Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Xavier Gasull"'
A photoswitchable inhibitor of TREK channels controls pain in wild-type intact freely moving animals
Autor:
Arnaud Landra-Willm, Ameya Karapurkar, Alexia Duveau, Anne Amandine Chassot, Lucille Esnault, Gerard Callejo, Marion Bied, Stephanie Häfner, Florian Lesage, Brigitte Wdziekonski, Anne Baron, Pascal Fossat, Laurent Marsollier, Xavier Gasull, Eric Boué-Grabot, Michael A. Kienzler, Guillaume Sandoz
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Research on pain often relies on animals, and there is always a need for more precise and more ethical tools. Here, authors present a light-activatable molecule that induces pain in freely moving animal models in a reversible, non-invasive, and spati
Externí odkaz:
https://doaj.org/article/4a75ffe8336b4cd5967121ece0b3ada7
Autor:
Júlia Llimós-Aubach, Alba Andrés-Bilbé, Aida Castellanos, Anna Pujol, Helena Lluís, Núria Comes, Gerard Callejo, Xavier Gasull
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S683- (2023)
Externí odkaz:
https://doaj.org/article/2819931b162f42fd86fee6aeb6333f3b
Autor:
Aida Castellanos, Javier Picañol, Esther Gratacòs-Batlle, Maud Rimbaut, Nuria Casals, Xavier Gasull, Juan D. Navarro-López, Lydia Jiménez-Díaz, David Soto
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S708- (2023)
Externí odkaz:
https://doaj.org/article/73c9bf1f51344b3eacbca3a5f0ba1279
Autor:
Helena Lluís, Marija Radosevic, Júlia Llimós-Aubach, Gerard Callejo, Núria Comes, Xavier Gasull
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S316-S317 (2023)
Externí odkaz:
https://doaj.org/article/432826ff81224817b32205fdeca2daad
Autor:
Alicia Jurado, Anna Ulldemolins, Helena Lluís, Xavier Gasull, Núria Gavara, Raimon Sunyer, Jorge Otero, David Gozal, Isaac Almendros, Ramon Farré
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
Background: Patients with obstructive sleep apnea (OSA) experience recurrent hypoxemic events with a frequency sometimes exceeding 60 events/h. These episodic events induce downstream transient hypoxia in the parenchymal tissue of all organs, thereby
Externí odkaz:
https://doaj.org/article/00a9a42a0e234a6eb145cf7d212b8422
Autor:
Elena Millá, Néstor Ventura-Abreu, Cristina Vendrell, Maria Jesús Muniesa, Marta Pazos, Xavier Gasull, Núria Comes
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 11949 (2023)
The early failure of glaucoma surgery is mainly caused by over-fibrosis at the subconjunctival space, causing obliteration of the filtration bleb. Because fibrosis has a suspected basis of genetic predisposition, we have undertaken a prospective stud
Externí odkaz:
https://doaj.org/article/7debb006cb634d5fbb14f61ad6d91194
Autor:
Minh Ngoc Tran, Timea Medveczki, Balazs Besztercei, Gyorgy Torok, Attila J. Szabo, Xavier Gasull, Illes Kovacs, Andrea Fekete, Judit Hodrea
Publikováno v:
Life, Vol 13, Iss 7, p 1581 (2023)
The trabecular meshwork (TM) route is the principal outflow egress of the aqueous humor. Actin cytoskeletal remodeling in the TM and extracellular matrix (ECM) deposition increase TM stiffness, outflow resistance, and elevate intraocular pressure (IO
Externí odkaz:
https://doaj.org/article/f96803de5c6442e6ba0c523f26f6b606
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Protons reaching the eyeball from exogenous acidic substances or released from damaged cells during inflammation, immune cells, after tissue injury or during chronic ophthalmic conditions, activate or modulate ion channels present in sensory nerve fi
Externí odkaz:
https://doaj.org/article/194d59a3fbab47469fdef6b36a01080b
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Volume-regulated anion channel (VRAC), constituted by leucine-rich repeat-containing 8 (LRRC8) heteromers, is crucial for volume homeostasis in vertebrate cells. This widely expressed channel has been associated with membrane potential modulation, pr
Externí odkaz:
https://doaj.org/article/18adb44fc0644d9bb3d7d8bd2aa5d2c7
Autor:
Xabier Elorza-Vidal, Sònia Sirisi, Héctor Gaitán-Peñas, Carla Pérez-Rius, Marta Alonso-Gardón, Mercedes Armand-Ugón, Angela Lanciotti, Maria Stefania Brignone, Esther Prat, Virginia Nunes, Elena Ambrosini, Xavier Gasull, Raúl Estévez
Publikováno v:
Neurobiology of Disease, Vol 119, Iss , Pp 88-99 (2018)
Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare type of leukodystrophy caused by mutations in either MLC1 or GLIALCAM genes. Previous work indicated that chloride currents mediated by the volume-regulated anion channel (VRA
Externí odkaz:
https://doaj.org/article/07016d228ca04064967df3945f315c92