Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Xenia G. Borggaard"'
Autor:
Xenia G. Borggaard, Malene H. Nielsen, Jean-Marie Delaisse, Christina M. Andreasen, Thomas L. Andersen
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The strictly regulated bone remodeling process ensures that osteoblastic bone formation is coupled to osteoclastic bone resorption. This coupling is regulated by a panel of coupling factors, including clastokines promoting the recruitment, expansion,
Externí odkaz:
https://doaj.org/article/cbb3ebbbab6049a097135149ac2d3c11
Autor:
Bilal M. El-Masri, Majken I. Kejser, Line L. Sørensen, Xenia G. Borggaard, Malene H. Nielsen, Lene W.T. Boel, Kaja S. Laursen, Jesper S. Thomsen, Christina M. Andreasen, Thomas L. Andersen
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100651- (2020)
Externí odkaz:
https://doaj.org/article/48f900fb622e4a9cbf51103a1be4f976
Autor:
Xenia G. Borggaard, Jean-Paul Roux, Jean-Marie Delaisse, Pascale Chavassieux, Christina M. Andreasen, Thomas L. Andersen
Publikováno v:
Borggaard, X G, Roux, J P, Delaisse, J M, Chavassieux, P, Andreasen, C M & Andersen, T L 2022, ' Alendronate prolongs the reversal-resorption phase in human cortical bone remodeling ', Bone, vol. 160, 116419 . https://doi.org/10.1016/j.bone.2022.116419
Despite their ability to reduce fracture-risk and increase Bone Mineral Density (BMD) in osteoporotic women, bisphosphonates are reported to reduce formation of new bone. Reduced bone formation has been suggested to lead to accumulation of microfract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7eff1ed774f50127f901cc1f0843fc
https://pure.au.dk/portal/da/publications/alendronate-prolongs-the-reversalresorption-phase-in-human-cortical-bone-remodeling(dc2116e9-4951-4d14-a167-ec04ec639c8b).html
https://pure.au.dk/portal/da/publications/alendronate-prolongs-the-reversalresorption-phase-in-human-cortical-bone-remodeling(dc2116e9-4951-4d14-a167-ec04ec639c8b).html
Publikováno v:
Søe, K, Delaissé, J-M & Goldberg Borggaard, X 2021, ' Osteoclast formation at the bone marrow/bone surface interface: Importance of structural elements, matrix, and intercellular communication ', Seminars in Cell and Developmental Biology, vol. 112, pp. 8-15 . https://doi.org/10.1016/j.semcdb.2020.05.016
Osteoclasts, the multinucleated cells responsible for bone resorption, have an enormous destructive power which demands to be kept under tight control. Accordingly, the identification of molecular signals directing osteo- clastogenesis and switching
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a615558a9e00852f9e02b16b468a53
https://doi.org/10.1016/j.semcdb.2020.05.016
https://doi.org/10.1016/j.semcdb.2020.05.016
Autor:
Lene Warner Thorup Boel, Kaja Søndergaard Laursen, Line L. Sørensen, Bilal M. El-Masri, Thomas Levin Andersen, Jesper Skovhus Thomsen, Xenia G. Borggaard, Majken I. Kejser, Christina Møller Andreasen, Malene H. Nielsen
Publikováno v:
El.Masri, B M, Kejser, M I, Lindholm Sørensen, L, Goldborg Borggaard, X, Nielsen, M H, Boel, L W T, Laursen, K S, Thomsen, J S, Andreasen, C M & Levin Andersen, T 2020, ' Prolongation of the reversal-resorption phase leads to increased cortical porosity in men and women ', Bone Reports, bind 13, nr. Suppl., COP25, s. 14 . https://doi.org/10.1016/j.bonr.2020.100651
Bone Reports, Vol 13, Iss, Pp 100651-(2020)
Bone Reports, Vol 13, Iss, Pp 100651-(2020)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2bcff5a04692f04a4dc295d4a7ad6ab
https://portal.findresearcher.sdu.dk/da/publications/b462a5ac-2262-4645-9b9e-b2b8a12f91d1
https://portal.findresearcher.sdu.dk/da/publications/b462a5ac-2262-4645-9b9e-b2b8a12f91d1
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 16
International Journal of Molecular Sciences, Vol 21, Iss 5924, p 5924 (2020)
Goldberg Borggaard, X, Pirapaharan, D C, Delaissé, J-M & Søe, K 2020, ' Osteoclasts’ ability to generate trenches rather than pits depends on high levels of active cathepsin K and efficient clearance of resorption products ', International Journal of Molecular Sciences, vol. 21, no. 16, 5924 . https://doi.org/10.3390/ijms21165924
Volume 21
Issue 16
International Journal of Molecular Sciences, Vol 21, Iss 5924, p 5924 (2020)
Goldberg Borggaard, X, Pirapaharan, D C, Delaissé, J-M & Søe, K 2020, ' Osteoclasts’ ability to generate trenches rather than pits depends on high levels of active cathepsin K and efficient clearance of resorption products ', International Journal of Molecular Sciences, vol. 21, no. 16, 5924 . https://doi.org/10.3390/ijms21165924
Until recently, it was well-accepted that osteoclasts resorb bone according to the resorption cycle model. This model is based on the assumption that osteoclasts are immobile during bone erosion, allowing the actin ring to be firmly attached and ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49f224b87c65d36725af674e123a25b1
https://doi.org/10.3390/ijms21165924
https://doi.org/10.3390/ijms21165924
Autor:
Xenia G. Borggaard, Thomas Levin Andersen, Nathan J. Pavlos, Jesper Skovhus Thomsen, Jean-Marie Delaissé, Finn Skou Pedersen, Annemarie Brüel, Ernst-Martin Füchtbauer, Anaïs Marie Julie Møller, Kent Søe
Publikováno v:
Moller, A M J, Fuchtbauer, E-M, Bruel, A, Andersen, T L, Borggaard, X G, Pavlos, N J, Thomsen, J S, Pedersen, F S, Delaisse, J-M & Soe, K 2018, ' Septins are critical regulators of osteoclastic bone resorption ', Scientific Reports, vol. 8, 13016 . https://doi.org/10.1038/s41598-018-31159-1
Scientific Reports
Møller, A M J, Füchtbauer, E-M, Brüel, A, Andersen, T L, Borggaard, X G, Pavlos, N J, Thomsen, J S, Pedersen, F S, Delaisse, J-M & Søe, K 2018, ' Septins are critical regulators of osteoclastic bone resorption ', Scientific Reports, vol. 8, no. 1, 13016 . https://doi.org/10.1038/s41598-018-31159-1
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Scientific Reports
Møller, A M J, Füchtbauer, E-M, Brüel, A, Andersen, T L, Borggaard, X G, Pavlos, N J, Thomsen, J S, Pedersen, F S, Delaisse, J-M & Søe, K 2018, ' Septins are critical regulators of osteoclastic bone resorption ', Scientific Reports, vol. 8, no. 1, 13016 . https://doi.org/10.1038/s41598-018-31159-1
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Septins are known to play key roles in supporting cytoskeletal stability, vesicular transport, endo-/exocytosis, stabilizing cellular membranes and forming diffusion barriers. Their function in mammalian cells is poorly investigated. The osteoclast o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de8d3ef97b8e1d67a27d534b211dadd
https://pure.au.dk/ws/files/132891608/s41598_018_31159_1.pdf
https://pure.au.dk/ws/files/132891608/s41598_018_31159_1.pdf