Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Xavier Dagenais-Lussier"'
Autor:
Liseth Carmona-Pérez, Xavier Dagenais-Lussier, Linh T. Mai, Tanja Stögerer, Sharada Swaminathan, Stéphane Isnard, Matthew R. Rice, Betsy J. Barnes, Jean-Pierre Routy, Julien van Grevenynghe, Simona Stäger
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
HIV-1 infection is characterized by inflammation and a progressive decline in CD4+ T cell count. Despite treatment with antiretroviral therapy (ART), the majority of people living with HIV (PLWH) maintain residual levels of inflammation, a low degree
Externí odkaz:
https://doaj.org/article/f2823c61a0e14a9e9f33b2d74c271aa6
Autor:
Xavier Dagenais-Lussier, Hamza Loucif, Hugo Cadorel, Juliette Blumberger, Stéphane Isnard, Mariana Gé Bego, Éric A Cohen, Jean-Pierre Routy, Julien van Grevenynghe, Montreal Primary Infection Study Group
Publikováno v:
PLoS Pathogens, Vol 15, Iss 10, p e1008060 (2019)
The loss of Memory CD4 T-cells (Mem) is a major hallmark of HIV-1 immuno-pathogenesis and occurs early during the first months of primary infection. A lot of effort has been put into understanding the molecular mechanisms behind this loss, yet they s
Externí odkaz:
https://doaj.org/article/6a88ccc083504e91a9ce6a927e3cea70
Autor:
Cherifa Beji, Hamza Loucif, Roman Telittchenko, David Olagnier, Xavier Dagenais-Lussier, Julien van Grevenynghe
Publikováno v:
Viruses, Vol 12, Iss 8, p 875 (2020)
This review examines the impact of cannabinoids on viral infections, as well as its effects on the mitochondria of the nervous and immune system. The paper conveys information about the beneficial and negative impacts of cannabinoids on viral infecti
Externí odkaz:
https://doaj.org/article/e0fb76bcd12e405cbeabd6772aac6c49
Autor:
Xavier Dagenais-Lussier, Hamza Loucif, Armstrong Murira, Xavier Laulhé, Simona Stäger, Alain Lamarre, Julien van Grevenynghe
Publikováno v:
Viruses, Vol 10, Iss 1, p 12 (2017)
Type I interferons (IFN-I) are one of the primary immune defenses against viruses. Similar to all other molecular mechanisms that are central to eliciting protective immune responses, IFN-I expression is subject to homeostatic controls that regulate
Externí odkaz:
https://doaj.org/article/2ae1c49e638a4a17a36db22aefca482d
Autor:
Liseth Carmona-Perez, Xavier Dagenais-Lussier, Linh Thuy Mai, Tanja Stögerer, Sharada Swaminathan, Stephane Isnard, Matthew R. Rice, Betsy J. Barnes, Jean Pierre Routy, Julien van Grevenynghe, Simona Stager
Publikováno v:
JCI Insight.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::684244ef382cee574f01968b62d23996
https://doi.org/10.1172/jci.insight.167329
https://doi.org/10.1172/jci.insight.167329
Autor:
Xavier Dagenais-Lussier, Jean-Pierre Routy, Roman Tellitchenko, David Olagnier, Léna Cassin, Cherifa Beji, Julien van Grevenynghe, Hani Jrade, Hamza Loucif
Publikováno v:
Autophagy
Loucif, H, Dagenais-Lussier, X, Beji, C, Cassin, L, Jrade, H, Tellitchenko, R, Routy, J-P, Olagnier, D & van Grevenynghe, J 2021, ' Lipophagy confers a key metabolic advantage that ensures protective CD8A T-cell responses against HIV-1 ', Autophagy, vol. 17, no. 11, pp. 3408-3423 . https://doi.org/10.1080/15548627.2021.1874134
Loucif, H, Dagenais-Lussier, X, Beji, C, Cassin, L, Jrade, H, Tellitchenko, R, Routy, J-P, Olagnier, D & van Grevenynghe, J 2021, ' Lipophagy confers a key metabolic advantage that ensures protective CD8A T-cell responses against HIV-1 ', Autophagy, vol. 17, no. 11, pp. 3408-3423 . https://doi.org/10.1080/15548627.2021.1874134
Although macroautophagy/autophagy has been proposed as a critical defense mechanism against HIV-1 by targeting viral components for degradation, its contribution as a catabolic process in providing optimal anti-HIV-1 immunity has never been addressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06af7a60183355a25e4dad3dbc50661e
https://europepmc.org/articles/PMC8632342/
https://europepmc.org/articles/PMC8632342/
Autor:
Julien van Grevenynghe, Jean-Pierre Routy, Lena Cassin, Jörg H. Fritz, Hamza Loucif, Daina Avizonis, Xavier Dagenais-Lussier, David Olagnier, Cherifa Beji, Luc Choinière
Publikováno v:
Loucif, H, Dagenais-Lussier, X, Avizonis, D, Choinière, L, Beji, C, Cassin, L, Routy, J-P, Fritz, J H, Olagnier, D & van Grevenynghe, J 2022, ' Autophagy-dependent glutaminolysis drives superior IL21 production in HIV-1-specific CD4 T cells ', Autophagy, vol. 18, no. 6, pp. 1256-1273 . https://doi.org/10.1080/15548627.2021.1972403
Autophagy
Autophagy
The maintenance of a strong IL21 production in memory CD4 T cells, especially in HIV-1-specific cells, represents a major correlate of natural immune protection against the virus. However, the molecular mechanisms underlying IL21 production during HI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a234a4c67ab90f88c81f9c54aea64d0
Autor:
Hamza Loucif, Xavier Dagenais-Lussier, Roman Telittchenko, Cherifa Beji, David Olagnier, Julien van Grevenynghe
Publikováno v:
Viruses
Beji, C, Loucif, H, Telittchenko, R, Olagnier, D, Dagenais-Lussier, X & van Grevenynghe, J 2020, ' Cannabinoid-Induced Immunomodulation during Viral Infections : A Focus on Mitochondria ', Viruses, vol. 12, no. 8, 875 . https://doi.org/10.3390/v12080875
Viruses, Vol 12, Iss 875, p 875 (2020)
Beji, C, Loucif, H, Telittchenko, R, Olagnier, D, Dagenais-Lussier, X & van Grevenynghe, J 2020, ' Cannabinoid-Induced Immunomodulation during Viral Infections : A Focus on Mitochondria ', Viruses, vol. 12, no. 8, 875 . https://doi.org/10.3390/v12080875
Viruses, Vol 12, Iss 875, p 875 (2020)
This review examines the impact of cannabinoids on viral infections, as well as its effects on the mitochondria of the nervous and immune system. The paper conveys information about the beneficial and negative impacts of cannabinoids on viral infecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7f437f962ea89390b64da45f54108d
https://pubmed.ncbi.nlm.nih.gov/32796517
https://pubmed.ncbi.nlm.nih.gov/32796517
Autor:
Jean-Pierre Routy, Xavier Dagenais-Lussier, Roman Telittchenko, Julien van Grevenynghe, Cherifa Beji, Hamza Loucif
Publikováno v:
Cytokinegrowth factor reviews. 55
The notion of immuno-metabolism refers to the crosstalk between key metabolic pathways and the development/maintenance of protective immunity in the context of physiological processes and anti-microbial defenses. Enthusiasm for immuno-metabolism in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a735c51981b41bd635d1552dd3ac9f8b
https://pubmed.ncbi.nlm.nih.gov/32151523
https://pubmed.ncbi.nlm.nih.gov/32151523
Autor:
Simona Stäger, Julien van Grevenynghe, Armstrong Murira, Xavier Dagenais-Lussier, Steven Gouard, Cécile Tremblay, Hamza Loucif
Publikováno v:
Cytokine and Growth Factor Reviews
Cytokine and Growth Factor Reviews, Elsevier, 2018, 40, pp.90-98. ⟨10.1016/j.cytogfr.2018.03.010⟩
Cytokine and Growth Factor Reviews, Elsevier, 2018, 40, pp.90-98. ⟨10.1016/j.cytogfr.2018.03.010⟩
International audience; Antiretroviral therapy (ART) has dramatically reduced HIV-1-associated morbidity and mortality, and has transformed HIV-1 infection into a manageable chronic condition by suppressing viral replication. However, despite recent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ad476991c36d33ac13c9f108ef5c2a
https://doi.org/10.1016/j.cytogfr.2018.03.010
https://doi.org/10.1016/j.cytogfr.2018.03.010