Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Xenia Puig"'
Autor:
Rainer Rupprecht, Arpit Kumar Pradhan, Marco Kufner, Lisa Marie Brunner, Caroline Nothdurfter, Simon Wein, Jens Schwarzbach, Xenia Puig, Christian Rupprecht, Gerhard Rammes
Publikováno v:
European Archives of Psychiatry and Clinical Neuroscience.
There is need for novel fast acting treatment options in affective disorders. 3α-reduced neurosteroids such as allopregnanolone are powerful positive allosteric modulators of GABA
Autor:
Karin Taş, Beatrice Dalla Volta, Christina Lindner, Omar El Bounkari, Kathleen Hille, Yuan Tian, Xènia Puig-Bosch, Markus Ballmann, Simon Hornung, Martin Ortner, Sophia Prem, Laura Meier, Gerhard Rammes, Martin Haslbeck, Christian Weber, Remco T. A. Megens, Jürgen Bernhagen, Aphrodite Kapurniotu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Amyloid self-assembly is linked to type 2 diabetes and Alzheimer’s disease. Here the authors designed constrained peptides which are nanomolar amyloid inhibitors of the key polypeptides IAPP and Aβ42 and act via supramolecular nanofiber co-assembl
Externí odkaz:
https://doaj.org/article/3b23585f88cb4b29866249912e9885cc
Autor:
Xènia Puig-Bosch, Markus Ballmann, Stefan Bieletzki, Bernd Antkowiak, Uwe Rudolph, Hanns Ulrich Zeilhofer, Gerhard Rammes
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 9056 (2023)
Neurosteroids and benzodiazepines are modulators of the GABAA receptors, thereby causing anxiolysis. Furthermore, benzodiazepines such as midazolam are known to cause adverse side-effects on cognition upon administration. We previously found that mid
Externí odkaz:
https://doaj.org/article/ab747eb6bb664de089112577bb31e49d