Data from Preclinical In Vivo Validation of the RAD51 Test for Identification of Homologous Recombination-Deficient Tumors and Patient Stratification

Autor: Violeta Serra, Judith Balmaña, Sara Gutiérrez-Enríquez, Cristina Saura, Mafalda Oliveira, Meritxell Bellet, Rodrigo Dienstmann, Joaquín Arribas, Joaquin Mateo, Ana Oaknin, Teresa Macarulla, Martín Espinosa-Bravo, Vicente Peg, Xavier Serres-Créixams, Orland Díez, Paolo Nuciforo, Robert B. Clarke, Serena Nik-Zainal, Carlos Caldas, Antonino Musolino, Yinghui Zhou, Stefano Cairo, Olivier Déas, Mark J. O'Connor, Josep V. Forment, João M.L. Dias, Andrea Degasperi, Enrique J. Arenas, Jose Jiménez, Judit Grueso, Olga Rodríguez, Marta Guzmán, Guillermo Villacampa, Cristina Viaplana, Alejandro Moles-Fernández, Flaminia Pedretti, Alba Llop-Guevara, Andrea Herencia-Ropero, Benedetta Pellegrino

PARP inhibitors (PARPi) are approved drugs for platinum-sensitive, high-grade serous ovarian cancer (HGSOC) and for breast, prostate, and pancreatic cancers (PaC) harboring genetic alterations impairing homologous recombination repair (HRR). Detectio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c67aeadd6b324b4116978cb0342e8cb5
https://doi.org/10.1158/0008-5472.c.6513876.v1

Supplementary Data from Preclinical In Vivo Validation of the RAD51 Test for Identification of Homologous Recombination-Deficient Tumors and Patient Stratification

Autor: Violeta Serra, Judith Balmaña, Sara Gutiérrez-Enríquez, Cristina Saura, Mafalda Oliveira, Meritxell Bellet, Rodrigo Dienstmann, Joaquín Arribas, Joaquin Mateo, Ana Oaknin, Teresa Macarulla, Martín Espinosa-Bravo, Vicente Peg, Xavier Serres-Créixams, Orland Díez, Paolo Nuciforo, Robert B. Clarke, Serena Nik-Zainal, Carlos Caldas, Antonino Musolino, Yinghui Zhou, Stefano Cairo, Olivier Déas, Mark J. O'Connor, Josep V. Forment, João M.L. Dias, Andrea Degasperi, Enrique J. Arenas, Jose Jiménez, Judit Grueso, Olga Rodríguez, Marta Guzmán, Guillermo Villacampa, Cristina Viaplana, Alejandro Moles-Fernández, Flaminia Pedretti, Alba Llop-Guevara, Andrea Herencia-Ropero, Benedetta Pellegrino

Supplementary Data from Preclinical In Vivo Validation of the RAD51 Test for Identification of Homologous Recombination-Deficient Tumors and Patient Stratification

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531a61a9dca3dc370af15ec53d45e41c
https://doi.org/10.1158/0008-5472.22431354.v1

Active bleeding after kidney biopsy: Successful ultrasound‐guided direct thrombin embolization into the cortical fistula

Autor: Mercedes Perez Lafuente, Xavier Serres-Créixams, Carolina Montealegre, Iciar Uriarte, Jose Miguel Escudero-Fernandez, Mónica Bolufer Cardona

Publikováno v: Journal of Clinical Ultrasound. 49:390-394

A 27-year-old man, previously diagnosed with IgA nephropathy, was referred for native kidney biopsy. After the procedure, the patient presented active bleeding revealed by Doppler and contrast-enhanced ultrasonography at the biopsy site. Successful e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::72e5dfeeea666b8833d48444e565050a
https://doi.org/10.1002/jcu.22939

Preclinical In Vivo Validation of the RAD51 Test for Identification of Homologous Recombination-Deficient Tumors and Patient Stratification

Autor: Benedetta Pellegrino, Andrea Herencia-Ropero, Alba Llop-Guevara, Flaminia Pedretti, Alejandro Moles-Fernández, Cristina Viaplana, Guillermo Villacampa, Marta Guzmán, Olga Rodríguez, Judit Grueso, Jose Jiménez, Enrique J. Arenas, Andrea Degasperi, João M.L. Dias, Josep V. Forment, Mark J. O'Connor, Olivier Déas, Stefano Cairo, Yinghui Zhou, Antonino Musolino, Carlos Caldas, Serena Nik-Zainal, Robert B. Clarke, Paolo Nuciforo, Orland Díez, Xavier Serres-Créixams, Vicente Peg, Martín Espinosa-Bravo, Teresa Macarulla, Ana Oaknin, Joaquin Mateo, Joaquín Arribas, Rodrigo Dienstmann, Meritxell Bellet, Mafalda Oliveira, Cristina Saura, Sara Gutiérrez-Enríquez, Judith Balmaña, Violeta Serra

Publikováno v: Cancer Res

PARP inhibitors (PARPi) are approved drugs for platinum-sensitive, high-grade serous ovarian cancer (HGSOC) and for breast, prostate, and pancreatic cancers (PaC) harboring genetic alterations impairing homologous recombination repair (HRR). Detectio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37dc3338b23d1c6e1fba50dc789bdfe3
https://pubmed.ncbi.nlm.nih.gov/35425960

RAD51 foci as a functional biomarker of homologous recombination repair and PARP inhibitor resistance in germline BRCA-mutated breast cancer

Autor: Ana Vivancos, Petra Kristel, Ginevra Caratu, Isabel T. Rubio, Ana Oaknin, Orland Diez, J. Jimenez, Gemma N Jones, L. de Bustos, J. Cortés, J.C. Barrett, Alejandra Bruna, Urszula M. Polanska, Marta Castroviejo-Bermejo, Beatriz Morancho, Carlos Caldas, Gemma Montalban, Yasir H. Ibrahim, Xavier Serres-Créixams, Sandra Bonache, Judit Grueso, Cristina Cruz, Francesco M. Mancuso, Paolo Nuciforo, Joaquín Arribas, Elaine Cadogan, Mario Guzmán, William J. Howat, Alba Llop-Guevara, Judith Balmaña, Sara Gutiérrez-Enríquez, Roberta Fasani, Brian Dougherty, Jos Jonkers, Zhongwu Lai, J. Baselga, Olga Rodriguez, Mark J. O'Connor, Violeta Serra, Albert Gris-Oliver, Oscar M. Rueda, Cristina Saura

Publikováno v: Annals of Oncology
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

Altres ajuts: European Research Area-NET, Transcan-2 (AC15/00063), Asociación Española Contra el Cáncer (LABAE16020PORTT) i AIOC15152806CRUZ, Generalitat de Catalunya(PERIS, SLT002/16/00477 En el cas dels drets, per a usos comercials contactar amb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cac37072c81f83232b13085f5ef04dc
https://doi.org/10.1093/annonc/mdy099