Zobrazeno 1 - 10
of 463
pro vyhledávání: '"Xavier LeRoy"'
Autor:
Florence Gross, Arturo Mancini, Billy Breton, Hiroyuki Kobayashi, Pedro Henrique Scarpelli Pereira, Christian Le Gouill, Michel Bouvier, Stephan Schann, Xavier Leroy, Laurent Sabbagh
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract Mutations of receptor tyrosine kinases (RTKs) are associated with the development of many cancers by modifying receptor signaling and contributing to drug resistance in clinical settings. We present enhanced bystander bioluminescence resonan
Externí odkaz:
https://doaj.org/article/0cc3d5d503574ee798e91bfae6c8edd3
Autor:
Arnauld Villers, Denis Seguier, Philippe Puech, Georges-Pascal Haber, Mihir M. Desai, Sebastien Crouzet, Xavier Leroy, Julien Labreuche, Inderbir S. Gill, Jonathan Olivier
Publikováno v:
European Urology Open Science, Vol 55, Iss , Pp 11-14 (2023)
Partial prostatectomy has been described as an alternative to focal ablation therapy for the management of localized low- to intermediate-risk prostate cancer. This report aims to describe the long-term outcomes in a series of 28 men (2000–2022) wh
Externí odkaz:
https://doaj.org/article/191fc6b383dd4657a28be07b0502bcb1
Autor:
Thomas Bommelaere, Arnauld Villers, Philippe Puech, Guillaume Ploussard, Julien Labreuche, Elodie Drumez, Xavier Leroy, Jonathan Olivier
Publikováno v:
European Urology Open Science, Vol 41, Iss , Pp 24-34 (2022)
Background: The risk of prostate cancer metastatic is correlated with its volume and grade. These parameters are now best estimated preoperatively with magnetic resonance imaging (MRI) and MRI-guided biopsy. Objective: To estimate the risk of metasta
Externí odkaz:
https://doaj.org/article/bf1a3f47b6484ec184ece2b007f4c38c
Autor:
Ariane Perry, Claire Douillard, Frederic Jonca, Francois Glowacki, Xavier Leroy, Paul Caveriviere, Aurélie Hubert, Philippe Labrune
Publikováno v:
JIMD Reports, Vol 52, Iss 1, Pp 17-22 (2020)
Abstract Glycogen storage disease type Ia (GSD Ia) is a rare metabolic disease due to glucose‐6‐phosphatase deficiency. Chronic kidney disease is a frequent complication that may manifest itself by glomerular lesions and tubular dysfunction from
Externí odkaz:
https://doaj.org/article/3826cc02f85640a09008e0511b007ad8
Autor:
Bochra Tourki, Vasundhara Kain, Amanda B. Pullen, Paul C. Norris, Nirav Patel, Pankaj Arora, Xavier Leroy, Charles N. Serhan, Ganesh V. Halade
Publikováno v:
Molecular Metabolism, Vol 31, Iss , Pp 138-149 (2020)
Objective: Recently, we observed that the specialized proresolving mediator (SPM) entity resolvin D1 activates lipoxin A4/formyl peptide receptor 2 (ALX/FPR2), which facilitates cardiac healing and persistent inflammation is a hallmark of impaired ca
Externí odkaz:
https://doaj.org/article/db743dad70734920abb663bad30b0a4d
Autor:
Charlotte Avet, Arturo Mancini, Billy Breton, Christian Le Gouill, Alexander S Hauser, Claire Normand, Hiroyuki Kobayashi, Florence Gross, Mireille Hogue, Viktoriya Lukasheva, Stéphane St-Onge, Marilyn Carrier, Madeleine Héroux, Sandra Morissette, Eric B Fauman, Jean-Philippe Fortin, Stephan Schann, Xavier Leroy, David E Gloriam, Michel Bouvier
Publikováno v:
eLife, Vol 11 (2022)
The recognition that individual GPCRs can activate multiple signaling pathways has raised the possibility of developing drugs selectively targeting therapeutically relevant ones. This requires tools to determine which G proteins and βarrestins are a
Externí odkaz:
https://doaj.org/article/34e18aa1566b4e768be5932a0e81dff7
Autor:
Anne-Laure Blayo, Laurène Deshons, Alexia Dumont, Christel Franchet, Célia Halter, Ludovic Herbin, Gaël Hommet, Stanislas Mayer, Alban Bessede, Imane Nafia, Marjorie Sidhoum, Xavier Leroy, Stéphan Schann
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/d39d0b87f1fc43e1b9ad9bb03c60bc9a
Autor:
Marion Classe, Hui Yao, Roger Mouawad, Chad J. Creighton, Alice Burgess, Frederick Allanic, Michel Wassef, Xavier Leroy, Benjamin Verillaud, Geoffrey Mortuaire, Franck Bielle, Christophe Le Tourneau, Jean-Emmanuel Kurtz, David Khayat, Xiaoping Su, Gabriel G. Malouf
Publikováno v:
Cell Reports, Vol 25, Iss 3, Pp 811-821.e5 (2018)
Summary: Esthesioneuroblastoma (ENB) is a rare cancer of the olfactory mucosa, with no established molecular stratification to date. We report similarities of ENB with tumors arising in the neural crest and perform integrative analysis of these tumor
Externí odkaz:
https://doaj.org/article/4d98bc81390c4d639fbf7c5b3c275f94
Autor:
Kelly Gaudelot, Jean-Baptiste Gibier, Nicolas Pottier, Brigitte Hémon, Isabelle Van Seuningen, François Glowacki, Xavier Leroy, Christelle Cauffiez, Viviane Gnemmi, Sébastien Aubert, Michaël Perrais
Publikováno v:
Tumor Biology, Vol 39 (2017)
Renal cell carcinoma, the most common neoplasm of adult kidney, accounts for about 3% of adult malignancies and is usually highly resistant to conventional therapy. MicroRNAs are a class of small non-coding RNAs, which have been previously shown to p
Externí odkaz:
https://doaj.org/article/6d8f402c6b994e3da4be2a77a2b99ac2
Autor:
Cynthia Van der Hauwaert, Grégoire Savary, Viviane Gnemmi, François Glowacki, Nicolas Pottier, Audrey Bouillez, Patrice Maboudou, Laurent Zini, Xavier Leroy, Christelle Cauffiez, Michaël Perrais, Sébastien Aubert
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66750 (2013)
Renal proximal tubular epithelial cells play a central role in renal physiology and are among the cell types most sensitive to ischemia and xenobiotic nephrotoxicity. In order to investigate the molecular and cellular mechanisms underlying the pathop
Externí odkaz:
https://doaj.org/article/d149fd66f0e64305ba2306a64bb30c96