbidity in many infectious diseases through the induction of pathogen-specific humoral and cellular immune responses. Currently, no effective vaccines are a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdec780061ea0dfaa799b3808c0d25b8
https://doi.org/10.1111/febs.15909

Probing the Influence of Linker Length and Flexibility in the Design and Synthesis of New Trehalase Inhibitors

Autor: Paola Fusi, Xhenti Ferhati, Francesca Cardona, Costanza Vanni, Paolo Parenti, Matilde Forcella, Camilla Matassini, Giampiero D'Adamio

Publikováno v: Molecules; Volume 23; Issue 2; Pages: 436
Molecules, Vol 23, Iss 2, p 436 (2018)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry

This work aims to synthesize new trehalase inhibitors selective towards the insect trehalase versus the porcine trehalase, in view of their application as potentially non-toxic insecticides and fungicides. The synthesis of a new pseudodisaccharide mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d378095490330ff36a1e100de8e59194

Polyhydroxyamino-Piperidine-Type Iminosugars and Pipecolic Acid Analogues from aD-Mannose-Derived Aldehyde

Autor: Antonio J. Moreno-Vargas, Inmaculada Robina, Francesca Cardona, Stefania Mirabella, Cristina Faggi, Elena Moreno-Clavijo, Xhenti Ferhati, Andrea Goti, Camilla Matassini

Publikováno v: European Journal of Organic Chemistry. 2014:5419-5432

A general strategy for the synthesis of diversely substituted 3,4,5-trihydroxypiperidines (including two natural products), 5-amino-3,4-dihydroxypiperidines, 3,4,5-trihydroxypipecolic acids, and 2-(aminomethyl)-3,4,5-trihydroxypiperidines is reported

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::863e9e484ad32d48364b4257998b6073
https://doi.org/10.1002/ejoc.201402427