Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Xavier Guillonneau"'
Autor:
Christophe Roubeix, Caroline Nous, Sébastien Augustin, Kaitryn E. Ronning, Thibaud Mathis, Frédéric Blond, Pauline Lagouge-Roussey, Sergio Crespo-Garcia, Patrick M. Sullivan, Emmanuel L. Gautier, Nadine Reichhart, José-Alain Sahel, Marie E. Burns, Michel Paques, Torben Lykke Sørensen, Olaf Strauss, Xavier Guillonneau, Cécile Delarasse, Florian Sennlaub
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Age-related macular degeneration (AMD) is invariably associated with the chronic accumulation of activated mononuclear phagocytes in the subretinal space. The mononuclear phagocytes are composed of microglial cells but also of monocyte-deriv
Externí odkaz:
https://doaj.org/article/15a2fe8398d24307833b4ae362a8cd9b
Autor:
Sebastien Augustin, Marion Lam, Sophie Lavalette, Anna Verschueren, Frédéric Blond, Valérie Forster, Lauriane Przegralek, Zhiguo He, Daniel Lewandowski, Alexis-Pierre Bemelmans, Serge Picaud, José-Alain Sahel, Thibaud Mathis, Michel Paques, Gilles Thuret, Xavier Guillonneau, Cécile Delarasse, Florian Sennlaub
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Retinal melanosome/melanolipofuscin-containing cells (MCCs), clinically visible as hyperreflective foci (HRF) and a highly predictive imaging biomarker for the progression of age-related macular degeneration (AMD), are widely believed to be
Externí odkaz:
https://doaj.org/article/36478ff34584497caa06ecb1e684bdde
Autor:
Guillaume Blot, Rémi Karadayi, Lauriane Przegralek, Thérèse-Marie Sartoris, Hugo Charles-Messance, Sébastien Augustin, Pierre Negrier, Frédéric Blond, Frida Paulina Muñiz-Ruvalcaba, David Rivera-de la Parra, Lucile Vignaud, Aude Couturier, José-Alain Sahel, Niyazi Acar, Aida Jimenez-Corona, Cécile Delarasse, Yonathan Garfias, Florian Sennlaub, Xavier Guillonneau
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 19 (2023)
Type 2 diabetes mellitus (T2DM), characterized by hyperglycemia and dyslipidemia, leads to nonproliferative diabetic retinopathy (NPDR). NPDR is associated with blood-retina barrier disruption, plasma exudates, microvascular degeneration, elevated in
Externí odkaz:
https://doaj.org/article/a428d0dd6e824e1eaa04dc9d73afec22
Efficacy and Safety of Low-Intensity Pulsed Ultrasound-Induced Blood–Retinal Barrier Opening in Mice
Autor:
Alexandre Bourdin, Manon Ortoli, Remi Karadayi, Lauriane Przegralek, Florian Sennlaub, Bahram Bodaghi, Xavier Guillonneau, Alexandre Carpentier, Sara Touhami
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1896 (2023)
Systemic drugs can treat various retinal pathologies such as retinal cancers; however, their ocular diffusion may be limited by the blood–retina barrier (BRB). Sonication corresponds to the use of ultrasound (US) to increase the permeability of cel
Externí odkaz:
https://doaj.org/article/a98f9fdf1c9949729a1c8b827ac1e1ea
Autor:
Kaitryn E. Ronning, Paul-Alexandre Déchelle-Marquet, Yueshen Che, Xavier Guillonneau, Florian Sennlaub, Cécile Delarasse
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11747 (2023)
Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by impaired episodic memory and two pathological lesions: amyloid plaques and neurofibrillary tangles. In AD, damaged neurons and the accumulation of amyloid β (Aβ)
Externí odkaz:
https://doaj.org/article/2e31027e27514b4cb9f4347208ce67b0
Autor:
Jean-Baptiste Conart, Guillaume Blot, Sébastien Augustin, Géraldine Millet-Puel, Christophe Roubeix, Fanny Beguier, Hugo Charles-Messance, Sara Touhami, José-Alain Sahel, Jean-Paul Berrod, Thierry Léveillard, Xavier Guillonneau, Cécile Delarasse, Florian Sennlaub
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-15 (2020)
Abstract Background Rhegmatogenous retinal detachment (RD) involving the macula is a major cause of visual impairment despite high surgical success rate, mainly because of cone death. RD causes the infiltration of activated immune cells, but it is no
Externí odkaz:
https://doaj.org/article/d3b70a8884584bef8296201e33f43b57
Autor:
Hugo Charles-Messance, Guillaume Blot, Aude Couturier, Lucile Vignaud, Sara Touhami, Fanny Beguier, Lourdes Siqueiros, Valérie Forster, Nour Barmo, Sébastien Augustin, Serge Picaud, José-Alain Sahel, Alvaro Rendon, Antje Grosche, Ramin Tadayoni, Florian Sennlaub, Xavier Guillonneau
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-12 (2020)
Abstract Background Age-related macular degeneration is characterized by the accumulation of subretinal macrophages and the degeneration of cones, but mainly of rods. We have previously shown that Mononuclear Phagocytes-derived IL-1β induces rod pho
Externí odkaz:
https://doaj.org/article/ba2b21cbea714d25a985d57a5761ff73
Autor:
Christophe Roubeix, Elisa Dominguez, William Raoul, Xavier Guillonneau, Michel Paques, José-Alain Sahel, Florian Sennlaub
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-9 (2019)
Abstract Background To decipher the role of monocyte-derived macrophages (Mφs) in vascular remodeling of the occluded vein following experimental branch retinal vein occlusion (BRVO). Methods The inflammation induced by laser-induced BRVO on mice re
Externí odkaz:
https://doaj.org/article/e9efdb633bee4049b5892349a79bb062
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100281- (2021)
Summary: The classical aortic ring model is well suited for deciphering pro-angiogenic processes. Here, we propose simple modifications of the standard protocol to study various anti-angiogenic processes from growth arrest to capillary degeneration.
Externí odkaz:
https://doaj.org/article/c72549455954480b80690ee1ce789930
Autor:
Sophie Lavalette, Jean-Baptiste Conart, Sara Touhami, Christophe Roubeix, Marianne Houssier, Sébastien Augustin, William Raoul, Christophe Combadière, Maria Febbraio, Huy Ong, Sylvain Chemtob, José-Alain Sahel, Cécile Delarasse, Xavier Guillonneau, Florian Sennlaub
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Background: CD36, a member of the class B scavenger receptor family, participates in Toll-like receptor signaling on mononuclear phagocytes (MP) and can promote sterile pathogenic inflammation. We here analyzed the effect of CD36 deficiency on retina
Externí odkaz:
https://doaj.org/article/64e88b19444c4408b242d6d725cc1cba