Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Xavier Gaeta"'
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169237 (2017)
The let-7 family of miRNAs have been shown to control developmental timing in organisms from C. elegans to humans; their function in several essential cell processes throughout development is also well conserved. Numerous studies have defined several
Externí odkaz:
https://doaj.org/article/b868595190c548189cddd904b141cc7a
Autor:
Yuan Xie, Jin Zhang, Ying Lin, Xavier Gaeta, Xiangzhi Meng, Dona R.R. Wisidagama, Jessica Cinkornpumin, Carla M. Koehler, Cindy S. Malone, Michael A. Teitell, William E. Lowry
Publikováno v:
Stem Cell Reports, Vol 3, Iss 5, Pp 743-757 (2014)
Hypoxia augments human embryonic stem cell (hESC) self-renewal via hypoxia-inducible factor 2α-activated OCT4 transcription. Hypoxia also increases the efficiency of reprogramming differentiated cells to a pluripotent-like state. Combined, these fin
Externí odkaz:
https://doaj.org/article/f150f12417194f82aa00d733a5ab8722
Autor:
Rachel Kim, Wen Gu, Alanna B. Chan, Kathrin Plath, Xavier Gaeta, Candice S. Hong, William E. Lowry, Heather R. Christofk, Anna Sahakyan, Daniel Braas
Publikováno v:
Cell Stem Cell. 19:476-490
The rate of glycolytic metabolism changes during differentiation of human embryonic stem cells (hESCs) and reprogramming of somatic cells to pluripotency. However, the functional contribution of glycolytic metabolism to the pluripotent state is uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf58bf10ba0b9cb645e74cf586718d8
https://doi.org/10.1016/j.stem.2016.08.008
https://doi.org/10.1016/j.stem.2016.08.008
Autor:
Michael E. Jung, Richard I. Gregory, David N. Chan, Jessica K Cinkornpumin, Xavier Gaeta, Liem H. Nguyen, William E. Lowry, Liu Xiaoguang, A. Liu, Hao Zhu, Syh-Jae Lin, Martina Roos, John P. Chute
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
The let-7 family of miRNAs has been shown to be crucial in many aspects of biology, from the regulation of developmental timing to cancer. The available methods to regulate this family of miRNAs have so far been mostly genetic and therefore not easil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1896bea7fa77b92a7045cbbab4aa0793
http://europepmc.org/articles/PMC5698460
http://europepmc.org/articles/PMC5698460
Autor:
Xavier Gaeta, Arjun V Pendharkar, Nancy Wang, Raphael Guzman, Robert H. Andres, Jaya K. Nathan, Gary K. Steinberg, Star W. Lee, Raymond Choi, Theo D. Palmer, Joshua Y. Chua
Publikováno v:
Stroke. 42:2923-2931
Background and Purpose— The inflammatory response is a critical component of ischemic stroke. In addition to its physiological role, the mechanisms behind transendothelial recruitment of immune cells also offer a unique therapeutic opportunity for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2a3be63cf7c75e1ee7fe24e24e90fc6
https://doi.org/10.1161/strokeaha.110.606368
https://doi.org/10.1161/strokeaha.110.606368
Autor:
Raphael Guzman, Michael E. Moseley, Joshua Y. Chua, Xavier Gaeta, Raymond Choi, Robert H. Andres, Nancy Wang, Jian Zhang, Arjun V Pendharkar
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 31:1263-1271
Intra-arterial (IA) injection represents an experimental avenue for minimally invasive delivery of stem cells to the injured brain. It has however been reported that IA injection of stem cells carries the risk of reduction in cerebral blood flow (CBF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb254247d83813c39a01379b697af2bf
https://doi.org/10.1038/jcbfm.2010.213
https://doi.org/10.1038/jcbfm.2010.213
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169237 (2017)
PLoS ONE
PLoS ONE
The let-7 family of miRNAs have been shown to control developmental timing in organisms from C. elegans to humans; their function in several essential cell processes throughout development is also well conserved. Numerous studies have defined several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e65d56e952403b0d08cb63fbdcede8f9
https://doi.org/10.1371/journal.pone.0169237
https://doi.org/10.1371/journal.pone.0169237
Autor:
Xiangzhi Meng, Xavier Gaeta, Ying Lin, Jessica K Cinkornpumin, Carla M. Koehler, Michael A. Teitell, Cindy S. Malone, William E. Lowry, Yuan Xie, Jin Zhang, Dona R.R. Wisidagama
Publikováno v:
Stem cell reports, vol 3, iss 5
Stem Cell Reports
Stem Cell Reports, Vol 3, Iss 5, Pp 743-757 (2014)
Stem Cell Reports
Stem Cell Reports, Vol 3, Iss 5, Pp 743-757 (2014)
Summary Hypoxia augments human embryonic stem cell (hESC) self-renewal via hypoxia-inducible factor 2α-activated OCT4 transcription. Hypoxia also increases the efficiency of reprogramming differentiated cells to a pluripotent-like state. Combined, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd944e73fbb9e7fda3f55331ca6b820d
https://escholarship.org/uc/item/7j0665pp
https://escholarship.org/uc/item/7j0665pp
Autor:
Pendharkar, Arjun V., Chua, Josh Y., Andres, Robert H., Wang, Nancy, Xavier Gaeta, Hui Wang, Abhijit De, Choi, Raymond, Shawn Chen, Rutt, Brian K., Gambhir, Sanjiv S., Guzman, Raphael
Publikováno v:
Stroke (00392499); Sep2010, Vol. 41 Issue 9, p2064-2070, 7p
Autor:
A. Solomon, Xavier Gaeta, Igal Germanguz, William E. Lowry, Jennifer Listgarten, Jessica K Cinkornpumin
Publikováno v:
Stem Cell Research, Vol 16, Iss 3, Pp 712-724 (2016)
Using a compendium of cell-state-specific gene expression data, we identified genes that uniquely define cell states, including those thought to represent various developmental stages. Our analysis sheds light on human cell fate through the identific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e012dc286fd27e5ec4f132b51497c3fc