Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Xavier Toussay"'
Autor:
Marissa A. Lithopoulos, Xavier Toussay, Shumei Zhong, Liqun Xu, Shamimunisa B. Mustafa, Julie Ouellette, Moises Freitas-Andrade, Cesar H. Comin, Hayam A. Bassam, Adam N. Baker, Yiren Sun, Michael Wakem, Alvaro G. Moreira, Cynthia L. Blanco, Arul Vadivel, Catherine Tsilfidis, Steven R. Seidner, Ruth S. Slack, Diane C. Lagace, Jing Wang, Baptiste Lacoste, Bernard Thébaud
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 22 (2022)
Preterm birth is the leading cause of death in children under 5 years of age. Premature infants who receive life-saving oxygen therapy often develop bronchopulmonary dysplasia (BPD), a chronic lung disease. Infants with BPD are at a high risk of abno
Externí odkaz:
https://doaj.org/article/b460101f4de54091bba25914881e2839
Autor:
Juliette Piquet, Xavier Toussay, Régine Hepp, Rodrigo Lerchundi, Juliette Le Douce, Émilie Faivre, Elvire Guiot, Gilles Bonvento, Bruno Cauli
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
The impairment of cerebral glucose utilization is an early and predictive biomarker of Alzheimer’s disease (AD) that is likely to contribute to memory and cognition disorders during the progression of the pathology. Yet, the cellular and molecular
Externí odkaz:
https://doaj.org/article/8f41f7c8ee6043e589f5149e248e8f21
Autor:
Maud Martin, Simon Vermeiren, Naguissa Bostaille, Marie Eubelen, Daniel Spitzer, Marjorie Vermeersch, Caterina P. Profaci, Elisa Pozuelo, Xavier Toussay, Joanna Raman-Nair, Patricia Tebabi, Michelle America, Aurélie De Groote, Leslie E. Sanderson, Pauline Cabochette, Raoul F. V. Germano, David Torres, Sébastien Boutry, Alban de Kerchove d’Exaerde, Eric J. Bellefroid, Timothy N. Phoenix, Kavi Devraj, Baptiste Lacoste, Richard Daneman, Stefan Liebner, Benoit Vanhollebeke
Publikováno v:
Science. 375
The blood-brain barrier (BBB) protects the central nervous system (CNS) from harmful blood-borne factors. Although BBB dysfunction is a hallmark of several neurological disorders, therapies to restore BBB function are lacking. An attractive strategy
Autor:
Luciano da Fontoura Costa, Peter Van Dyken, Moises Freitas-Andrade, Christopher J. Bergin, Sylvain Baillet, Yannick D. Benoit, Christopher R.J. Kennedy, Baptiste Lacoste, Youlian Pan, Cesar H. Comin, Julie Ouellette, Ziying Liu, Cameron J Morse, Micaël Carrier, Sonia Leclerc, Marie-Ève Tremblay, Mirabelle Ho, Duncan J. Stewart, Dylan Burger, Melissa Yin, María Lacalle-Aurioles, William L. Stanford, Jean-Francois Thibodeau, Xavier Toussay, Qing Yan Liu
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
While the neuronal underpinnings of autism spectrum disorder (ASD) are being unraveled, vascular contributions to ASD remain elusive. Here, we investigated postnatal cerebrovascular development in the 16p11.2df/+ mouse model of 16p11.2 deletion ASD s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd9e5678d97ad9aa478e986a4be657e
https://doi.org/10.1038/s41593-020-0663-1
https://doi.org/10.1038/s41593-020-0663-1
Autor:
Fumiaki Oka, Homa Sadeghian, Baptiste Lacoste, Cenk Ayata, Tao Qin, Xavier Toussay, Tsubasa Takizawa, David Y. Chung, Roberto Rosa, Chenghua Gu
Publikováno v:
Annals of Neurology. 84:409-423
Objective Cortical spreading depolarizations (CSDs) are intense and ubiquitous depolarization waves relevant for the pathophysiology of migraine and brain injury. CSDs disrupt the blood-brain barrier (BBB), but the mechanisms are unknown. Methods A t
Autor:
Xin-Kang Tong, Amir Shmuel, Claire H. Sandoe, Clotilde Lecrux, Pascal Kropf, Sujaya Neupane, María Lacalle-Aurioles, Edith Hamel, Xavier Toussay
Publikováno v:
The Journal of Neuroscience. 37:1518-1531
Brain imaging techniques that use vascular signals to map changes in neuronal activity rely on the coupling between electrophysiology and hemodynamics, a phenomenon referred to as “neurovascular coupling” (NVC). It is unknown whether this relatio
Publikováno v:
Methods in Molecular Biology ISBN: 9781493991204
A large body of evidence suggests that G protein-coupled receptors (GPCRs) play an important role in the regulation of peripheral vascular reactivity. Meanwhile, the extent of GPCR influence on the regulation of brain vascular reactivity, or cerebral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88fc033daa554486c92167cc372c32e5
https://doi.org/10.1007/978-1-4939-9121-1_22
https://doi.org/10.1007/978-1-4939-9121-1_22
Autor:
Homa, Sadeghian, Baptiste, Lacoste, Tao, Qin, Xavier, Toussay, Roberto, Rosa, Fumiaki, Oka, David Y, Chung, Tsubasa, Takizawa, Chenghua, Gu, Cenk, Ayata
Publikováno v:
Annals of neurology. 84(3)
OBJECTIVE: Cortical spreading depolarizations (CSDs) are intense and ubiquitous depolarization waves relevant for the pathophysiology of migraine and brain injury. CSDs disrupt the blood-brain barrier (BBB), but the mechanisms are unknown. METHODS: A
Autor:
Yoon H. Cho, Xavier Toussay, Marie-Charlotte Boutonnet, Lolita Rotureau, Nathalie Biendon, Nathalie Macrez, Jean-Luc Morel, François-Pierre Legeron
Publikováno v:
Neurobiology of Aging
Neurobiology of Aging, Elsevier, 2017, 58, pp.201-212. ⟨10.1016/j.neurobiolaging.2017.06.015⟩
Neurobiology of Aging, Elsevier, 2017, 58, pp.201-212. ⟨10.1016/j.neurobiolaging.2017.06.015⟩
International audience; Mutations or upregulation in presenilin 1 (PS1) gene are found in familial early-onset Alzheimer's disease or sporadic late-onset Alzheimer's disease, respectively. PS1 has been essentially studied in neurons and its mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc5e52929cd4bbcf81828967dbc8b096
https://hal.archives-ouvertes.fr/hal-03006963/file/toussay-NeurobiolAging2017.pdf
https://hal.archives-ouvertes.fr/hal-03006963/file/toussay-NeurobiolAging2017.pdf
Publikováno v:
The Journal of Neuroscience. 33:3390-3401
The locus coeruleus (LC), the main source of brain noradrenalin (NA), modulates cortical activity, cerebral blood flow (CBF), glucose metabolism, and blood–brain barrier permeability. However, the role of the LC–NA system in the regulation of cor