Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Xavier Coumoul"'
Publikováno v:
FEBS Open Bio, Vol 14, Iss 9, Pp 1397-1419 (2024)
Although the concept of endocrine disruptors first appeared almost 30 years ago, the relatively recent involvement of these substances in the etiology of metabolic pathologies (obesity, diabetes, hepatic steatosis, etc.) has given rise to the concept
Externí odkaz:
https://doaj.org/article/719608f26618488288b226f9675190ee
Autor:
Thomas Jaylet, Thibaut Coustillet, Nicola M. Smith, Barbara Viviani, Birgitte Lindeman, Lucia Vergauwen, Oddvar Myhre, Nurettin Yarar, Johanna M. Gostner, Pablo Monfort-Lanzas, Florence Jornod, Henrik Holbech, Xavier Coumoul, Dimosthenis A. Sarigiannis, Philipp Antczak, Anna Bal-Price, Ellen Fritsche, Eliska Kuchovska, Antonios K. Stratidakis, Robert Barouki, Min Ji Kim, Olivier Taboureau, Marcin W. Wojewodzic, Dries Knapen, Karine Audouze
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
Introduction: The Adverse Outcome Pathway (AOP) concept facilitates rapid hazard assessment for human health risks. AOPs are constantly evolving, their number is growing, and they are referenced in the AOP-Wiki database, which is supported by the OEC
Externí odkaz:
https://doaj.org/article/79c175e3c33b416192eff9788af98751
Autor:
Laury Sellem, Bernard Srour, Guillaume Javaux, Eloi Chazelas, Benoit Chassaing, Emilie Viennois, Charlotte Debras, Nathalie Druesne-Pecollo, Younes Esseddik, Fabien Szabo de Edelenyi, Nathalie Arnault, Cédric Agaësse, Alexandre De Sa, Rebecca Lutchia, Inge Huybrechts, Augustin Scalbert, Fabrice Pierre, Xavier Coumoul, Chantal Julia, Emmanuelle Kesse-Guyot, Benjamin Allès, Pilar Galan, Serge Hercberg, Mélanie Deschasaux-Tanguy, Mathilde Touvier
Publikováno v:
PLoS Medicine, Vol 21, Iss 2, p e1004338 (2024)
BackgroundEmulsifiers are widely used food additives in industrially processed foods to improve texture and enhance shelf-life. Experimental research suggests deleterious effects of emulsifiers on the intestinal microbiota and the metabolome, leading
Externí odkaz:
https://doaj.org/article/ddf3dd229f454f1f8ffa6ec24af3aeb0
Autor:
Carolina Duarte Hospital, Arnaud Tête, Kloé Debizet, Jules Imler, Céline Tomkiewicz-Raulet, Etienne B. Blanc, Robert Barouki, Xavier Coumoul, Sylvie Bortoli
Publikováno v:
Environment International, Vol 180, Iss , Pp 108219- (2023)
Succinate dehydrogenase inhibitors (SDHi) are fungicides used to control the proliferation of pathogenic fungi in crops. Their mode of action is based on blocking the activity of succinate dehydrogenase (SDH), a universal enzyme expressed by all spec
Externí odkaz:
https://doaj.org/article/b1abd25c45944828ace5a5182fbb0bda
Autor:
Haidar Djemai, Rami Hammad, Ibrahim M. Dabayebeh, Saleh Hammad, Abdellah Merzouk, Xavier Coumoul, Philippe Noirez
Publikováno v:
Archives of Public Health, Vol 80, Iss 1, Pp 1-5 (2022)
Highlights • Physical inactivity during COVID-19 lockdowns may damage health. • Risk of contamination by aerosols is higher during high-intensity urban outdoor exercise. • Angiotensin converting enzyme 2 (ACE2) could play key role in SARS-CoV-2
Externí odkaz:
https://doaj.org/article/e6dbf8c9836a43d79accd5950fec09e5
Autor:
Marc Audebert, Ann-Sophie Assmann, Amaya Azqueta, Pavel Babica, Emilio Benfenati, Sylvie Bortoli, Peter Bouwman, Albert Braeuning, Tanja Burgdorf, Xavier Coumoul, Kloé Debizet, Maria Dusinska, Norman Ertych, Jörg Fahrer, Verena Fetz, Ludovic Le Hégarat, Adela López de Cerain, Harm J. Heusinkveld, Kevin Hogeveen, Miriam N. Jacobs, Mirjam Luijten, Giuseppa Raitano, Cynthia Recoules, Elise Rundén-Pran, Mariam Saleh, Iva Sovadinová, Martina Stampar, Lea Thibol, Céline Tomkiewicz, Ariane Vettorazzi, Bob Van de Water, Naouale El Yamani, Bojana Zegura, Michael Oelgeschläger
Publikováno v:
Frontiers in Toxicology, Vol 5 (2023)
Carcinogenic chemicals, or their metabolites, can be classified as genotoxic or non-genotoxic carcinogens (NGTxCs). Genotoxic compounds induce DNA damage, which can be detected by an established in vitro and in vivo battery of genotoxicity assays. Fo
Externí odkaz:
https://doaj.org/article/bb67b7cd857c45a58747146a121d489d
Autor:
Louise Benoit, Meriem Koual, Céline Tomkiewicz, Anne-Sophie Bats, Jean-Philippe Antignac, Xavier Coumoul, Robert Barouki, German Cano-Sancho
Publikováno v:
Environment International, Vol 170, Iss , Pp 107615- (2022)
Introduction: Breast cancer (BC) is frequent with a poor prognosis in case of metastasis. The role of the environment has been poorly evaluated in its progression. We searched to assess whether a mixture of pollutants could be responsible of BC aggre
Externí odkaz:
https://doaj.org/article/3f6ff450000745cf8a1265b059c1566d
Autor:
Eloi Chazelas, Nathalie Druesne-Pecollo, Younes Esseddik, Fabien Szabo de Edelenyi, Cédric Agaesse, Alexandre De Sa, Rebecca Lutchia, Pauline Rebouillat, Bernard Srour, Charlotte Debras, Gaëlle Wendeu-Foyet, Inge Huybrechts, Fabrice Pierre, Xavier Coumoul, Chantal Julia, Emmanuelle Kesse-Guyot, Benjamin Allès, Pilar Galan, Serge Hercberg, Mélanie Deschasaux-Tanguy, Mathilde Touvier
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-21 (2021)
Abstract Food additives (e.g. artificial sweeteners, emulsifiers, dyes, etc.) are ingested by billions of individuals daily. Some concerning results, mainly derived from animal and/or cell-based experimental studies, have recently emerged suggesting
Externí odkaz:
https://doaj.org/article/37e61ff3f21e4345a36e9091a4057aa4
Autor:
Louise Benoit, Florence Jornod, Elias Zgheib, Celine Tomkiewicz, Meriem Koual, Thibaut Coustillet, Robert Barouki, Karine Audouze, Mathieu Vinken, Xavier Coumoul
Publikováno v:
Environment International, Vol 165, Iss , Pp 107323- (2022)
Adverse outcome pathways (AOPs) are formalized and structured linear concepts that connect one molecular initiating event (MIE) to an adverse outcome (AO) via different key events (KE) through key event relationships (KER). They are mainly used in ec
Externí odkaz:
https://doaj.org/article/46f34640c91f421cb417dd022cb6617c
Autor:
Gaëlle Deval, Margaux Nedder, Séverine Degrelle, Jasmina Rogozarski, Marie-Léone Vignaud, Audrey Chissey, Stacy Colzin, Christelle Laguillier-Morizot, Xavier Coumoul, Sonja Boland, Thierry Fournier, Amal Zerrad-Saadi, Ioana Ferecatu
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5439 (2023)
Human placenta is a multifunctional interface between maternal and fetal blood. Studying the impact of pollutants on this organ is crucial because many xenobiotics in maternal blood can accumulate in placental cells or pass into the fetal circulation
Externí odkaz:
https://doaj.org/article/687708debeb04f1d9ca6af3d6258cbe7