Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Xavier J. H. Pepin"'
Autor:
Xavier J. H. Pepin, Scott M. Hynes, Hamim Zahir, Deborah Walker, Lois Q. Semmens, Sandra Suarez‐Sharp
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 10, Pp 1771-1783 (2024)
Abstract Omaveloxolone is a nuclear factor (erythroid‐derived 2)‐like 2 activator approved in the United States and the European Union for the treatment of patients with Friedreich ataxia aged ≥16 years, with a recommended dosage of 150 mg oral
Externí odkaz:
https://doaj.org/article/d460f6850b8b4da5a5d2f5e21b780d1f
Publikováno v:
Pharmaceutical research.
A physiologically based biopharmaceutics model (PBBM) was developed to mechanistically investigate the effect of formulation and food on selumetinib pharmacokinetics.Selumetinib is presented as a hydrogen sulfate salt, and in vitro and in vivo data w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5d565d85c197740305c94de968dd9b
https://pubmed.ncbi.nlm.nih.gov/36002614
https://pubmed.ncbi.nlm.nih.gov/36002614
Publikováno v:
Pharmaceutical research. 39(8)
The use of physiologically based pharmacokinetic (PBPK) modeling to support the drug product quality attributes, also known as physiologically based biopharmaceutics modeling (PBBM) is an evolving field and the interest in using PBBM is increasing. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebb82b24a66008a3d4024c1f3d9adeb6
https://pubmed.ncbi.nlm.nih.gov/35585448
https://pubmed.ncbi.nlm.nih.gov/35585448