Zobrazeno 1 - 10
of 316
pro vyhledávání: '"Xavier León"'
Autor:
Carlos M. Chiesa‐Estomba, Jose A. González‐García, Ekhiñe Larruscain, Jon A. Sistiaga Suarez, Miquel Quer, Xavier León, Paula Martínez‐Ruiz de Apodaca, Celia López‐Mollá, Miguel Mayo‐Yanez, Alfonso Medela
Publikováno v:
World Journal of Otorhinolaryngology-Head and Neck Surgery, Vol 9, Iss 4, Pp 271-279 (2023)
Abstract Introduction Machine learning (ML)‐based facial nerve injury (FNI) forecasting grounded on multicentric data has not been released up to now. Three distinct ML models, random forest (RF), K‐nearest neighbor, and artificial neural network
Externí odkaz:
https://doaj.org/article/b0f26b31d85d42599e1189f377af5d53
Autor:
Estefania Casana, Veronica Jimenez, Claudia Jambrina, Victor Sacristan, Sergio Muñoz, Jordi Rodo, Ignasi Grass, Miquel Garcia, Cristina Mallol, Xavier León, Alba Casellas, Víctor Sánchez, Sylvie Franckhauser, Tura Ferré, Sara Marcó, Fatima Bosch
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 25, Iss , Pp 190-204 (2022)
Type 2 diabetes, insulin resistance, and obesity are strongly associated and are a major health problem worldwide. Obesity largely results from a sustained imbalance between energy intake and expenditure. Therapeutic approaches targeting metabolic ra
Externí odkaz:
https://doaj.org/article/424459a9f476495e9411067950fe1b43
Autor:
Elisa Rioja-Blanco, Irene Arroyo-Solera, Patricia Álamo, Isolda Casanova, Alberto Gallardo, Ugutz Unzueta, Naroa Serna, Laura Sánchez-García, Miquel Quer, Antonio Villaverde, Esther Vázquez, Ramon Mangues, Lorena Alba-Castellón, Xavier León
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 5, Pp 2578-2591 (2022)
Loco-regional recurrences and distant metastases represent the main cause of head and neck squamous cell carcinoma (HNSCC) mortality. The overexpression of chemokine receptor 4 (CXCR4) in HNSCC primary tumors associates with higher risk of developing
Externí odkaz:
https://doaj.org/article/e50be74c1cc148efa52967136404a5f2
CXCR4-targeted nanotoxins induce GSDME-dependent pyroptosis in head and neck squamous cell carcinoma
Autor:
Elisa Rioja-Blanco, Irene Arroyo-Solera, Patricia Álamo, Isolda Casanova, Alberto Gallardo, Ugutz Unzueta, Naroa Serna, Laura Sánchez-García, Miquel Quer, Antonio Villaverde, Esther Vázquez, Xavier León, Lorena Alba-Castellón, Ramon Mangues
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-17 (2022)
Abstract Background Therapy resistance, which leads to the development of loco-regional relapses and distant metastases after treatment, constitutes one of the major problems that head and neck squamous cell carcinoma (HNSCC) patients currently face.
Externí odkaz:
https://doaj.org/article/97f385e1c3e5483b857dd0c10e41d6d9
Autor:
Sara Marcó, Virginia Haurigot, Maria Luisa Jaén, Albert Ribera, Víctor Sánchez, Maria Molas, Miguel Garcia, Xavier León, Carles Roca, Xavier Sánchez, Joan Bertolin, Jennifer Pérez, Gemma Elias, Marc Navarro, Ana Carretero, Martí Pumarola, Anna Andaluz, Yvonne Espada, Sonia Añor, Fatima Bosch
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss , Pp 370-389 (2021)
Delivery of adeno-associated viral vectors (AAVs) to cerebrospinal fluid (CSF) has emerged as a promising approach to achieve widespread transduction of the central nervous system (CNS) and peripheral nervous system (PNS), with direct applicability t
Externí odkaz:
https://doaj.org/article/6c76bc2619ae4a508cc75183a3090a01
Autor:
Joan Bertolin, Víctor Sánchez, Albert Ribera, Maria Luisa Jaén, Miquel Garcia, Anna Pujol, Xavier Sánchez, Sergio Muñoz, Sara Marcó, Jennifer Pérez, Gemma Elias, Xavier León, Carles Roca, Veronica Jimenez, Pedro Otaegui, Francisca Mulero, Marc Navarro, Jesús Ruberte, Fatima Bosch
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Mucopolysaccharidosis type IVA (MPSIVA) is a lysosomal storage disorder causing severe skeletal and non-skeletal alterations in patients. Here, the authors generate a MPSIVA rat model that mimics the disabling human pathology and develop an AAV9-Galn
Externí odkaz:
https://doaj.org/article/4ba8f5aa92cf4b558796ff21512a7699
Publikováno v:
La Granja: Revista de Ciencias de la Vida, Vol 35, Iss 1 (2021)
Los espacios de comercialización agroecológica se han expandido en el país, debido a la importancia que los productores y consumidores le están dando al origen y la forma de producción de los alimentos. Sin embargo, poco se ha estudiado sobre la
Externí odkaz:
https://doaj.org/article/9fad783a5ce348d1b05401b3c2c87539
Autor:
Miguel Mayo-Yáñez, José M. Palacios-García, Christian Calvo-Henríquez, Tareck Ayad, Nadim Saydy, Xavier León, Pablo Parente, Carlos Miguel Chiesa-Estomba, Jérôme R. Lechien
Publikováno v:
International Archives of Otorhinolaryngology, Vol 25, Iss 04, Pp e610-e615 (2021)
Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has represented a major challenge for healthcare systems worldwide, changing the habits of physicians. A reorganization of healthcare activity has been necessary, limiting surg
Externí odkaz:
https://doaj.org/article/a67a87f3dcf64c2c9bf1c23288eb7825
Autor:
Anna Sumarroca, Elena Rodríguez-Bauzà, Joan Lop-Gros, Jacinto García, Montserrat López, Miquel Quer, Xavier León
Publikováno v:
Brazilian Journal of Otorhinolaryngology, Vol 85, Iss 3, Pp 351-356 (2019)
Introduction: The pectoralis major flap is a reconstructive option to consider in the treatment of pharyngocutaneous fistula after a total laryngectomy. There are not large studies assessing variables related to pharyngocutaneous fistula recurrence a
Externí odkaz:
https://doaj.org/article/9a0e526151234e689ff34c0e3a407cf1
Autor:
Carla Meler-Claramonte, Francesc Xavier Avilés-Jurado, Isabel Vilaseca, Ximena Terra, Paloma Bragado, Gemma Fuster, Xavier León Vintró, Mercedes Camacho
Publikováno v:
Cancers, Vol 14, Iss 9, p 2259 (2022)
The expression of the semaphorin-3F (SEMA3F) and neuropilin-2 (NRP2) is involved in the regulation of lymphangiogenesis. The present study analyzes the relationship between the transcriptional expression of the SEMA3F-NRP2 genes and the presence of o
Externí odkaz:
https://doaj.org/article/cab473c68ee14e7d953e64b896322776