Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Xavier Gromada"'
Autor:
Clément Philippe Delannoy, Egon Heuson, Adrien Herledan, Frederik Oger, Bryan Thiroux, Mickaël Chevalier, Xavier Gromada, Laure Rolland, Philippe Froguel, Benoit Deprez, Sébastien Paul, Jean-Sébastien Annicotte
Publikováno v:
Cells, Vol 12, Iss 6, p 849 (2023)
Type 2 diabetes (T2D) is a metabolic disorder characterized by loss of pancreatic β-cell function, decreased insulin secretion and increased insulin resistance, that affects more than 537 million people worldwide. Although several treatments are pro
Externí odkaz:
https://doaj.org/article/8713886262774b1a8af08dcc746eafc0
Autor:
Konstantina Kourmentza, Xavier Gromada, Nicholas Michael, Charlotte Degraeve, Gaetan Vanier, Rozenn Ravallec, Francois Coutte, Kimon Andreas Karatzas, Paula Jauregi
Publikováno v:
Frontiers in Microbiology, Vol 11 (2021)
Lipopeptide biosurfactants produced by Bacillus sp. were assessed regarding their antimicrobial activity against foodborne pathogenic and food spoilage microorganisms. Both Gram-positive and Gram-negative bacteria were found not to be susceptible to
Externí odkaz:
https://doaj.org/article/46f954eb513b4d028ab39719cfce8b77
Autor:
Florine Bornaque, Clément Philippe Delannoy, Emilie Courty, Nabil Rabhi, Charlène Carney, Laure Rolland, Maeva Moreno, Xavier Gromada, Cyril Bourouh, Pauline Petit, Emmanuelle Durand, François Pattou, Julie Kerr-Conte, Philippe Froguel, Amélie Bonnefond, Frédérik Oger, Jean-Sébastien Annicotte
Publikováno v:
Cells, Vol 11, Iss 2, p 291 (2022)
Type 2 diabetes is characterized by chronic hyperglycemia associated with impaired insulin action and secretion. Although the heritability of type 2 diabetes is high, the environment, including blood components, could play a major role in the develop
Externí odkaz:
https://doaj.org/article/6966ecd7b0ea46b7922fa05d22b50b8e
Autor:
Nabil Rabhi, Sarah Anissa Hannou, Xavier Gromada, Elisabet Salas, Xi Yao, Frédérik Oger, Charlène Carney, Isabel C. Lopez-Mejia, Emmanuelle Durand, Iandry Rabearivelo, Amélie Bonnefond, Emilie Caron, Lluis Fajas, Christian Dani, Philippe Froguel, Jean-Sébastien Annicotte
Publikováno v:
Molecular Metabolism, Vol 8, Iss , Pp 65-76 (2018)
Objectives: Genome-wide association studies have reported that DNA polymorphisms at the CDKN2A locus modulate fasting glucose in human and contribute to type 2 diabetes (T2D) risk. Yet the causal relationship between this gene and defective energy ho
Externí odkaz:
https://doaj.org/article/b78363c754f44dd2856be9f0727becc3
Autor:
Nabil Rabhi, Pierre-Damien Denechaud, Xavier Gromada, Sarah Anissa Hannou, Hongbo Zhang, Talha Rashid, Elisabet Salas, Emmanuelle Durand, Olivier Sand, Amélie Bonnefond, Loic Yengo, Carine Chavey, Caroline Bonner, Julie Kerr-Conte, Amar Abderrahmani, Johan Auwerx, Lluis Fajas, Philippe Froguel, Jean-Sébastien Annicotte
Publikováno v:
Cell Reports, Vol 15, Iss 5, Pp 1051-1061 (2016)
The endoplasmic reticulum (ER) unfolded protein response (UPRer) pathway plays an important role in helping pancreatic β cells to adapt their cellular responses to environmental cues and metabolic stress. Although altered UPRer gene expression appea
Externí odkaz:
https://doaj.org/article/eb7c370bd74d4911868e64387fc60856
Autor:
Jean-Sébastien Annicotte, Patrick Collombat, Amélie Bonnefond, Benoit Pourcet, Philippe Froguel, François Pattou, Julie Kerr-Conte, Lluis Fajas, Patrick Meffre, Zohra Benfodda, Pierre-Damien Denechaud, Sarah Anissa Hannou, Etienne Blanc, Mehdi Derhourhi, Lionel Berberian, Souhila Amanzougarene, Emmanuelle Durand, Nabil Rabhi, Charlène Carney, Maeva Moreno, Xavier Gromada, Laure Rolland, Emilie Courty, Marika Elsa Friano, Cyril Bourouh, Frédérik Oger
The loss of pancreatic β-cell identity emerges as an important feature of type 2 diabetes development, but the molecular mechanisms are still elusive. Here, we explore the cell-autonomous role of the cell cycle regulator and transcription factor E2F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a8b941ef57b5273737f441d7144efa3
https://doi.org/10.2337/figshare.22906517.v1
https://doi.org/10.2337/figshare.22906517.v1
Autor:
Frédérik Oger, Cyril Bourouh, Marika Elsa Friano, Emilie Courty, Laure Rolland, Xavier Gromada, Maeva Moreno, Charlène Carney, Nabil Rabhi, Emmanuelle Durand, Souhila Amanzougarene, Lionel Berberian, Mehdi Derhourhi, Etienne Blanc, Sarah Anissa Hannou, Pierre-Damien Denechaud, Zohra Benfodda, Patrick Meffre, Lluis Fajas, Julie Kerr-Conte, François Pattou, Philippe Froguel, Benoit Pourcet, Amélie Bonnefond, Patrick Collombat, Jean-Sébastien Annicotte
Publikováno v:
Diabetes.
The loss of pancreatic β-cell identity emerges as an important feature of type 2 diabetes development, but the molecular mechanisms are still elusive. Here, we explore the cellautonomous role of the cell cycle regulator and transcription factor E2F1
Autor:
Cyril Bourouh, Emilie Courty, Laure Rolland, Gianni Pasquetti, Xavier Gromada, Nabil Rabhi, Charlène Carney, Maeva Moreno, Raphaël Boutry, Emilie Caron, Zohra Benfodda, Patrick Meffre, Julie Kerr-Conte, François Pattou, Philippe Froguel, Amélie Bonnefond, Frédérik Oger, Jean-Sébastien Annicotte
Publikováno v:
Cell Reports
Cell Reports, 2022, 40 (6), pp.111170. ⟨10.1016/j.celrep.2022.111170⟩
Cell Reports, 2022, 40 (6), pp.111170. ⟨10.1016/j.celrep.2022.111170⟩
The glucagon-like peptide 1 (Glp-1) has emerged as a hormone with broad pharmacological potential in type 2 diabetes (T2D) treatment, notably by improving β cell functions. The cell-cycle regulator and transcription factor E2f1 is involved in glucos
Autor:
François Pattou, Patrick Meffre, Zohra Benfodda, Frédérik Oger, Gianni Pasquetti, Xavier Gromada, Julie Kerr-Conte, Amélie Bonnefond, Emilie Courty, Charlène Carney, Laure Rolland, Cyril Bourouh, Philippe Froguel, Emilie Caron, Jean-Sébastien Annicotte, Maeva Moreno, Raphael Boutry, Nabil Rabhi
Compromised β-cell function contributes to type 2 diabetes (T2D) development. The glucagon like peptide 1 (Glp-1) has emerged as a hormone with broad pharmacological potential toward T2D treatment, notably by improving β-cell functions. Recent data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88adbc71ac2fb89a3f521268dc796885
https://doi.org/10.1101/2021.04.16.440172
https://doi.org/10.1101/2021.04.16.440172
Autor:
Cyril Bourouh, Emilie Courty, Gianni Pasquetti, Xavier Gromada, Nabil Rabhi, Charlene Carney, Maeva Moreno, Raphael Boutry, Laure Rolland, Emilie Caron, Zohra Benfodda, Patrick Meffre, Julie Kerr-Conte, Francois Pattou, Phillipe Froguel, Amélie Bonnefond, Frederik Oger, Jean-Sebastien Annicotte
Publikováno v:
SSRN Electronic Journal.