Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Xavier Monroy"'
Autor:
Alba Vidal-Torres, Begoña Fernández-Pastor, Mónica García, Eva Ayet, Anna Cabot, Javier Burgueño, Xavier Monroy, Bertrand Aubel, Xavier Codony, Luz Romero, Rosalía Pascual, Maria Teresa Serafini, Gregorio Encina, Carmen Almansa, Daniel Zamanillo, Manuel Merlos, José Miguel Vela
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 1, Pp 82-99 (2023)
Opioids are the most effective painkillers, but their benefit-risk balance often hinder their therapeutic use. WLB-73502 is a dual, bispecific compound that binds sigma-1 (S1R) and mu-opioid (MOR) receptors. WLB-73502 is an antagonist at the S1R. It
Externí odkaz:
https://doaj.org/article/5db3e49f2136462cbd27dfe08f2a9b36
Autor:
Antón L. Martínez, José Brea, Eduardo Domínguez, María J. Varela, Catarina Allegue, Raquel Cruz, Xavier Monroy, Manuel Merlos, Javier Burgueño, Ángel Carracedo, María Isabel Loza
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Neuronal differentiation is a complex process through which newborn neurons acquire the morphology of mature neurons and become excitable. We employed a combination of functional and transcriptomic approaches to deconvolute and identify key regulator
Externí odkaz:
https://doaj.org/article/3c8415000e0a492abd7a07ba0e186a39
Autor:
Antón L Martínez, José Brea, Mateo Barro, Xavier Monroy, Manuel Merlos, Javier Burgueño, María Isabel Loza
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248139 (2021)
This work tries to help overcome the lack of relevant translational screening assays, as a limitation for the identification of novel analgesics for neuropathic pain. Hyperexcitability and neurite shortening are common adverse effects of antiviral an
Externí odkaz:
https://doaj.org/article/b44644d883e54db0a1b6b4ab206fa84e
Autor:
Ernesto Xavier Monroy-Vaca, Carlos Manuel Fernández-Andreu, Raúl Díaz-Rodríguez, Gerardo Martínez-Machín, María Teresa Illnait-Zaragozí, Mayda Perurena-Lancha
Publikováno v:
VacciMonitor, Vol 23, Iss 2, Pp 49-56 (2014)
Histoplasmacapsulatum es un hongo endémico de Cuba y el agente causal de la histoplasmosis. Esta micosis se presenta en forma de brotes epidémicos, afecta a las personas, independiente de su estado inmunológico. Su diagnóstico se realiza mediante
Externí odkaz:
https://doaj.org/article/feeaa65f003c44548e31135362f9c45f
Autor:
Antón L, Martínez, José, Brea, Eduardo, Domínguez, María J, Varela, Catarina, Allegue, Raquel, Cruz, Xavier, Monroy, Manuel, Merlos, Javier, Burgueño, Ángel, Carracedo, María Isabel, Loza
Publikováno v:
Frontiers in cellular neuroscience. 16
Neuronal differentiation is a complex process through which newborn neurons acquire the morphology of mature neurons and become excitable. We employed a combination of functional and transcriptomic approaches to deconvolute and identify key regulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b3165ab8605df003317c67f104648251
https://pubmed.ncbi.nlm.nih.gov/35465610
https://pubmed.ncbi.nlm.nih.gov/35465610
Autor:
Raquel Cruz, Catarina Allegue, Xavier Monroy, María J. Varela, Manuel Merlos, María Isabel Loza, Eduardo Domínguez, José Brea, Antón L. Martínez, Javier Burgueño, Marta Cimadevila, Angel Carracedo
Publikováno v:
ACS chemical neuroscience. 12(14)
Neuropathic pain is one of the foremost adverse effects that worsens quality of life for patients undergoing an antiretroviral treatment. Currently, there are no effective analgesics for relieving it; thus, there is an urgent need to develop novel tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737f237a0aeb0f69ac2e9d033f359b48
https://pubmed.ncbi.nlm.nih.gov/34184863
https://pubmed.ncbi.nlm.nih.gov/34184863
Autor:
Xavier Monroy, Antón L. Martínez, José Brea, Javier Burgueño, Manuel Merlos, María Isabel Loza
Publikováno v:
SLAS Discovery. 24:158-168
In this study we developed a new translational phenotypic in vitro model for high-throughput screening (HTS) of novel analgesics for treating neuropathic pain, in order to address the poor translation of traditional recombinant models. The immortaliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8911871c52bc94399963e17ec0f1f6f9
https://doi.org/10.1177/2472555218810323
https://doi.org/10.1177/2472555218810323
Autor:
Javier Burgueño, Manuel Merlos, María Isabel Loza, Antón L. Martínez, Mateo Barro, Xavier Monroy, José Brea
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 3, p e0248139 (2021)
PLoS ONE, Vol 16, Iss 3, p e0248139 (2021)
This work tries to help overcome the lack of relevant translational screening assays, as a limitation for the identification of novel analgesics for neuropathic pain. Hyperexcitability and neurite shortening are common adverse effects of antiviral an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc01b50624bf77e38d92cf85e8fbb8ff
http://europepmc.org/articles/PMC7946280
http://europepmc.org/articles/PMC7946280
Autor:
Raul Durán López, Sidney Xavier Monroy Ochoa, Magdicarla Ercilia De Alba Márquez, Luis Omar Domínguez Palomera, Héctor Macías Reyes
Publikováno v:
ACTA DE OTORRINOLARINGOLOGÍA & CIRUGÍA DE CABEZA Y CUELLO. 43:125-130
Antecedentes: Los abscesos de cuello son procesos de origen infeccioso, que forman una colección de material purulento a través de los planos profundos del cuello e involucran uno o varios de los espacios. La terapia con presión negativa ha sido u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::514166033d70e434b3271c2289f22815
https://doi.org/10.37076/acorl.v43i2.23
https://doi.org/10.37076/acorl.v43i2.23
Autor:
J.L. Diaz, Albert Dordal, Montserrat Contijoch, Xavier Monroy, Raquel Enrech, Jordi Corbera, Ana Montero, Sandra Yeste, Rosa Cuberes, Carmen Almansa
Publikováno v:
MedChemComm. 8:1235-1245
The synthesis of a new series of 4-acylaminopyrazolo[3,4-d]pyrimidines active on the sigma-1 receptor (σ1R) is reported. Compounds were efficiently prepared using a two to three step process starting from commercially available 1H-pyrazolo[3,4-d]pyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff92f9be756859be327b483b32ac61f1
https://doi.org/10.1039/c7md00077d
https://doi.org/10.1039/c7md00077d