Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Xavier de Bolle"'
Autor:
Emeline Barbieux, Georges Potemberg, François-Xavier Stubbe, Audrey Fraikin, Katy Poncin, Angeline Reboul, Thomas Rouma, Amaia Zúñiga-Ripa, Xavier De Bolle, Eric Muraille
Publikováno v:
PLoS Pathogens, Vol 20, Iss 8, p e1012459 (2024)
Live attenuated vaccines (LAVs) whose virulence would be controlled at the tissue level could be a crucial tool to effectively fight intracellular bacterial pathogens, because they would optimize the induction of protective immune memory while avoidi
Externí odkaz:
https://doaj.org/article/573248d430934f67928a37c38158e756
Autor:
Caroline Servais, Victoria Vassen, Audrey Verhaeghe, Nina Küster, Elodie Carlier, Léa Phégnon, Aurélie Mayard, Nicolas Auberger, Stéphane Vincent, Xavier De Bolle
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Pathogenic Brucella abortus, containing a mix of lipopolysaccharides with or without O-antigen, grows its envelope in a unipolar manner. Here, Servais et al, localize the LPS translocation machinery and identify the main O-antigen ligase in Brucella
Externí odkaz:
https://doaj.org/article/56c54572a73f488bbfcde1fbc33b7752
Publikováno v:
PLoS Pathogens, Vol 19, Iss 7, p e1011471 (2023)
Mitochondria fulfil a plethora of cellular functions ranging from energy production to regulation of inflammation and cell death control. The fundamental role of mitochondria makes them a target of choice for invading pathogens, with either an intrac
Externí odkaz:
https://doaj.org/article/e5a327428193469cb3efde7b061e019f
Autor:
Georges Potemberg, Aurore Demars, Emeline Barbieux, Angéline Reboul, François-Xavier Stubbe, Malissia Galia, Maxime Lagneaux, Audrey Comein, Olivier Denis, David Pérez-Morga, Jean-Marie Vanderwinden, Xavier De Bolle, Eric Muraille
Publikováno v:
PLoS Pathogens, Vol 18, Iss 6, p e1010621 (2022)
Brucellae are facultative intracellular Gram-negative coccobacilli that chronically infect various mammals and cause brucellosis. Human brucellosis is among the most common bacterial zoonoses and the vast majority of cases are attributed to B. melite
Externí odkaz:
https://doaj.org/article/e5d271c769df4d1cb24e8926140a1392
Autor:
Gregory Simpson, Peter N. Thompson, Claude Saegerman, Tanguy Marcotty, Jean-Jacques Letesson, Xavier de Bolle, Jacques Godfroid
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract This study aimed to consolidate current knowledge of wildlife brucellosis in Africa and to analyse available predictors of infection. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were followed. Informatio
Externí odkaz:
https://doaj.org/article/2fcc49c372f4435db4ba6aaa01dcc9db
Autor:
Olga Rivas-Solano, Mathilde Van der Henst, Amanda Castillo-Zeledón, Marcela Suárez-Esquivel, Lohendy Muñoz-Vargas, Zeuz Capitan-Barrios, Nicholas R. Thomson, Esteban Chaves-Olarte, Edgardo Moreno, Xavier De Bolle, Caterina Guzmán-Verri
Publikováno v:
PLoS ONE, Vol 17, Iss 9 (2022)
Brucella abortus is a facultative intracellular pathogen causing a severe zoonotic disease worldwide. The two-component regulatory system (TCS) BvrR/BvrS of B. abortus is conserved in members of the Alphaproteobacteria class. It is related to the exp
Externí odkaz:
https://doaj.org/article/8978fa846faa4d1ca9edc4023fadcdc0
Autor:
Aurore Demars, Armelle Vitali, Audrey Comein, Elodie Carlier, Abdulkader Azouz, Stanislas Goriely, Justine Smout, Véronique Flamand, Mégane Van Gysel, Johan Wouters, Jan Abendroth, Thomas E Edwards, Arnaud Machelart, Eik Hoffmann, Priscille Brodin, Xavier De Bolle, Eric Muraille
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009887 (2021)
Brucellosis is one of the most widespread bacterial zoonoses worldwide. Here, our aim was to identify the effector mechanisms controlling the early stages of intranasal infection with Brucella in C57BL/6 mice. During the first 48 hours of infection,
Externí odkaz:
https://doaj.org/article/0ebdeb0dee1242609d7b967c5f88f4d6
Autor:
Katy Poncin, Agnès Roba, Ravikumar Jimmidi, Georges Potemberg, Antonella Fioravanti, Nayla Francis, Kévin Willemart, Nicolas Zeippen, Arnaud Machelart, Emanuele G. Biondi, Eric Muraille, Stéphane P. Vincent, Xavier De Bolle
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
It is assumed that intracellular pathogenic bacteria must cope with DNA alkylating stress within host cells. Here, Poncin et al. show that the pathogen Brucella abortus does encounter alkylating stress within macrophages, and shed light into the path
Externí odkaz:
https://doaj.org/article/0e9cb03fdb914652b78daf4b8a72caac
Autor:
Aurore Demars, Aurore Lison, Arnaud Machelart, Margaux Van Vyve, Georges Potemberg, Jean-Marie Vanderwinden, Xavier De Bolle, Jean-Jacques Letesson, Eric Muraille
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Live attenuated vaccines play a key role in the control of many human and animal pathogens. Their rational development is usually helped by identification of the reservoir of infection, the lymphoid subpopulations associated with protective immunity
Externí odkaz:
https://doaj.org/article/4f160955635d45c18637bd532bcf3353
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The small molecule (p)ppGpp is commonly produced by bacteria as a signal of nutrient starvation. Here, Ronneau et al. show that (p)ppGpp accumulation in the model bacterium Caulobacter crescentusis modulated by a nitrogen-related phosphotransferase s
Externí odkaz:
https://doaj.org/article/ce77341cf3a34f49abaf776315bfe2b8