Zobrazeno 1 - 10
of 549
pro vyhledávání: '"Xavier Matias-Guiu"'
Autor:
Carlos Casas-Arozamena, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Eva Diaz, Sara S Oltra, Cristian Pablo Moiola, Silvia Cabrera, Alexandra Cortegoso, Teresa Curiel, Alicia Abalo, Mónica Pamies Serrano, Santiago Domingo, Pablo Padilla-Iserte, Marta Arnaez de la Cruz, Alicia Hernández, Virginia García-Pineda, Juan Ruiz-Bañobre, Rafael López, Xavier Matias-Guiu, Eva Colás, Antonio Gil-Moreno, Miguel Abal, Gema Moreno-Bueno, Laura Muinelo-Romay
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-14 (2024)
Abstract Background There has been a rise in endometrial cancer (EC) incidence leading to increased mortality. To counter this trend, improving the stratification of post-surgery recurrence risk and anticipating disease relapse and treatment resistan
Externí odkaz:
https://doaj.org/article/d684ea05bd3b4749890be7772b452478
Autor:
Silvia von der Heyde, Nithya Raman, Nina Gabelia, Xavier Matias-Guiu, Takayuki Yoshino, Yuichiro Tsukada, Gerry Melino, John L. Marshall, Anton Wellstein, Hartmut Juhl, Jobst Landgrebe
Publikováno v:
Cell Death and Disease, Vol 15, Iss 9, Pp 1-12 (2024)
Abstract Tumor tissue collections are used to uncover pathways associated with disease outcomes that can also serve as targets for cancer treatment, ideally by comparing the molecular properties of cancer tissues to matching normal tissues. The quali
Externí odkaz:
https://doaj.org/article/c43b49c6240f42a392649a943ab84cc0
Autor:
Gisela Altés, Anna Olomí, Aida Perramon-Güell, Sara Hernández, Anna Casanovas, Aurora Pérez, Juan Miguel Díaz-Tocados, José Manuel Valdivielso, Cristina Megino, Raúl Navaridas, Xavier Matias-Guiu, Ophir D. Klein, Joaquim Egea, Xavi Dolcet, Andrée Yeramian, Mario Encinas
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Genes of the Sprouty family (Spry1-4) are feedback inhibitors of receptor tyrosine kinases, especially of Ret and the FGF receptors. As such, they play distinct and overlapping roles in embryo morphogenesis and are considered to be tumor sup
Externí odkaz:
https://doaj.org/article/c35f82b053404988a6db6232e37d7598
Ovarian cancer relies on the PDGFRβ–fibronectin axis for tumorsphere formation and metastatic spread
Autor:
Núria Gendrau‐Sanclemente, Agnès Figueras, Kristina Gracova, Álvaro Lahiguera, Elisenda Alsina‐Sanchís, Juan A. Marín‐Jiménez, August Vidal, Xavier Matias‐Guiu, Sergi Fernandez‐Gonzalez, Marc Barahona, Lola Martí, Jordi Ponce, Francesc Viñals
Publikováno v:
Molecular Oncology, Vol 18, Iss 1, Pp 136-155 (2024)
High‐grade serous ovarian cancer (HGSOC) is the deadliest gynecological malignancy. The most common form of metastatic spread of HGSOC is transcoelomic dissemination. In this process, detached cells from the primary tumor aggregate as tumorspheres
Externí odkaz:
https://doaj.org/article/4f70daa21e17417cbad7a4fa4f8ad735
Autor:
Josep León-Mengíbar, Enric Sánchez, Ferrán Herrerías, Mari Cruz De La Fuente, Maite Santamaría, José Manuel Valdivielso, Marcelino Bermúdez-López, Eva Castro, Judit Pallarés, Xavier Matias-Guiu, Felip Vilardell, Assumpta Caixàs, Marta Bueno, Raquel Martí, Albert Lecube
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionNonalcoholic fatty liver disease (NAFLD) affects a quarter of the world’s population and encompasses a spectrum of liver conditions, from non-alcoholic steatohepatitis (NASH) to inflammation and fibrosis. In addition, NAFLD also links t
Externí odkaz:
https://doaj.org/article/eaa2eec326e04ad7b3143538377bfe90
Autor:
Arnau Peñalver-Piñol, Yolanda Benavente, Jon Frias-Gomez, Juan Alguacil, Miguel Santibañez, Manuel Contreras-Llanes, Paula Peremiquel-Trillas, Marta López-Querol, Sonia Paytubi, Beatriz Pelegrina, Irene Onieva, José Manuel Martínez, Sergi Fernandez-Gonzalez, Javier de Francisco, Víctor Caño, Joan Brunet, Marta Pineda, Jordi Ponce, Xavier Matias-Guiu, Francesc Xavier Bosch, Silvia de Sanjosé, Laia Alemany, Laura Costas
Publikováno v:
Environmental Health, Vol 22, Iss 1, Pp 1-11 (2023)
Abstract Background Endometrial cancer is the most common gynaecological tumour in developed countries and disease burden is expected to increase over the years. Identifying modifiable risk factors may help developing strategies to reduce the expecte
Externí odkaz:
https://doaj.org/article/aa75513fe741406d935884d3e9e25065
Autor:
Anna Ruiz-Mitjana, Maria Vidal-Sabanés, Raúl Navaridas, Aida Perramon-Güell, Andree Yeramian, Nathan Nicholson-Sabaté, Joaquim Egea, Mario Encinas, Xavier Matias-Guiu, Xavier Dolcet
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 168, Iss , Pp 115817- (2023)
Metformin is a widespread antidiabetic agent that is commonly used as a treatment against type 2 diabetes mellitus patients. Regarding its therapeutic potential, multiple studies have concluded that Metformin exhibits antineoplastic activity on sever
Externí odkaz:
https://doaj.org/article/7084576a9a2e456c843b6208f523947c
Autor:
Eva Crosas-Molist, Vittoria Graziani, Oscar Maiques, Pahini Pandya, Joanne Monger, Remi Samain, Samantha L. George, Saba Malik, Jerrine Salise, Valle Morales, Adrien Le Guennec, R. Andrew Atkinson, Rosa M. Marti, Xavier Matias-Guiu, Guillaume Charras, Maria R. Conte, Alberto Elosegui-Artola, Mark Holt, Victoria Sanz-Moreno
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Cell migration is crucial for cancer dissemination. We find that AMP-activated protein kinase (AMPK) controls cell migration by acting as an adhesion sensing molecular hub. In 3-dimensional matrices, fast-migrating amoeboid cancer cells exer
Externí odkaz:
https://doaj.org/article/350286488c1e4475afc3dd506fdbc8ec
Autor:
Raúl Navaridas, Maria Vidal‐Sabanés, Anna Ruiz‐Mitjana, Aida Perramon‐Güell, Cristina Megino‐Luque, David Llobet‐Navas, Xavier Matias‐Guiu, Joaquim Egea, Mario Encinas, Lídia Bardia, Julien Colombelli, Xavier Dolcet
Publikováno v:
Cancer Communications, Vol 43, Iss 5, Pp 620-624 (2023)
Externí odkaz:
https://doaj.org/article/07b55548b70041ffb7bc3d9db626bcb2
Autor:
Raúl Navaridas, Maria Vidal‐Sabanés, Anna Ruiz‐Mitjana, Gisela Altés, Aida Perramon‐Güell, Andree Yeramian, Joaquim Egea, Mario Encinas, Sonia Gatius, Xavier Matias‐Guiu, Xavier Dolcet
Publikováno v:
Advanced Science, Vol 10, Iss 32, Pp n/a-n/a (2023)
Abstract Phosphatase and TENsin homolog (Pten) and p53 are two of the most frequently mutated tumor suppressor genes in endometrial cancer. However, the functional consequences and histopathological manifestation of concomitant p53 and Pten loss of f
Externí odkaz:
https://doaj.org/article/a10e9bdc8afb41bba8c8fa70ed603e4f